In vitro digestion models to evaluate lipid based drug delivery systems; present status and current trends R Berthelsen, M Klitgaard, T Rades, A Müllertz Advanced Drug Delivery Reviews 142, 35-49, 2019 | 106 | 2019 |
Kolliphor surfactants affect solubilization and bioavailability of fenofibrate. Studies of in vitro digestion and absorption in rats R Berthelsen, R Holm, J Jacobsen, J Kristensen, B Abrahamsson, ... Molecular Pharmaceutics 12 (4), 1062-1071, 2015 | 53 | 2015 |
In Vitro Model Simulating Gastro-Intestinal Digestion in the Pediatric Population (Neonates and Young Infants) D Kamstrup, R Berthelsen, PJ Sassene, A Selen, A Müllertz AAPS PharmSciTech 18, 317-329, 2017 | 49 | 2017 |
The influence of drug and polymer particle size on the in situ amorphization using microwave irradiation NJ Hempel, MM Knopp, R Berthelsen, JA Zeitler, K Löbmann European Journal of Pharmaceutics and Biopharmaceutics 149, 77-84, 2020 | 29 | 2020 |
Combining in vitro and in silico methods for better prediction of surfactant effects on the absorption of poorly water soluble drugs—A fenofibrate case example R Berthelsen, E Sjögren, J Jacobsen, J Kristensen, R Holm, ... International journal of pharmaceutics 473 (1-2), 356-365, 2014 | 24 | 2014 |
The influence of temperature and viscosity of polyethylene glycol on the rate of microwave-induced in situ amorphization of celecoxib NJ Hempel, T Dao, MM Knopp, R Berthelsen, K Löbmann Molecules 26 (1), 110, 2020 | 23 | 2020 |
Studying furosemide solubilization using an in vitro model simulating gastrointestinal digestion and drug solubilization in neonates and young infants M Klitgaard, PJ Sassene, A Selen, A Müllertz, R Berthelsen European Journal of Pharmaceutical Sciences 109, 191-199, 2017 | 19 | 2017 |
Basolateral glycylsarcosine (Gly-Sar) transport in Caco-2 cell monolayers is pH dependent R Berthelsen, CU Nielsen, B Brodin Journal of Pharmacy and Pharmacology 65 (7), 970-979, 2013 | 19 | 2013 |
Estimating the oral absorption from self-nanoemulsifying drug delivery systems using an in vitro lipolysis-permeation method M Klitgaard, A Müllertz, R Berthelsen Pharmaceutics 13 (4), 489, 2021 | 17 | 2021 |
Convection-induced vs. microwave radiation-induced in situ drug amorphization NJ Hempel, MM Knopp, R Berthelsen, K Löbmann Molecules 25 (5), 1068, 2020 | 16 | 2020 |
Utilizing laser activation of photothermal plasmonic nanoparticles to induce on-demand drug amorphization inside a tablet NJ Hempel, P Merkl, S Asad, MM Knopp, R Berthelsen, CAS Bergstrom, ... Molecular Pharmaceutics 18 (6), 2254-2262, 2021 | 12 | 2021 |
Predicting oral absorption of fenofibrate in lipid-based drug delivery systems by combining in vitro lipolysis with the mucus-PVPA permeability model M Falavigna, M Klitgaard, R Berthelsen, A Müllertz, GE Flaten Journal of Pharmaceutical Sciences 110 (1), 208-216, 2021 | 12 | 2021 |
The use of glycerol as an enabling excipient for microwave-induced in situ drug amorphization NJ Hempel, F Morsch, MM Knopp, R Berthelsen, K Löbmann Journal of Pharmaceutical Sciences 110 (1), 155-163, 2021 | 11 | 2021 |
Physico-chemical characterization of aspirated and simulated human gastric fluids to study their influence on the intrinsic dissolution rate of cinnarizine PB Pedersen, R Berthelsen, T Rades, SA Jřrgensen, P Vilmann, ... International Journal of Pharmaceutics 622, 121856, 2022 | 10 | 2022 |
Adding a Gastric Step to the Intestinal In Vitro Digestion Model Improves the Prediction of Pharmacokinetic Data in Beagle Dogs of Two Lipid-Based Drug Delivery … M Klitgaard, S Beilles, PJ Sassene, R Berthelsen, A Müllertz Molecular Pharmaceutics 17 (9), 3214-3222, 2020 | 10 | 2020 |
Microwave induced in situ amorphisation facilitated by crystalline hydrates TP Holm, MM Knopp, K Löbmann, R Berthelsen European Journal of Pharmaceutical Sciences 163, 105858, 2021 | 9 | 2021 |
Supersaturated amorphous solid dispersions of celecoxib prepared in situ by microwave irradiation TP Holm, MM Knopp, R Berthelsen, K Löbmann International Journal of Pharmaceutics 626, 122115, 2022 | 7 | 2022 |
Microwave-induced in situ drug amorphization using a mixture of polyethylene glycol and polyvinylpyrrolidone NJ Hempel, MM Knopp, JA Zeitler, R Berthelsen, K Löbmann Journal of Pharmaceutical Sciences 110 (9), 3221-3229, 2021 | 7 | 2021 |
Evaluating side-by-side diffusion models for studying drug supersaturation in an absorptive environment: a case example of fenofibrate and felodipine JN Eliasen, R Berthelsen, AL Slot, A Müllertz Journal of Pharmacy and Pharmacology 72 (3), 371-384, 2020 | 7 | 2020 |
Direct visualizing of paracetamol immediate release tablet disintegration in vivo and in vitro F Fredholt, C Di Meo, S Sloth, A Müllertz, R Berthelsen European Journal of Pharmaceutics and Biopharmaceutics 180, 63-70, 2022 | 6 | 2022 |