A global genetic interaction network maps a wiring diagram of cellular function M Costanzo, B VanderSluis, EN Koch, A Baryshnikova, C Pons, G Tan, ... Science 353 (6306), aaf1420, 2016 | 1209 | 2016 |
Gene regulation by antisense transcription V Pelechano, LM Steinmetz Nature Reviews Genetics 14 (12), 880-893, 2013 | 716 | 2013 |
Rapid detection of COVID-19 coronavirus using a reverse transcriptional loop-mediated isothermal amplification (RT-LAMP) diagnostic platform L Yu, S Wu, X Hao, X Dong, L Mao, V Pelechano, WH Chen, X Yin Clinical chemistry 66 (7), 975-977, 2020 | 552 | 2020 |
Extensive transcriptional heterogeneity revealed by isoform profiling V Pelechano, W Wei, LM Steinmetz Nature 497 (7447), 127-131, 2013 | 465 | 2013 |
Polyadenylation site–induced decay of upstream transcripts enforces promoter directionality E Ntini, AI Järvelin, J Bornholdt, Y Chen, M Boyd, M Jørgensen, ... Nature structural & molecular biology 20 (8), 923-928, 2013 | 301 | 2013 |
Widespread co-translational RNA decay reveals ribosome dynamics V Pelechano, W Wei, LM Steinmetz Cell 161 (6), 1400-1412, 2015 | 300 | 2015 |
Functional consequences of bidirectional promoters W Wei, V Pelechano, AI Järvelin, LM Steinmetz Trends in Genetics 27 (7), 267-276, 2011 | 248 | 2011 |
A complete set of nascent transcription rates for yeast genes V Pelechano, S Chávez, JE Pérez-Ortín PLoS One 5 (11), e15442, 2010 | 193 | 2010 |
eIF5A facilitates translation termination globally and promotes the elongation of many non polyproline-specific tripeptide sequences V Pelechano, P Alepuz Nucleic acids research 45 (12), 7326-7338, 2017 | 173 | 2017 |
System-wide profiling of RNA-binding proteins uncovers key regulators of virus infection M Garcia-Moreno, M Noerenberg, S Ni, AI Järvelin, E González-Almela, ... Molecular cell 74 (1), 196-211. e11, 2019 | 160 | 2019 |
Alternative polyadenylation diversifies post‐transcriptional regulation by selective RNA–protein interactions I Gupta, S Clauder‐Münster, B Klaus, AI Järvelin, RS Aiyar, V Benes, ... Molecular systems biology 10 (2), 719, 2014 | 125 | 2014 |
Association of condensin with chromosomes depends on DNA binding by its HEAT-repeat subunits I Piazza, A Rutkowska, A Ori, M Walczak, J Metz, V Pelechano, M Beck, ... Nature structural & molecular biology 21 (6), 560-568, 2014 | 124 | 2014 |
An efficient method for genome-wide polyadenylation site mapping and RNA quantification S Wilkening, V Pelechano, AI Järvelin, MM Tekkedil, S Anders, V Benes, ... Nucleic acids research 41 (5), e65-e65, 2013 | 122 | 2013 |
Rrp6p controls mRNA poly (A) tail length and its decoration with poly (A) binding proteins M Schmid, MB Poulsen, P Olszewski, V Pelechano, C Saguez, I Gupta, ... Molecular cell 47 (2), 267-280, 2012 | 95 | 2012 |
A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage MJGW Ladds, IMM Van Leeuwen, CJ Drummond, S Chu, AR Healy, ... Nature communications 9 (1), 1107, 2018 | 89 | 2018 |
Principles for RNA metabolism and alternative transcription initiation within closely spaced promoters Y Chen, AA Pai, J Herudek, M Lubas, N Meola, AI Järvelin, R Andersson, ... Nature genetics 48 (9), 984-994, 2016 | 80 | 2016 |
The transcriptional inhibitor thiolutin blocks mRNA degradation in yeast V Pelechano, JE Pérez‐Ortín Yeast 25 (2), 85-92, 2008 | 80 | 2008 |
Regulon-specific control of transcription elongation across the yeast genome V Pelechano, S Jimeno-González, A Rodríguez-Gil, J García-Martínez, ... PLoS genetics 5 (8), e1000614, 2009 | 79 | 2009 |
Transcription-driven chromatin repression of Intragenic transcription start sites M Nielsen, R Ard, X Leng, M Ivanov, P Kindgren, V Pelechano, ... PLoS genetics 15 (2), e1007969, 2019 | 74 | 2019 |
Landscape and dynamics of transcription initiation in the malaria parasite Plasmodium falciparum SH Adjalley, CD Chabbert, B Klaus, V Pelechano, LM Steinmetz Cell reports 14 (10), 2463-2475, 2016 | 70 | 2016 |