| Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity M Soethoudt, U Grether, J Fingerle, TW Grim, F Fezza, L De Petrocellis, ... Nature communications 8 (1), 13958, 2017 | 308 | 2017 |
| Identification and quantification of a new family of peptide endocannabinoids (Pepcans) showing negative allosteric modulation at CB1 receptors M Bauer, A Chicca, M Tamborrini, D Eisen, R Lerner, B Lutz, O Poetz, ... Journal of biological chemistry 287 (44), 36944-36967, 2012 | 183 | 2012 |
| Evidence for bidirectional endocannabinoid transport across cell membranes A Chicca, J Marazzi, S Nicolussi, J Gertsch Journal of biological chemistry 287 (41), 34660-34682, 2012 | 163 | 2012 |
| Synergistic immunomopharmacological effects of N-alkylamides in Echinacea purpurea herbal extracts A Chicca, S Raduner, F Pellati, T Strompen, KH Altmann, R Schoop, ... International immunopharmacology 9 (7-8), 850-858, 2009 | 153 | 2009 |
| Cytotoxic effects of Echinacea root hexanic extracts on human cancer cell lines A Chicca, B Adinolfi, E Martinotti, S Fogli, MC Breschi, F Pellati, ... Journal of ethnopharmacology 110 (1), 148-153, 2007 | 98 | 2007 |
| Chemical probes to potently and selectively inhibit endocannabinoid cellular reuptake A Chicca, S Nicolussi, R Bartholomäus, M Blunder, A Aparisi Rey, ... Proceedings of the National Academy of Sciences 114 (25), E5006-E5015, 2017 | 97 | 2017 |
| Anticancer activity of anandamide in human cutaneous melanoma cells B Adinolfi, A Romanini, A Vanni, E Martinotti, A Chicca, S Fogli, P Nieri European journal of pharmacology 718 (1-3), 154-159, 2013 | 94 | 2013 |
| Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments F Petrelli, G Dallérac, L Pucci, C Calì, T Zehnder, S Sultan, S Lecca, ... Molecular psychiatry 25 (4), 732-749, 2020 | 89 | 2020 |
| β‐Caryophyllene protects against alcoholic steatohepatitis by attenuating inflammation and metabolic dysregulation in mice ZV Varga, C Matyas, K Erdelyi, R Cinar, D Nieri, A Chicca, BT Nemeth, ... British journal of pharmacology 175 (2), 320-334, 2018 | 89 | 2018 |
| The antinociceptive triterpene β‐amyrin inhibits 2‐arachidonoylglycerol (2‐AG) hydrolysis without directly targeting cannabinoid receptors A Chicca, J Marazzi, J Gertsch British journal of pharmacology 167 (8), 1596-1608, 2012 | 81 | 2012 |
| Functionalization of β-caryophyllene generates novel polypharmacology in the endocannabinoid system A Chicca, D Caprioglio, A Minassi, V Petrucci, G Appendino, ... ACS chemical biology 9 (7), 1499-1507, 2014 | 76 | 2014 |
| Pepcan-12 (RVD-hemopressin) is a CB2 receptor positive allosteric modulator constitutively secreted by adrenals and in liver upon tissue damage V Petrucci, A Chicca, S Glasmacher, J Paloczi, Z Cao, P Pacher, J Gertsch Scientific reports 7 (1), 9560, 2017 | 72 | 2017 |
| Uncovering the psychoactivity of a cannabinoid from liverworts associated with a legal high A Chicca, MA Schafroth, I Reynoso-Moreno, R Erni, V Petrucci, ... Science advances 4 (10), eaat2166, 2018 | 69 | 2018 |
| Cytotoxic activity of polyacetylenes and polyenes isolated from roots of Echinacea pallida A Chicca, F Pellati, B Adinolfi, A Matthias, I Massarelli, S Benvenuti, ... British journal of pharmacology 153 (5), 879-885, 2008 | 68 | 2008 |
| Cannabinoid derivatives induce cell death in pancreatic MIA PaCa-2 cells via a receptor-independent mechanism S Fogli, P Nieri, A Chicca, B Adinolfi, V Mariotti, P Iacopetti, MC Breschi, ... FEBS letters 580 (7), 1733-1739, 2006 | 64 | 2006 |
| Analysis of reptilian APOBEC1 suggests that RNA editing may not be its ancestral function F Severi, A Chicca, SG Conticello Molecular biology and evolution 28 (3), 1125-1129, 2011 | 61 | 2011 |
| Anti-proliferative activity of aguerin B and a new rare nor-guaianolide lactone isolated from the aerial parts of Centaurea deflexa A Chicca, M Tebano, B Adinolfi, K Ertugrul, G Flamini, P Nieri European journal of medicinal chemistry 46 (7), 3066-3070, 2011 | 52 | 2011 |
| Discovery of 1, 5-diphenylpyrazole-3-carboxamide derivatives as potent, reversible, and selective monoacylglycerol lipase (MAGL) inhibitors M Aghazadeh Tabrizi, PG Baraldi, S Baraldi, E Ruggiero, L De Stefano, ... Journal of medicinal chemistry 61 (3), 1340-1354, 2018 | 50 | 2018 |
| Optimization of a benzoylpiperidine class identifies a highly potent and selective reversible monoacylglycerol lipase (MAGL) inhibitor C Granchi, M Lapillo, S Glasmacher, G Bononi, C Licari, G Poli, ... Journal of medicinal chemistry 62 (4), 1932-1958, 2019 | 47 | 2019 |
| Elevated levels of endocannabinoids in chronic hepatitis C may modulate cellular immune response and hepatic stellate cell activation E Patsenker, P Sachse, A Chicca, MS Gachet, V Schneider, J Mattsson, ... International journal of molecular sciences 16 (4), 7057-7076, 2015 | 43 | 2015 |
