Sakari Kauppinen
Sakari Kauppinen
Professor, Center for RNA Medicine, Aalborg University
Bekræftet mail på dcm.aau.dk
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Treatment of HCV infection by targeting microRNA
HLA Janssen, HW Reesink, EJ Lawitz, S Zeuzem, M Rodriguez-Torres, ...
New England Journal of Medicine, 2013
19512013
Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection
RE Lanford, ES Hildebrandt-Eriksen, A Petri, R Persson, M Lindow, ...
Science 327 (5962), 198-201, 2010
18792010
LNA-mediated microRNA silencing in non-human primates
J Elmén, M Lindow, S Schütz, M Lawrence, A Petri, S Obad, M Lindholm, ...
Nature 452 (7189), 896-899, 2008
17692008
MicroRNA expression in zebrafish embryonic development
E Wienholds, WP Kloosterman, E Miska, E Alvarez-Saavedra, ...
Science 309 (5732), 310-311, 2005
17292005
Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/β-secretase expression
SS Hébert, K Horré, L Nicolaï, AS Papadopoulou, W Mandemakers, ...
PNAS USA 105 (17), 6415-6420, 2008
10772008
Sensitive and specific detection of microRNAs by northern blot analysis using LNA-modified oligonucleotide probes
A Válóczi, C Hornyik, N Varga, J Burgyán, S Kauppinen, Z Havelda
Nucleic Acids Research 32 (22), e175-e175, 2004
8152004
Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver
J Elmen, M Lindow, A Silahtaroglu, M Bak, M Christensen, ...
Nucleic Acids Research 36 (4), 1153-1162, 2008
7372008
In situ detection of miRNAs in animal embryos using LNA-modified oligonucleotide probes
WP Kloosterman, E Wienholds, E De Bruijn, S Kauppinen, RHA Plasterk
Nature Methods 3 (1), 27-29, 2005
6642005
Altered MicroRNA expression confined to specific epithelial cell subpopulations in breast cancer
LF Sempere, M Christensen, A Silahtaroglu, M Bak, CV Heath, ...
Cancer research 67 (24), 11612-11620, 2007
6352007
Silencing of microRNA families by seed-targeting tiny LNAs
S Obad, CO dos Santos, A Petri, M Heidenblad, O Broom, C Ruse, C Fu, ...
Nature Genetics 43 (4), 371-378, 2011
6242011
Diagnostic and prognostic microRNAs in stage II colon cancer
T Schepeler, JT Reinert, MS Ostenfeld, LL Christensen, AN Silahtaroglu, ...
Cancer Research 68 (15), 6416-6424, 2008
5582008
Development of microRNA therapeutics is coming of age
E van Rooij, S Kauppinen
EMBO molecular medicine, e201100899, 2014
5192014
MicroRNA expression in the adult mouse central nervous system
M Bak, A Silahtaroglu, M Møller, M Christensen, MF Rath, B Skryabin, ...
Rna 14 (3), 432-444, 2008
4902008
A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis
G Siegel, G Obernosterer, R Fiore, M Oehmen, S Bicker, M Christensen, ...
Nature Cell Biology 11 (6), 705-716, 2009
4872009
Inhibition of microRNA function by antimiR oligonucleotides
J Stenvang, A Petri, M Lindow, S Obad, S Kauppinen
Silence 3 (1), 1, 2012
4692012
LNA-modified oligonucleotides mediate specific inhibition of microRNA function
UA Ørom, S Kauppinen, AH Lund
Gene 372, 137-141, 2006
4612006
MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo
T Eskildsen, H Taipaleenmäki, J Stenvang, BM Abdallah, N Ditzel, ...
Proceedings of the National Academy of Sciences 108 (15), 6139-6144, 2011
4582011
Homologous domains in Trichoderma reesei cellulolytic enzymes: Gene sequence and expression of cellobiohydrolase II
TT Teeri, P Lehtovaara, S Kauppinen, I Salovuori, J Knowles
Gene 51 (1), 43-52, 1987
4431987
MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors
X Liu, LF Sempere, H Ouyang, VA Memoli, AS Andrew, Y Luo, ...
The Journal of clinical investigation 120 (4), 1298, 2010
4172010
Genomic profiling of microRNAs in bladder cancer: miR-129 is associated with poor outcome and promotes cell death in vitro
L Dyrskjøt, MS Ostenfeld, JB Bramsen, AN Silahtaroglu, P Lamy, ...
Cancer research 69 (11), 4851-4860, 2009
4042009
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Artikler 1–20