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Brent Martin
Brent Martin
Chemical Biology, Scorpion Therapeutics
Verified email at scorpiontx.com
Title
Cited by
Cited by
Year
New biarsenical ligands and tetracysteine motifs for protein labeling in vitro and in vivo: synthesis and biological applications
SR Adams, RE Campbell, LA Gross, BR Martin, GK Walkup, Y Yao, ...
Journal of the American Chemical Society 124 (21), 6063-6076, 2002
11822002
Large-scale profiling of protein palmitoylation in mammalian cells
BR Martin, BF Cravatt
Nature methods 6 (2), 135-138, 2009
5162009
Mammalian cell–based optimization of the biarsenical-binding tetracysteine motif for improved fluorescence and affinity
BR Martin, BNG Giepmans, SR Adams, RY Tsien
Nature biotechnology 23 (10), 1308-1314, 2005
5112005
Global profiling of dynamic protein palmitoylation
BR Martin, C Wang, A Adibekian, SE Tully, BF Cravatt
Nature methods 9 (1), 84-89, 2012
3602012
Click-generated triazole ureas as ultrapotent in vivo–active serine hydrolase inhibitors
A Adibekian, BR Martin, C Wang, KL Hsu, DA Bachovchin, S Niessen, ...
Nature chemical biology 7 (7), 469-478, 2011
2682011
Profiling targets of the irreversible palmitoylation inhibitor 2-bromopalmitate
D Davda, MA El Azzouny, CTMB Tom, JL Hernandez, JD Majmudar, ...
ACS chemical biology 8 (9), 1912-1917, 2013
1822013
DHHC5 protein palmitoylates flotillin-2 and is rapidly degraded on induction of neuronal differentiation in cultured cells
Y Li, BR Martin, BF Cravatt, SL Hofmann
Journal of Biological Chemistry 287 (1), 523-530, 2012
1432012
Confirming target engagement for reversible inhibitors in vivo by kinetically tuned activity-based probes
A Adibekian, BR Martin, JW Chang, KL Hsu, K Tsuboi, DA Bachovchin, ...
Journal of the American Chemical Society 134 (25), 10345-10348, 2012
1332012
Protein depalmitoylases
SJ Won, M Cheung See Kit, BR Martin
Critical reviews in biochemistry and molecular biology 53 (1), 83-98, 2018
1092018
Dimethyl itaconate is not metabolized into itaconate intracellularly
M ElAzzouny, CTMB Tom, CR Evans, LL Olson, MJ Tanga, KA Gallagher, ...
Journal of Biological Chemistry 292 (12), 4766-4769, 2017
862017
Global analysis of palmitoylated proteins in Toxoplasma gondii
IT Foe, MA Child, JD Majmudar, S Krishnamurthy, WA van der Linden, ...
Cell host & microbe 18 (4), 501-511, 2015
832015
Variable-velocity traveling-wave ion mobility separation enhancing peak capacity for data-independent acquisition proteomics
SE Haynes, DA Polasky, SM Dixit, JD Majmudar, K Neeson, BT Ruotolo, ...
Analytical chemistry 89 (11), 5669-5672, 2017
782017
Tunable heteroaromatic sulfones enhance in-cell cysteine profiling
HF Motiwala, YH Kuo, BL Stinger, BA Palfey, BR Martin
Journal of the American Chemical Society 142 (4), 1801-1810, 2019
692019
APT2 inhibition restores scribble localization and S-palmitoylation in snail-transformed cells
JL Hernandez, D Davda, MCS Kit, JD Majmudar, SJ Won, M Gang, ...
Cell chemical biology 24 (1), 87-97, 2017
692017
Isoform-specific PKA dynamics revealed by dye-triggered aggregation and DAKAP1α-mediated localization in living cells
BR Martin, TJ Deerinck, MH Ellisman, SS Taylor, RY Tsien
Chemistry & biology 14 (9), 1031-1042, 2007
652007
Molecular mechanism for isoform-selective inhibition of acyl protein thioesterases 1 and 2 (APT1 and APT2)
SJ Won, D Davda, KJ Labby, SY Hwang, R Pricer, JD Majmudar, ...
ACS chemical biology 11 (12), 3374-3382, 2016
622016
Proteomic analysis of S-acylated proteins in human B cells reveals palmitoylation of the immune regulators CD20 and CD23
C Ivaldi, BR Martin, S Kieffer-Jaquinod, A Chapel, T Levade, J Garin, ...
PloS one 7 (5), e37187, 2012
582012
A Mechanism Regulating G Protein-coupled Receptor Signaling That Requires Cycles of Protein Palmitoylation and Depalmitoylation*♦
L Jia, M Chisari, MH Maktabi, C Sobieski, H Zhou, AM Konopko, ...
Journal of Biological Chemistry 289 (9), 6249-6257, 2014
532014
Fat chance! Getting a grip on a slippery modification
CTMB Tom, BR Martin
ACS chemical biology 8 (1), 46-57, 2013
532013
Harnessing redox cross-reactivity to profile distinct cysteine modifications
JD Majmudar, AM Konopko, KJ Labby, CTMB Tom, JE Crellin, A Prakash, ...
Journal of the American Chemical Society 138 (6), 1852-1859, 2016
522016
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