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Simon Glerup
Simon Glerup
Verificeret mail på biokemi.au.dk
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Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling
CB Vaegter, P Jansen, AW Fjorback, S Glerup, S Skeldal, M Kjolby, ...
Nature neuroscience 14 (1), 54-61, 2011
2132011
The hypercholesterolemia-risk gene SORT1 facilitates PCSK9 secretion
C Gustafsen, M Kjolby, M Nyegaard, M Mattheisen, J Lundhede, ...
Cell metabolism 19 (2), 310-318, 2014
1892014
APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1
M Tachibana, ML Holm, CC Liu, M Shinohara, T Aikawa, H Oue, ...
The Journal of clinical investigation 129 (3), 1272-1277, 2019
1232019
Sortilin and SorLA display distinct roles in processing and trafficking of amyloid precursor protein
C Gustafsen, S Glerup, LT Pallesen, D Olsen, OM Andersen, A Nykjær, ...
Journal of Neuroscience 33 (1), 64-71, 2013
1162013
Heparan sulfate proteoglycans present PCSK9 to the LDL receptor
C Gustafsen, D Olsen, J Vilstrup, S Lund, A Reinhardt, N Wellner, ...
Nature communications 8 (1), 503, 2017
1022017
SorCS2 regulates dopaminergic wiring and is processed into an apoptotic two-chain receptor in peripheral glia
S Glerup, D Olsen, CB Vaegter, C Gustafsen, SS Sjoegaard, G Hermey, ...
Neuron 82 (5), 1074-1087, 2014
932014
Physiological and therapeutic regulation of PCSK9 activity in cardiovascular disease
S Glerup, R Schulz, U Laufs, KD Schlüter
Basic research in cardiology 112, 1-23, 2017
922017
SorLA regulates the activity of lipoprotein lipase by intracellular trafficking
SC Klinger, S Glerup, MK Raarup, MC Mari, M Nyegaard, G Koster, ...
Journal of cell science 124 (7), 1095-1105, 2011
912011
SorCS2 is required for BDNF-dependent plasticity in the hippocampus
S Glerup, U Bolcho, S Mølgaard, S Bøggild, CB Vaegter, AH Smith, ...
Molecular psychiatry 21 (12), 1740-1751, 2016
902016
Sortilin-related receptor SORCS3 is a postsynaptic modulator of synaptic depression and fear extinction
T Breiderhoff, GB Christiansen, LT Pallesen, C Vaegter, A Nykjaer, ...
PloS one 8 (9), e75006, 2013
842013
Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model
P Bøttger, S Glerup, B Gesslein, NB Illarionova, TJ Isaksen, A Heuck, ...
Scientific Reports 6 (1), 22047, 2016
802016
SorLA controls neurotrophic activity by sorting of GDNF and its receptors GFRα1 and RET
S Glerup, M Lume, D Olsen, JR Nyengaard, CB Vaegter, C Gustafsen, ...
Cell reports 3 (1), 186-199, 2013
702013
Mapping of the interaction site between sortilin and the p75 neurotrophin receptor reveals a regulatory role for the sortilin intracellular domain in p75 neurotrophin receptor …
S Skeldal, AM Sykes, S Glerup, D Matusica, N Palstra, H Autio, Z Boskovic, ...
Journal of Biological Chemistry 287 (52), 43798-43809, 2012
662012
Temporal course of pregnancy-associated plasma protein-A in angioplasty-treated ST-elevation myocardial infarction patients and potential significance of concomitant heparin …
CJ Terkelsen, C Oxvig, BL Nørgaard, S Glerup, TS Poulsen, JF Lassen, ...
The American journal of cardiology 103 (1), 29-35, 2009
602009
Proteinase inhibition by proform of eosinophil major basic protein (pro-MBP) is a multistep process of intra-and intermolecular disulfide rearrangements
S Glerup, HB Boldt, MT Overgaard, L Sottrup-Jensen, LC Giudice, ...
Journal of Biological Chemistry 280 (11), 9823-9832, 2005
522005
Increased serum levels of sortilin are associated with depression and correlated with BDNF and VEGF
HN Buttenschøn, D Demontis, M Kaas, B Elfving, S Mølgaard, ...
Translational psychiatry 5 (11), e677-e677, 2015
472015
Sortilins in neurotrophic factor signaling
S Glerup, A Nykjaer, CB Vægter
Neurotrophic factors, 165-189, 2014
472014
Inhibition of proteolysis by the proform of eosinophil major basic protein (proMBP) requires covalent binding to its target proteinase
MT Overgaard, S Glerup, HB Boldt, V Rodacker, IM Olsen, M Christiansen, ...
FEBS letters 560 (1-3), 147-152, 2004
382004
Cognitive deficits caused by a disease-mutation in the α3 Na+/K+-ATPase isoform
TH Holm, TJ Isaksen, S Glerup, A Heuck, P Bøttger, EM Füchtbauer, ...
Scientific reports 6 (1), 31972, 2016
322016
Whole-exome sequencing reveals increased burden of rare functional and disruptive variants in candidate risk genes in individuals with persistent attention-deficit …
D Demontis, F Lescai, A Børglum, S Glerup, SD Østergaard, O Mors, Q Li, ...
Journal of the American Academy of Child and Adolescent Psychiatry 55 (6 …, 2016
322016
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