Synthesis and evaluation of the antioxidant and anti-inflammatory activity of novel coumarin-3-aminoamides and their alpha-lipoic acid adducts G Melagraki, A Afantitis, O Igglessi-Markopoulou, A Detsi, M Koufaki, ... European journal of medicinal chemistry 44 (7), 3020-3026, 2009 | 358 | 2009 |
Design and synthesis of novel quinolinone-3-aminoamides and their α-lipoic acid adducts as antioxidant and anti-inflammatory agents A Detsi, D Bouloumbasi, KC Prousis, M Koufaki, G Athanasellis, ... Journal of medicinal chemistry 50 (10), 2450-2458, 2007 | 129 | 2007 |
Synthesis of chroman analogues of lipoic acid and evaluation of their activity against reperfusion arrhythmias M Koufaki, A Detsi, E Theodorou, C Kiziridi, T Calogeropoulou, ... Bioorganic & medicinal chemistry 12 (18), 4835-4841, 2004 | 80 | 2004 |
Novel potent inhibitors of lipid peroxidation with protective effects against reperfusion arrhythmias M Koufaki, T Calogeropoulou, A Detsi, A Roditis, AP Kourounakis, ... Journal of medicinal chemistry 44 (24), 4300-4303, 2001 | 65 | 2001 |
Design and synthesis of 1, 2-dithiolane derivatives and evaluation of their neuroprotective activity M Koufaki, C Kiziridi, F Nikoloudaki, MN Alexis Bioorganic & medicinal chemistry letters 17 (15), 4223-4227, 2007 | 64 | 2007 |
Chroman/catechol hybrids: synthesis and evaluation of their activity against oxidative stress induced cellular damage M Koufaki, E Theodorou, D Galaris, L Nousis, ES Katsanou, MN Alexis Journal of medicinal chemistry 49 (1), 300-306, 2006 | 64 | 2006 |
Synthesis of (Z)-4-Hydroxytamoxifen and (Z)-2-[4-[1-(p-Hydroxyphenyl)-2-phenyl]-1butenyl]phenoxyacetic Acid A Detsi, M Koufaki, T Calogeropoulou The Journal of organic chemistry 67 (13), 4608-4611, 2002 | 63 | 2002 |
Antileishmanial ring-substituted ether phospholipids N Avlonitis, E Lekka, A Detsi, M Koufaki, T Calogeropoulou, E Scoulica, ... Journal of medicinal chemistry 46 (5), 755-767, 2003 | 61 | 2003 |
5, 7, 8-Trimethyl-benzopyran and 5, 7, 8-Trimethyl-1, 4-benzoxazine Aminoamide Derivatives as Novel Antiarrhythmics against Ischemia− Reperfusion Injury EN Koini, P Papazafiri, A Vassilopoulos, M Koufaki, Z Horváth, I Koncz, ... Journal of medicinal chemistry 52 (8), 2328-2340, 2009 | 60 | 2009 |
Pharmacological pre-and post-conditioning agents: reperfusion-injury of the heart revisited I Andreadou, EK Iliodromitis, M Koufaki, DT Kremastinos Mini reviews in medicinal chemistry 8 (9), 952-959, 2008 | 58 | 2008 |
Design and synthesis of novel neuroprotective 1, 2-dithiolane/chroman hybrids M Koufaki, C Kiziridi, X Alexi, MN Alexis Bioorganic & medicinal chemistry 17 (17), 6432-6441, 2009 | 56 | 2009 |
Strategies in the design of prodrugs of anti-HIV agents T Calogeropoulou, A Detsi, E Lekkas, M Koufaki Current topics in medicinal chemistry 3 (13), 1467-1495, 2003 | 50 | 2003 |
Therapeutic applications of lipoic acid: a patent review (2011–2014) M Koufaki Expert opinion on therapeutic patents 24 (9), 993-1005, 2014 | 49 | 2014 |
Synthesis of tropolone derivatives and evaluation of their in vitro neuroprotective activity M Koufaki, E Theodorou, X Alexi, F Nikoloudaki, MN Alexis European journal of medicinal chemistry 45 (3), 1107-1112, 2010 | 45 | 2010 |
Microwave-assisted synthesis of 3, 5-disubstituted isoxazoles and evaluation of their anti-ageing activity M Koufaki, T Fotopoulou, M Kapetanou, GA Heropoulos, ES Gonos, ... European Journal of Medicinal Chemistry 83, 508-515, 2014 | 41 | 2014 |
Isoxazole substituted chromans against oxidative stress-induced neuronal damage M Koufaki, A Tsatsaroni, X Alexi, H Guerrand, S Zerva, MN Alexis Bioorganic & medicinal chemistry 19 (16), 4841-4850, 2011 | 41 | 2011 |
Ether phospholipid-AZT conjugates possessing anti-HIV and antitumor cell activity. Synthesis, conformational analysis, and study of their thermal effects on membrane bilayers T Mavromoustakos, T Calogeropoulou, M Koufaki, A Kolocouris, I Daliani, ... Journal of medicinal chemistry 44 (11), 1702-1709, 2001 | 41 | 2001 |
Bifunctional agents for reperfusion arrhythmias: Novel hybrid vitamin E/Class I antiarrhythmics M Koufaki, T Calogeropoulou, E Rekka, M Chryselis, P Papazafiri, ... Bioorganic & medicinal chemistry 11 (23), 5209-5219, 2003 | 39 | 2003 |
Multifunctional lipoic acid conjugates M Koufaki, A Detsi, C Kiziridi Current medicinal chemistry 16 (35), 4728-4742, 2009 | 38 | 2009 |
Synthesis and Antiretroviral Evaluation of New Alkoxy and Aryloxy Phosphate Derivatives of 3 ‘-Azido-3 ‘-deoxythymidine A Tsotinis, T Calogeropoulou, M Koufaki, C Souli, J Balzarini, E De Clercq, ... Journal of medicinal chemistry 39 (17), 3418-3422, 1996 | 37 | 1996 |