Christopher S. Chen, M.D., Ph.D.
Christopher S. Chen, M.D., Ph.D.
Biomedical Engineering, Boston University; The Wyss Institute for Biologically Inspired Engineering
Verificeret mail på bu.edu - Startside
Citeret af
Citeret af
Geometric control of cell life and death
CS Chen, M Mrksich, S Huang, GM Whitesides, DE Ingber
Science 276 (5317), 1425-1428, 1997
Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment
R McBeath, DM Pirone, CM Nelson, K Bhadriraju, CS Chen
Developmental cell 6 (4), 483-495, 2004
Cells lying on a bed of microneedles: an approach to isolate mechanical force
JL Tan, J Tien, DM Pirone, DS Gray, K Bhadriraju, CS Chen
Proceedings of the National Academy of Sciences 100 (4), 1484-1489, 2003
Control of stem cell fate by physical interactions with the extracellular matrix
F Guilak, DM Cohen, BT Estes, JM Gimble, W Liedtke, CS Chen
Cell stem cell 5 (1), 17-26, 2009
Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues
JS Miller, KR Stevens, MT Yang, BM Baker, DHT Nguyen, DM Cohen, ...
Nature materials 11 (9), 768-774, 2012
Deconstructing the third dimension–how 3D culture microenvironments alter cellular cues
BM Baker, CS Chen
Journal of cell science 125 (13), 3015-3024, 2012
Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure
AJ Maniotis, CS Chen, DE Ingber
Proceedings of the National Academy of Sciences 94 (3), 849-854, 1997
Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics
C Grashoff, BD Hoffman, MD Brenner, R Zhou, M Parsons, MT Yang, ...
Nature 466 (7303), 263-266, 2010
Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels
S Khetan, M Guvendiren, WR Legant, DM Cohen, CS Chen, JA Burdick
Nature materials 12 (5), 458-465, 2013
Mechanical regulation of cell function with geometrically modulated elastomeric substrates
J Fu, YK Wang, MT Yang, RA Desai, X Yu, Z Liu, CS Chen
Nature methods 7 (9), 733-736, 2010
Emergent patterns of growth controlled by multicellular form and mechanics
CM Nelson, RP Jean, JL Tan, WF Liu, NJ Sniadecki, AA Spector, ...
Proceedings of the National Academy of Sciences 102 (33), 11594-11599, 2005
Micropatterned surfaces for control of cell shape, position, and function
CS Chen, M Mrksich, S Huang, GM Whitesides, DE Ingber
Biotechnology Progress 14 (3), 356-363, 1998
Mechanotransduction in development: a growing role for contractility
MA Wozniak, CS Chen
Nature reviews Molecular cell biology 10 (1), 34-43, 2009
Mechanical tugging force regulates the size of cell–cell junctions
Z Liu, JL Tan, DM Cohen, MT Yang, NJ Sniadecki, SA Ruiz, CM Nelson, ...
Proceedings of the National Academy of Sciences 107 (22), 9944-9949, 2010
Versatile, fully automated, microfluidic cell culture system
R Gómez-Sjöberg, AA Leyrat, DM Pirone, CS Chen, SR Quake
Analytical chemistry 79 (22), 8557-8563, 2007
Nanopattern-induced changes in morphology and motility of smooth muscle cells
EKF Yim, RM Reano, SW Pang, AF Yee, CS Chen, KW Leong
Biomaterials 26 (26), 5405-5413, 2005
Cell shape provides global control of focal adhesion assembly
CS Chen, JL Alonso, E Ostuni, GM Whitesides, DE Ingber
Biochemical and biophysical research communications 307 (2), 355-361, 2003
Measurement of mechanical tractions exerted by cells in three-dimensional matrices
WR Legant, JS Miller, BL Blakely, DM Cohen, GM Genin, CS Chen
Nature methods 7 (12), 969-971, 2010
Mechanotransduction at cell-matrix and cell-cell contacts
CS Chen, J Tan, J Tien
Annu. Rev. Biomed. Eng. 6, 275-302, 2004
Microcontact printing: A tool to pattern
SA Ruiz, CS Chen
Soft Matter 3 (2), 168-177, 2007
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