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Indira Prasadam
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An influenza virus-inspired polymer system for the timed release of siRNA
NP Truong, W Gu, I Prasadam, Z Jia, R Crawford, Y Xiao, MJ Monteiro
Nature communications 4 (1), 1902, 2013
1672013
ERK‐1/2 and p38 in the regulation of hypertrophic changes of normal articular cartilage chondrocytes induced by osteoarthritic subchondral osteoblasts
I Prasadam, S Van Gennip, T Friis, W Shi, R Crawford, Y Xiao
Arthritis & Rheumatism 62 (5), 1349-1360, 2010
1382010
Obesity, inflammation, and immune system in osteoarthritis
U Nedunchezhiyan, X Wu, I Prasadam
Frontiers in immunology 13, 907750, 2022
1202022
Cholesterol metabolism in pathogenesis of osteoarthritis disease
S Farnaghi, R Crawford, Y Xiao, I Prasadam
International journal of rheumatic diseases 20 (2), 131-140, 2017
1082017
Aggravation of ADAMTS and matrix metalloproteinase production and role of ERK1/2 pathway in the interaction of osteoarthritic subchondral bone osteoblasts and articular …
I Prasadam, R Crawford, Y Xiao
The Journal of rheumatology 39 (3), 621-634, 2012
1052012
Phenotypic characterization of osteoarthritic osteocytes from the sclerotic zones: a possible pathological role in subchondral bone sclerosis
A Jaiprakash, I Prasadam, JQ Feng, Y Liu, R Crawford, Y Xiao
International journal of biological sciences 8 (3), 406, 2012
1012012
Osteoarthritic cartilage chondrocytes alter subchondral bone osteoblast differentiation via MAPK signalling pathway involving ERK1/2
I Prasadam, T Friis, W Shi, S Van Gennip, R Crawford, Y Xiao
Bone 46 (1), 226-235, 2010
1002010
Saturated fatty acids induce development of both metabolic syndrome and osteoarthritis in rats
S Sekar, SR Shafie, I Prasadam, R Crawford, SK Panchal, L Brown, ...
Scientific reports 7 (1), 46457, 2017
962017
Obesity-associated metabolic syndrome spontaneously induces infiltration of pro-inflammatory macrophage in synovium and promotes osteoarthritis
ARJ Sun, SK Panchal, T Friis, S Sekar, R Crawford, L Brown, Y Xiao, ...
PloS one 12 (8), e0183693, 2017
942017
Protective effects of mitochondria‐targeted antioxidants and statins on cholesterolinduced osteoarthritis
S Farnaghi, I Prasadam, G Cai, T Friis, Z Du, R Crawford, X Mao, Y Xiao
The FASEB Journal 31 (1), 356-367, 2017
942017
Non-destructive evaluation of articular cartilage defects using near-infrared (NIR) spectroscopy in osteoarthritic rat models and its direct relation to Mankin score
I Afara, I Prasadam, R Crawford, Y Xiao, A Oloyede
Osteoarthritis and cartilage 20 (11), 1367-1373, 2012
942012
A comparative study of Sr-incorporated mesoporous bioactive glass scaffolds for regeneration of osteopenic bone defects
L Wei, J Ke, I Prasadam, RJ Miron, S Lin, Y Xiao, J Chang, C Wu, Y Zhang
Osteoporosis International 25, 2089-2096, 2014
912014
The microRNA expression signature on modified titanium implant surfaces influences genetic mechanisms leading to osteogenic differentiation
N Chakravorty, S Ivanovski, I Prasadam, R Crawford, A Oloyede, Y Xiao
Acta biomaterialia 8 (9), 3516-3523, 2012
792012
Combination of MEK-ERK inhibitor and hyaluronic acid has a synergistic effect on anti-hypertrophic and pro-chondrogenic activities in osteoarthritis treatment
I Prasadam, X Mao, W Shi, R Crawford, Y Xiao
Journal of molecular medicine 91, 369-380, 2013
682013
Inhibition of p38 pathway leads to OA-like changes in a rat animal model
I Prasadam, X Mao, Y Wang, W Shi, R Crawford, Y Xiao
Rheumatology 51 (5), 813-823, 2012
662012
Polymer nanocarrier system for endosome escape and timed release of siRNA with complete gene silencing and cell death in cancer cells
W Gu, Z Jia, NP Truong, I Prasadam, Y Xiao, MJ Monteiro
Biomacromolecules 14 (10), 3386-3389, 2013
612013
Pro-resolving lipid mediator ameliorates obesity induced osteoarthritis by regulating synovial macrophage polarisation
AR Sun, X Wu, B Liu, Y Chen, CW Armitage, A Kollipara, R Crawford, ...
Scientific reports 9 (1), 426, 2019
542019
Osteocyte-induced angiogenesis via VEGF–MAPK-dependent pathways in endothelial cells
I Prasadam, Y Zhou, Z Du, J Chen, R Crawford, Y Xiao
Molecular and cellular biochemistry 386, 15-25, 2014
542014
Exosomes extraction and identification
X Wu, SAA Showiheen, AR Sun, R Crawford, Y Xiao, X Mao, I Prasadam
Theranostics: Methods and Protocols, 81-91, 2019
532019
Impact of extracellular matrix derived from osteoarthritis subchondral bone osteoblasts on osteocytes: role of integrinβ1 and focal adhesion kinase signaling cues
I Prasadam, S Farnaghi, JQ Feng, W Gu, S Perry, R Crawford, Y Xiao
Arthritis research & therapy 15, 1-14, 2013
522013
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