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Manoj Kumar
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Neurotoxic reactive astrocytes are induced by activated microglia
SA Liddelow, KA Guttenplan, LE Clarke, FC Bennett, CJ Bohlen, ...
Nature 541 (7638), 481-487, 2017
60832017
Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease
SP Yun, TI Kam, N Panicker, SM Kim, Y Oh, JS Park, SH Kwon, YJ Park, ...
Nature medicine 24 (7), 931-938, 2018
8482018
Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson’s disease
I Martin, JW Kim, BD Lee, HC Kang, JC Xu, H Jia, J Stankowski, MS Kim, ...
Cell 157 (2), 472-485, 2014
3022014
Activation of tyrosine kinase c-Abl contributes to α-synuclein–induced neurodegeneration
S Brahmachari, P Ge, SH Lee, D Kim, SS Karuppagounder, M Kumar, ...
The Journal of clinical investigation 126 (8), 2970-2988, 2016
1642016
Toward the human cellular microRNAome
MN McCall, MS Kim, M Adil, AH Patil, Y Lu, CJ Mitchell, P Leal-Rojas, ...
Genome research 27 (10), 1769-1781, 2017
1502017
Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson’s disease
N Panicker, TI Kam, H Wang, S Neifert, SC Chou, M Kumar, ...
Neuron 110 (15), 2422-2437. e9, 2022
822022
LRRK2 G2019S transgenic mice display increased susceptibility to 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-mediated neurotoxicity
SS Karuppagounder, Y Xiong, Y Lee, MC Lawless, D Kim, E Nordquist, ...
Journal of chemical neuroanatomy 76, 90-97, 2016
532016
Defects in mitochondrial biogenesis drive mitochondrial alterations in PARKIN-deficient human dopamine neurons
M Kumar, J Acevedo-Cintrón, A Jhaldiyal, H Wang, SA Andrabi, S Eacker, ...
Stem Cell Reports 15 (3), 629-645, 2020
512020
Parkin interacting substrate zinc finger protein 746 is a pathological mediator in Parkinson’s disease
S Brahmachari, S Lee, S Kim, C Yuan, SS Karuppagounder, P Ge, R Shi, ...
Brain 142 (8), 2380-2401, 2019
492019
Defects in mRNA translation in LRRK2-mutant hiPSC-derived dopaminergic neurons lead to dysregulated calcium homeostasis
JW Kim, X Yin, A Jhaldiyal, MR Khan, I Martin, Z Xie, T Perez-Rosello, ...
Cell stem cell 27 (4), 633-645. e7, 2020
412020
PARIS farnesylation prevents neurodegeneration in models of Parkinson’s disease
A Jo, Y Lee, TI Kam, SU Kang, S Neifert, SS Karuppagounder, R Khang, ...
Science translational medicine 13 (604), eaax8891, 2021
392021
Dymeclin deficiency causes postnatal microcephaly, hypomyelination and reticulum-to-Golgi trafficking defects in mice and humans
N Dupuis, A Fafouri, A Bayot, M Kumar, T Lecharpentier, G Ball, ...
Human molecular genetics 24 (10), 2771-2783, 2015
342015
Optimized derivation and functional characterization of 5-HT neurons from human embryonic stem cells
M Kumar, SK Kaushalya, P Gressens, S Maiti, S Mani
Stem cells and development 18 (4), 615-628, 2009
332009
A Novel RAB33B Mutation in Smith–McCort Dysplasia
N Dupuis, S Lebon, M Kumar, S Drunat, LM Graul‐Neumann, P Gressens, ...
Human mutation 34 (2), 283-286, 2013
322013
Conditional induction of Math1 specifies embryonic stem cells to cerebellar granule neuron lineage and promotes differentiation into mature granule neurons
R Srivastava, M Kumar, S Peineau, Z Csaba, S Mani, P Gressens, ...
Stem cells 31 (4), 652-665, 2013
242013
Neurospheres derived from human embryoid bodies treated with retinoic Acid show an increase in nestin and ngn2 expression that correlates with the proportion of tyrosine …
M Kumar, B Bagchi, SK Gupta, AS Meena, P Gressens, S Mani
Stem cells and development 16 (4), 667-682, 2007
222007
CMV promotor activity during ES cell differentiation: potential insight into embryonic stem cell differentiation
B Bagchi, M Kumar, S Mani
Cell biology international 30 (6), 505-513, 2006
212006
Endogenous cerebellar neurogenesis in adult mice with progressive ataxia
M Kumar, Z Csaba, S Peineau, R Srivastava, S Rasika, S Mani, ...
Annals of Clinical and Translational Neurology 1 (12), 968-981, 2014
182014
Deubiquitinase CYLD acts as a negative regulator of dopamine neuron survival in Parkinson’s disease
SK Pirooznia, H Wang, N Panicker, M Kumar, S Neifert, MA Dar, E Lau, ...
Science Advances 8 (13), eabh1824, 2022
112022
The c-Abl inhibitor IkT-148009 suppresses neurodegeneration in mouse models of heritable and sporadic Parkinson’s disease
SS Karuppagounder, H Wang, T Kelly, R Rush, R Nguyen, S Bisen, ...
Science translational medicine 15 (679), eabp9352, 2023
92023
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