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Paride Liscio
Paride Liscio
Senior Research Scientist, Medicinal Chemistry, TES Pharma srl
Verificeret mail på tespharma.com
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De novo NAD+ synthesis enhances mitochondrial function and improves health
E Katsyuba, A Mottis, M Zietak, F De Franco, V van der Velpen, K Gariani, ...
Nature 563 (7731), 354-359, 2018
3572018
Targeting Wnt-driven cancers: Discovery of novel tankyrase inhibitors
M Ferri, P Liscio, A Carotti, S Asciutti, R Sardella, A Macchiarulo, ...
European Journal of Medicinal Chemistry 142, 506-522, 2017
552017
From polypharmacology to target specificity: the case of PARP inhibitors
P Liscio, E Camaioni, A Carotti, R Pellicciari, A Macchiarulo
Current Topics in Medicinal Chemistry 13 (23), 2939-2954, 2013
422013
α-Amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) inhibitors as novel modulators of de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis
R Pellicciari, P Liscio, N Giacchè, F De Franco, A Carotti, J Robertson, ...
Journal of medicinal chemistry 61 (3), 745-759, 2018
412018
Design, Synthesis, Crystallographic Studies, and Preliminary Biological Appraisal of New Substituted Triazolo[4,3-b]pyridazin-8-amine Derivatives as Tankyrase …
P Liscio, A Carotti, S Asciutti, T Karlberg, D Bellocchi, L Llacuna, ...
Journal of medicinal chemistry 57 (6), 2807-2812, 2014
402014
Concepts and Molecular Aspects in the Polypharmacology of PARP‐1 Inhibitors
D Passeri, E Camaioni, P Liscio, P Sabbatini, M Ferri, A Carotti, ...
ChemMedChem 11 (12), 1219-1226, 2016
332016
Discovery and characterization of novel potent PARP-1 inhibitors endowed with neuroprotective properties: From TIQ-A to HYDAMTIQ
R Pellicciari, E Camaioni, AM Gilbert, A Macchiarulo, JA Bikker, F Shah, ...
MedChemComm 2 (6), 559-565, 2011
222011
Scaffold hopping approach on the route to selective tankyrase inhibitors
P Liscio, A Carotti, S Asciutti, M Ferri, MM Pires, S Valloscuro, J Ziff, ...
European journal of medicinal chemistry 87, 611-623, 2014
192014
Investigating the allosteric reverse signalling of PARP inhibitors with microsecond molecular dynamic simulations and fluorescence anisotropy
JR Marchand, A Carotti, D Passeri, P Filipponi, P Liscio, E Camaioni, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1844 (10), 1765-1772, 2014
192014
Fragment based drug design and diversity-oriented synthesis of carboxylic acid isosteres
M Ferri, M Alunno, FA Greco, A Mammoli, G Saluti, A Carotti, R Sardella, ...
Bioorganic & Medicinal Chemistry 28 (22), 115731, 2020
102020
Structural basis of human dimeric α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase inhibition with TES-1025
M Cianci, N Giacchè, L Cialabrini, A Carotti, P Liscio, E Rosatelli, ...
Frontiers in Molecular Biosciences 9, 834700, 2022
32022
Therapeutic Potential of a Novel Poly (ADP-ribose) Polymerase Inhibitor, Hydamtiq, in Human Pancreatic and Colon Cancers
S Asciutti, E Camaioni, P Mong, N Biran, A Carotti, P Liscio, G Akiri, ...
Gastroenterology 144, 875-875, 2013
22013
Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase
R Pellicciari, P Liscio, N Giacche, F De Franco
US Patent App. 18/447,130, 2023
2023
Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase
R Pellicciari, P Liscio, N Giacche, F De Franco
US Patent App. 17/325,068, 2021
2021
Design, Synthesis, Crystallographic Studies, and Biological Appraisals of New Tankyrase Inhibitors.
E Camaioni, P Liscio, S Asciutti, A Carotti, A Macchiarulo, M Ferri, ...
Atti del Congresso, 2014
2014
Novel Wnt-Targeted Therapy Inhibitors for Hepatocellular Carcinoma
S Asciutti, E Ferretti, S Valloscuro, MM Pires, L Llacuna, D Esposito, ...
Gastroenterology 146, 690-690, 2014
2014
Targeting the FXR Nuclear Receptor through a Virtual Screening Approach
A Carotti, A Gioiello, A Macchiarulo, M Marinozzi, P Liscio, P Sabbatini, ...
Atti del XXIV Congresso Nazionale della Società Chimica Italiana, FAR-PO-12, 2011
2011
Synthesis, enantiomeric separation and preliminary evaluation of a series of new thioidantoine derivatives as inhibitors of indoleamine-2, 3-dioxygenase (IDO), a novel target …
P Liscio, E Camaioni, R Sardella, R Nuti, A Macchiarulo, G Pittelli, ...
XXX Convegno Interregionale Tosco Umbro Marchigiano Abruzzese TUMA 2011, 2011
2011
Synthesis, molecular modelling and preliminary evaluation of a series of new thioidantoine derivatives as inhibitors of indoleamine-2, 3-dioxygenase (IDO)
E Camaioni, G Pittelli, P Liscio, R Nuti, A Macchiarulo, R Sardella, ...
Hungarian-Austrian-Czech-German-Greek-Italian-Polish-Slovak-Slovenian Joint …, 2009
2009
Combined strategies toward the design and synthesis, of novel inhibitors of indoleamine-2, 3-dioxygenase (IDO)
E Camaioni, G Pittelli, P Liscio, R Nuti, A Macchiarulo, R Sardella, ...
XXIII Congresso Nazionale della Società Chimica Italiana, 2009
2009
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