Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection G Doitsh, NLK Galloway, X Geng, Z Yang, KM Monroe, O Zepeda, ... Nature 505 (7484), 509-514, 2014 | 1377 | 2014 |
IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV KM Monroe, Z Yang, JR Johnson, X Geng, G Doitsh, NJ Krogan, ... Science 343 (6169), 428-432, 2014 | 582 | 2014 |
Abortive HIV infection mediates CD4 T cell depletion and inflammation in human lymphoid tissue G Doitsh, M Cavrois, KG Lassen, O Zepeda, Z Yang, ML Santiago, ... Cell 143 (5), 789-801, 2010 | 537 | 2010 |
Dissecting how CD4 T cells are lost during HIV infection G Doitsh, WC Greene Cell host & microbe 19 (3), 280-291, 2016 | 285 | 2016 |
Hepatitis B virus pX targets TFIIB in transcription coactivation I Haviv, M Shamay, G Doitsh, Y Shaul Molecular and cellular biology 18 (3), 1562-1569, 1998 | 188 | 1998 |
Cell-to-cell transmission of HIV-1 is required to trigger pyroptotic death of lymphoid-tissue-derived CD4 T cells NLK Galloway, G Doitsh, KM Monroe, Z Yang, I Muñoz-Arias, DN Levy, ... Cell reports 12 (10), 1555-1563, 2015 | 173 | 2015 |
p53 binds and represses the HBV enhancer: an adjacent enhancer element can reverse the transcription effect of p53 A Ori, A Zauberman, G Doitsh, N Paran, M Oren, Y Shaul The EMBO journal, 1998 | 126 | 1998 |
Blood-derived CD4 T cells naturally resist pyroptosis during abortive HIV-1 infection I Muñoz-Arias, G Doitsh, Z Yang, S Sowinski, D Ruelas, WC Greene Cell host & microbe 18 (4), 463-470, 2015 | 115 | 2015 |
Enhancer I predominance in hepatitis B virus gene expression G Doitsh, Y Shaul Molecular and cellular biology, 2004 | 112 | 2004 |
Hepatitis B virus pX interacts with HBXAP, a PHD finger protein to coactivate transcription M Shamay, O Barak, G Doitsh, I Ben-Dor, Y Shaul Journal of Biological Chemistry 277 (12), 9982-9988, 2002 | 82 | 2002 |
A defective viral genome strategy elicits broad protective immunity against respiratory viruses Y Xiao, PV Lidsky, Y Shirogane, R Aviner, CT Wu, W Li, W Zheng, ... Cell 184 (25), 6037-6051. e14, 2021 | 46 | 2021 |
HBV transcription repression in response to genotoxic stress is p53-dependent and abrogated by pX G Doitsh, Y Shaul Oncogene 18 (52), 7506-7513, 1999 | 45 | 1999 |
Efficient delivery of lentiviral vectors into resting human CD4 T cells X Geng, G Doitsh, Z Yang, NLK Galloway, WC Greene Gene therapy 21 (4), 444-449, 2014 | 39 | 2014 |
A long HBV transcript encoding pX is inefficiently exported from the nucleus G Doitsh, Y Shaul Virology 309 (2), 339-349, 2003 | 37 | 2003 |
Distinct mechanisms regulate IL1B gene transcription in lymphoid CD4 T cells and monocytes SH Pulugulla, TA Packard, NLK Galloway, ZW Grimmett, G Doitsh, ... Cytokine 111, 373-381, 2018 | 30 | 2018 |
Correction: Corrigendum: Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection G Doitsh, NLK Galloway, X Geng, Z Yang, KM Monroe, O Zepeda, ... Nature 544 (7648), 124-124, 2017 | 16 | 2017 |
HIV-2 depletes CD4 T cells through pyroptosis despite Vpx-dependent degradation of SAMHD1 X Luo, E Herzig, G Doitsh, ZW Grimmett, I Muñoz-Arias, WC Greene Journal of Virology 93 (24), 10.1128/jvi. 00666-19, 2019 | 10 | 2019 |
Treatment Of HIV-1 Infection And AIDS G Doitsh, WC Greene, O Zepeda, N Galloway US Patent US20150343011A1, 2015 | 4* | 2015 |
Recombinant enteroviruses and uses thereof R Andino-Pavlovsky, X Yinghong, G Doitsh, R Nakamura, D Talbot US Patent App. 18/003,799, 2023 | | 2023 |
Constitutive Transcription of the ProIL-1β Gene in Human CCR5+ CD4 T Cells is Distinct from that of Monocytes SH Pulugulla, TA Packard, G Doitsh, J Adamik, DL Galson, WC Greene, ... The Journal of Immunology 198 (1_Supplement), 124.14-124.14, 2017 | | 2017 |