Peter Vangheluwe
Peter Vangheluwe
Laboratory of Cellular Transport Systems KU Leuven
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Modulating sarco (endo) plasmic reticulum Ca2+ ATPase 2 (SERCA2) activity: cell biological implications
P Vangheluwe, L Raeymaekers, L Dode, F Wuytack
Cell calcium 38 (3-4), 291-302, 2005
The Ca2+ pumps of the endoplasmic reticulum and Golgi apparatus
I Vandecaetsbeek, P Vangheluwe, L Raeymaekers, F Wuytack, ...
Cold Spring Harbor perspectives in biology 3 (5), a004184, 2011
Sarcolipin and phospholamban mRNA and protein expression in cardiac and skeletal muscle of different species
P Vangheluwe, M Schuermans, E Zádor, E Waelkens, L Raeymaekers, ...
Biochemical Journal 389 (1), 151-159, 2005
Replacement of the Muscle-Specific Sarcoplasmic Reticulum Ca2+-ATPase Isoform SERCA2a by the Nonmuscle SERCA2b Homologue Causes Mild Concentric …
M Ver Heyen, S Heymans, G Antoons, T Reed, M Periasamy, B Awede, ...
Circulation research 89 (9), 838-846, 2001
Loss-of-function mutations in the ATP13A2/PARK9 gene cause complicated hereditary spastic paraplegia (SPG78)
A Estrada-Cuzcano, S Martin, T Chamova, M Synofzik, D Timmann, ...
Brain 140 (2), 287-305, 2017
X Loyer, AM Gómez, P Milliez, M Fernandez-Velasco, P Vangheluwe, ...
Circulation 117 (25), 3187-3198, 2008
Dyslipidaemia in type II diabetic mice does not aggravate contractile impairment but increases ventricular stiffness
A Van den Bergh, A Vanderper, P Vangheluwe, F Desjardins, ...
Cardiovascular research 77 (2), 371-379, 2008
Intracellular Ca2+- and Mn2+-Transport ATPases
P Vangheluwe, MR Sepulveda, L Missiaen, L Raeymaekers, F Wuytack, ...
Chemical reviews 109 (10), 4733-4759, 2009
Structural basis for the high Ca2+ affinity of the ubiquitous SERCA2b Ca2+ pump
I Vandecaetsbeek, M Trekels, M De Maeyer, H Ceulemans, E Lescrinier, ...
Proceedings of the National Academy of Sciences 106 (44), 18533-18538, 2009
Regulation of endoplasmic reticulum Ca2+ oscillations in mammalian eggs
T Wakai, N Zhang, P Vangheluwe, RA Fissore
Journal of cell science 126 (24), 5714-5724, 2013
New perspectives on the role of SERCA2's Ca2+ affinity in cardiac function
P Vangheluwe, KR Sipido, L Raeymaekers, F Wuytack
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1763 (11), 1216-1228, 2006
Sarcoplasmic reticulum calcium uptake and speed of relaxation are depressed in nebulin‐free skeletal muscle
CAC Ottenheijm, C Fong, P Vangheluwe, F Wuytack, GJ Babu, ...
The FASEB Journal 22 (8), 2912-2919, 2008
A novel approach to analyze lysosomal dysfunctions through subcellular proteomics and lipidomics: the case of NPC1 deficiency
AK Tharkeshwar, J Trekker, W Vermeire, J Pauwels, R Sannerud, ...
Scientific reports 7 (1), 1-20, 2017
A lipid switch unlocks Parkinson’s disease-associated ATP13A2
T Holemans, DM Sørensen, S van Veen, S Martin, D Hermans, ...
Proceedings of the National Academy of Sciences 112 (29), 9040-9045, 2015
Cellular function and pathological role of ATP13A2 and related P-type transport ATPases in Parkinson's disease and other neurological disorders
S van Veen, DM Sørensen, T Holemans, HW Holen, MG Palmgren, ...
Frontiers in molecular neuroscience 7, 48, 2014
Sarco (endo) plasmic reticulum calcium ATPase (SERCA) inhibition by sarcolipin is encoded in its luminal tail
PA Gorski, JP Glaves, P Vangheluwe, HS Young
Journal of Biological Chemistry 288 (12), 8456-8467, 2013
A SERCA2 pump with an increased Ca2+ affinity can lead to severe cardiac hypertrophy, stress intolerance and reduced life span
P Vangheluwe, M Tjwa, A Van Den Bergh, WE Louch, M Beullens, ...
Journal of molecular and cellular cardiology 41 (2), 308-317, 2006
LRRK2 mutations impair depolarization-induced mitophagy through inhibition of mitochondrial accumulation of RAB10
F Wauters, T Cornelissen, D Imberechts, S Martin, B Koentjoro, C Sue, ...
Autophagy 16 (2), 203-222, 2020
Ca2+ transport ATPase isoforms SERCA2a and SERCA2b are targeted to the same sites in the murine heart
P Vangheluwe, WE Louch, M Ver Heyen, K Sipido, L Raeymaekers, ...
Cell calcium 34 (6), 457-464, 2003
Evaluation of manganese uptake and toxicity in mouse brain during continuous MnCl2 administration using osmotic pumps
MR Sepulveda, T Dresselaers, P Vangheluwe, W Everaerts, ...
Contrast media & molecular imaging 7 (4), 426-434, 2012
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