Piperine as an inhibitor of Rv1258c, a putative multidrug efflux pump of Mycobacterium tuberculosis S Sharma, M Kumar, S Sharma, A Nargotra, S Koul, IA Khan Journal of Antimicrobial Chemotherapy 65 (8), 1694-1701, 2010 | 221 | 2010 |
Capsaicin, a novel inhibitor of the NorA efflux pump, reduces the intracellular invasion of Staphylococcus aureus NP Kalia, P Mahajan, R Mehra, A Nargotra, JP Sharma, S Koul, IA Khan Journal of antimicrobial chemotherapy 67 (10), 2401-2408, 2012 | 215 | 2012 |
Synthesis of novel 1, 2, 3-triazole based benzoxazolinones: their TNF-α based molecular docking with in-vivo anti-inflammatory, antinociceptive activities and ulcerogenic risk … S Haider, MS Alam, H Hamid, S Shafi, A Nargotra, P Mahajan, S Nazreen, ... European journal of medicinal chemistry 70, 579-588, 2013 | 75 | 2013 |
Design of novel 3-pyrimidinylazaindole CDK2/9 inhibitors with potent in vitro and in vivo antitumor efficacy in a triple-negative breast cancer model U Singh, G Chashoo, SU Khan, P Mahajan, A Nargotra, G Mahajan, ... Journal of Medicinal Chemistry 60 (23), 9470-9489, 2017 | 59 | 2017 |
Quantitative structure activity relationship (QSAR) of piperine analogsfor bacterial NorA efflux pump inhibitors A Nargotra, S Sharma, JL Koul, PL Sangwan, IA Khan, A Kumar, ... European journal of medicinal chemistry 44 (10), 4128-4135, 2009 | 48 | 2009 |
Molecular characterization of UGT94F2 and UGT86C4, two glycosyltransferases from Picrorhiza kurrooa: comparative structural insight and evaluation of substrate recognition WW Bhat, N Dhar, S Razdan, S Rana, R Mehra, A Nargotra, RS Dhar, ... PloS one 8 (9), e73804, 2013 | 46 | 2013 |
Saponins as novel TNF-α inhibitors: isolation of saponins and a nor-pseudoguaianolide from Parthenium hysterophorus BA Shah, R Chib, P Gupta, VK Sethi, S Koul, SS Andotra, A Nargotra, ... Organic & Biomolecular Chemistry 7 (16), 3230-3235, 2009 | 42 | 2009 |
Synthesis of 5-substituted-1H-pyrazolo [4, 3-d] pyrimidin-7 (6H)-one analogs and their biological evaluation as anticancer agents: mTOR inhibitors GL Reddy, SK Guru, M Srinivas, AS Pathania, P Mahajan, A Nargotra, ... European Journal of Medicinal Chemistry 80, 201-208, 2014 | 41 | 2014 |
Screening of antitubercular compound library identifies novel ATP synthase inhibitors of Mycobacterium tuberculosis S Kumar, R Mehra, S Sharma, NP Bokolia, D Raina, A Nargotra, PP Singh, ... Tuberculosis 108, 56-63, 2018 | 40 | 2018 |
Quantitative structure–activity relationship (QSAR) of aryl alkenyl amides/imines for bacterial efflux pump inhibitors A Nargotra, S Koul, S Sharma, IA Khan, A Kumar, N Thota, JL Koul, ... European journal of medicinal chemistry 44 (1), 229-238, 2009 | 39 | 2009 |
Design and synthesis of novel N, N′-glycoside derivatives of 3, 3′-diindolylmethanes as potential antiproliferative agents DK Sharma, B Rah, MR Lambu, A Hussain, SK Yousuf, AK Tripathi, ... MedChemComm 3 (9), 1082-1091, 2012 | 37 | 2012 |
High-throughput screen identifies small molecule inhibitors targeting acetyltransferase activity of Mycobacterium tuberculosis GlmU C Rani, R Mehra, R Sharma, R Chib, P Wazir, A Nargotra, IA Khan Tuberculosis 95 (6), 664-677, 2015 | 35 | 2015 |
Molecular modeling and snake venom phospholipase A2 inhibition by phenolic compounds: Structure–activity relationship MI Alam, MA Alam, O Alam, A Nargotra, SC Taneja, S Koul European journal of medicinal chemistry 114, 209-219, 2016 | 34 | 2016 |
Computationally Guided Identification of Novel Mycobacterium tuberculosis GlmU Inhibitory Leads, Their Optimization, and in Vitro Validation R Mehra, C Rani, P Mahajan, RA Vishwakarma, IA Khan, A Nargotra ACS combinatorial science 18 (2), 100-116, 2016 | 34 | 2016 |
Benzothiazole Derivative as a Novel Mycobacterium tuberculosis Shikimate Kinase Inhibitor: Identification and Elucidation of Its Allosteric Mode of Inhibition R Mehra, VS Rajput, M Gupta, R Chib, A Kumar, P Wazir, IA Khan, ... Journal of Chemical Information and Modeling 56 (5), 930-940, 2016 | 33 | 2016 |
Screening of antitubercular compound library identifies novel shikimate kinase inhibitors of Mycobacterium tuberculosis VS Rajput, R Mehra, S Kumar, A Nargotra, PP Singh, IA Khan Applied microbiology and biotechnology 100, 5415-5426, 2016 | 32 | 2016 |
In silico identification of viper phospholipaseA2 inhibitors: validation by in vitro, in vivo studies A Nargotra, S Sharma, MI Alam, Z Ahmed, A Bhagat, SC Taneja, GN Qazi, ... Journal of molecular modeling 17, 3063-3073, 2011 | 32 | 2011 |
Discovery of a new donepezil-like acetylcholinesterase inhibitor for targeting Alzheimer’s disease: computational studies with biological validation BA Akhoon, S Choudhary, H Tiwari, A Kumar, MR Barik, L Rathor, ... Journal of Chemical Information and Modeling 60 (10), 4717-4729, 2020 | 29 | 2020 |
Discovery of novel pyrazolopyrimidinone analogs as potent inhibitors of phosphodiesterase type-5 SD Sawant, GL Reddy, MI Dar, M Srinivas, G Gupta, PK Sahu, P Mahajan, ... Bioorganic & Medicinal Chemistry 23 (9), 2121-2128, 2015 | 29 | 2015 |
Anti-asthmatic activity of azepino [2, 1-b] quinazolones, synthetic analogues of vasicine, an alkaloid from Adhatoda vasica S Rayees, NK Satti, R Mehra, A Nargotra, S Rasool, A Sharma, PK Sahu, ... Medicinal Chemistry Research 23, 4269-4279, 2014 | 29 | 2014 |