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Chronic myeloid leukemia stem cells possess multiple unique features of resistance to BCR-ABL targeted therapies X Jiang, Y Zhao, C Smith, M Gasparetto, A Turhan, A Eaves, C Eaves Leukemia 21 (5), 926-935, 2007 | 455 | 2007 |
Autocrine production and action of IL-3 and granulocyte colony-stimulating factor in chronic myeloid leukemia X Jiang, A Lopez, T Holyoake, A Eaves, C Eaves Proceedings of the National Academy of Sciences 96 (22), 12804-12809, 1999 | 314 | 1999 |
Primitive quiescent leukemic cells from patients with chronic myeloid leukemia spontaneously initiate factor-independent growth in vitro in association with up-regulation of … TL Holyoake, X Jiang, HG Jorgensen, S Graham, MJ Alcorn, C Laird, ... Blood, The Journal of the American Society of Hematology 97 (3), 720-728, 2001 | 219 | 2001 |
The core autophagy protein ATG4B is a potential biomarker and therapeutic target in CML stem/progenitor cells K Rothe, H Lin, KBL Lin, A Leung, HM Wang, M Malekesmaeili, ... Blood, The Journal of the American Society of Hematology 123 (23), 3622-3634, 2014 | 207 | 2014 |
Elucidating critical mechanisms of deregulated stem cell turnover in the chronic phase of chronic myeloid leukemia TL Holyoake, X Jiang, MW Drummond, AC Eaves, CJ Eaves Leukemia 16 (4), 549-558, 2002 | 173 | 2002 |
Instability of BCR–ABL gene in primary and cultured chronic myeloid leukemia stem cells X Jiang, KM Saw, A Eaves, C Eaves Journal of the National Cancer Institute 99 (9), 680-693, 2007 | 171 | 2007 |
Different subsets of primary chronic myeloid leukemia stem cells engraft immunodeficient mice and produce a model of the human disease W Eisterer, X Jiang, O Christ, H Glimm, KH Lee, E Pang, K Lambie, ... Leukemia 19 (3), 435-441, 2005 | 166 | 2005 |
Insights into the stem cells of chronic myeloid leukemia I Sloma, X Jiang, AC Eaves, CJ Eaves Leukemia 24 (11), 1823-1833, 2010 | 144 | 2010 |
Intermittent exposure of primitive quiescent chronic myeloid leukemia cells to granulocyte-colony stimulating factor in vitro promotes their elimination by imatinib mesylate HG Jørgensen, M Copland, EK Allan, X Jiang, A Eaves, C Eaves, ... Clinical cancer research 12 (2), 626-633, 2006 | 122 | 2006 |
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B-cell-specific diversion of glucose carbon utilization reveals a unique vulnerability in B cell malignancies G Xiao, LN Chan, L Klemm, D Braas, Z Chen, H Geng, QC Zhang, ... Cell 173 (2), 470-484. e18, 2018 | 106 | 2018 |
The Vin-1 gene, identified by provirus insertional mutagenesis, is the cyclin D2. Z Hanna, M Jankowski, P Tremblay, X Jiang, A Milatovich, U Francke, ... Oncogene 8 (6), 1661-1666, 1993 | 104 | 1993 |
Huntingtin-associated protein 1 interacts with Ahi1 to regulate cerebellar and brainstem development in mice G Sheng, X Xu, YF Lin, CE Wang, J Rong, D Cheng, J Peng, X Jiang, ... The Journal of clinical investigation 118 (8), 2785-2795, 2008 | 93 | 2008 |
Ahi-1, a Novel Gene Encoding a Modular Protein with WD40-Repeat and SH3 Domains, Is Targeted by the Ahi-1 and Mis-2 Provirus Integrations X Jiang, Z Hanna, M Kaouass, L Girard, P Jolicoeur Journal of virology 76 (18), 9046-9059, 2002 | 92 | 2002 |
AHI-1 interacts with BCR-ABL and modulates BCR-ABL transforming activity and imatinib response of CML stem/progenitor cells LL Zhou, Y Zhao, A Ringrose, D DeGeer, E Kennah, AEJ Lin, G Sheng, ... The Journal of experimental medicine 205 (11), 2657-2671, 2008 | 90 | 2008 |
Evidence of an oncogenic role of aberrant TOX activation in cutaneous T-cell lymphoma Y Huang, MW Su, X Jiang, Y Zhou Blood, The Journal of the American Society of Hematology 125 (9), 1435-1443, 2015 | 82 | 2015 |
Unfulfilled promise of endostatin in a gene therapy-xenotransplant model of human acute lymphocytic leukemia W Eisterer, X Jiang, T Bachelot, R Pawliuk, C Abramovich, P Leboulch, ... Molecular Therapy 5 (4), 352-359, 2002 | 82 | 2002 |
Deficiency of SATB1 expression in Sézary cells causes apoptosis resistance by regulating FasL/CD95L transcription Y Wang, M Su, LL Zhou, P Tu, X Zhang, X Jiang, Y Zhou Blood, The Journal of the American Society of Hematology 117 (14), 3826-3835, 2011 | 72 | 2011 |