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Graham Robert Bignell
Graham Robert Bignell
Senior Staff Scientist, Wellcome Trust Sanger Institute
Verified email at sanger.ac.uk
Title
Cited by
Cited by
Year
Mutations of the BRAF gene in human cancer
H Davies, GR Bignell, C Cox, P Stephens, S Edkins, S Clegg, J Teague, ...
Nature 417 (6892), 949-954, 2002
125542002
Signatures of mutational processes in human cancer
LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ...
Nature 500 (7463), 415-421, 2013
96522013
Identification of the breast cancer susceptibility gene BRCA2
R Wooster, G Bignell, J Lancaster, S Swift, S Seal, J Mangion, N Collins, ...
Nature 378 (6559), 789-792, 1995
48851995
Patterns of somatic mutation in human cancer genomes
C Greenman, P Stephens, R Smith, GL Dalgliesh, C Hunter, G Bignell, ...
Nature 446 (7132), 153-158, 2007
36962007
Massive genomic rearrangement acquired in a single catastrophic event during cancer development
PJ Stephens, CD Greenman, B Fu, F Yang, GR Bignell, LJ Mudie, ...
cell 144 (1), 27-40, 2011
25282011
Systematic identification of genomic markers of drug sensitivity in cancer cells
MJ Garnett, EJ Edelman, SJ Heidorn, CD Greenman, A Dastur, KW Lau, ...
Nature 483 (7391), 570-575, 2012
25252012
A serine/threonine kinase gene defective in Peutz–Jeghers syndrome
A Hemminki, D Markie, I Tomlinson, E Avizienyte, S Roth, A Loukola, ...
Nature 391 (6663), 184-187, 1998
20701998
Mutational processes molding the genomes of 21 breast cancers
S Nik-Zainal, LB Alexandrov, DC Wedge, P Van Loo, CD Greenman, ...
Cell 149 (5), 979-993, 2012
20362012
A comprehensive catalogue of somatic mutations from a human cancer genome
ED Pleasance, RK Cheetham, PJ Stephens, DJ McBride, SJ Humphray, ...
Nature 463 (7278), 191-196, 2010
20092010
The landscape of cancer genes and mutational processes in breast cancer
PJ Stephens, PS Tarpey, H Davies, P Van Loo, C Greenman, DC Wedge, ...
Nature 486 (7403), 400-404, 2012
18852012
A landscape of pharmacogenomic interactions in cancer
F Iorio, TA Knijnenburg, DJ Vis, GR Bignell, MP Menden, M Schubert, ...
Cell 166 (3), 740-754, 2016
16452016
The life history of 21 breast cancers
S Nik-Zainal, P Van Loo, DC Wedge, LB Alexandrov, CD Greenman, ...
Cell 149 (5), 994-1007, 2012
15292012
BRAF and RAS mutations in human lung cancer and melanoma
MS Brose, P Volpe, M Feldman, M Kumar, I Rishi, R Gerrero, E Einhorn, ...
Cancer research 62 (23), 6997, 2002
14712002
Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma
I Varela, P Tarpey, K Raine, D Huang, CK Ong, P Stephens, H Davies, ...
Nature 469 (7331), 539-542, 2011
13782011
Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes
GL Dalgliesh, K Furge, C Greenman, L Chen, G Bignell, A Butler, ...
Nature 463 (7279), 360-363, 2010
13372010
Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing
PJ Campbell, PJ Stephens, ED Pleasance, S O'Meara, H Li, T Santarius, ...
Nature genetics 40 (6), 722-729, 2008
9732008
Heterogeneity of genomic evolution and mutational profiles in multiple myeloma
N Bolli, H Avet-Loiseau, DC Wedge, P Van Loo, LB Alexandrov, ...
Nature communications 5 (1), 2997, 2014
9382014
Intragenic ERBB2 kinase mutations in tumours
P Stephens, C Hunter, G Bignell, S Edkins, H Davies, J Teague, ...
Nature 431 (7008), 525-526, 2004
9372004
Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer
G Van Haaften, GL Dalgliesh, H Davies, L Chen, G Bignell, C Greenman, ...
Nature genetics 41 (5), 521-523, 2009
9172009
Identification of the familial cylindromatosis tumour-suppressor gene
GR Bignell, W Warren, S Seal, M Takahashi, E Rapley, R Barfoot, ...
Nature genetics 25 (2), 160-165, 2000
8302000
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