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Ellene Mashalidis
Ellene Mashalidis
Principal Scientist in Structural Biology and Biophysics, Pfizer
Verified email at pfizer.com
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Cited by
Year
BNT162b vaccines protect rhesus macaques from SARS-CoV-2
AB Vogel, I Kanevsky, Y Che, KA Swanson, A Muik, M Vormehr, LM Kranz, ...
Nature 592 (7853), 283-289, 2021
5852021
A three-stage biophysical screening cascade for fragment-based drug discovery
EH Mashalidis, P Śledź, S Lang, C Abell
Nature protocols 8 (11), 2309-2324, 2013
1742013
A prefusion SARS-CoV-2 spike RNA vaccine is highly immunogenic and prevents lung infection in non-human primates
AB Vogel, I Kanevsky, Y Che, KA Swanson, A Muik, M Vormehr, LM Kranz, ...
BioRxiv, 2020.09. 08.280818, 2020
1342020
GlcNAc-1-P-transferase–tunicamycin complex structure reveals basis for inhibition of N-glycosylation
J Yoo, EH Mashalidis, ACY Kuk, K Yamamoto, B Kaeser, S Ichikawa, ...
Nature structural & molecular biology 25 (3), 217-224, 2018
1252018
Structural insights into inhibition of lipid I production in bacterial cell wall synthesis
BC Chung, EH Mashalidis, T Tanino, M Kim, A Matsuda, J Hong, ...
Nature 533 (7604), 557-560, 2016
1072016
Crystal structure of the MOP flippase MurJ in an inward-facing conformation
ACY Kuk, EH Mashalidis, SY Lee
Nature structural & molecular biology 24 (2), 171-176, 2017
992017
Chemical logic of MraY inhibition by antibacterial nucleoside natural products
EH Mashalidis, B Kaeser, Y Terasawa, A Katsuyama, DY Kwon, K Lee, ...
Nature Communications 10 (1), 2917, 2019
562019
Disulfide-Dependent Self-Assembly of Adiponectin Octadecamers from Trimers and Presence of Stable Octadecameric Adiponectin Lacking Disulfide Bonds in Vitro
DB Briggs, CM Jones, EH Mashalidis, M Nunez, AC Hausrath, ...
Biochemistry 48 (51), 12345-12357, 2009
482009
BNT162b vaccines are immunogenic and protect non-human primates against SARS-CoV-2
AB Vogel, I Kanevsky, Y Che, KA Swanson, A Muik, M Vormehr, LM Kranz, ...
bioRxiv, 2020.12. 11.421008, 2020
222020
Molecular insights into the binding of coenzyme F420 to the conserved protein Rv1155 from Mycobacterium tuberculosis
EH Mashalidis, AG Gittis, A Tomczak, C Abell, CE Barry III, DN Garboczi
Protein Science 24 (5), 729-740, 2015
222015
Structures of bacterial MraY and human GPT provide insights into rational antibiotic design
EH Mashalidis, SY Lee
Journal of molecular biology 432 (18), 4946-4963, 2020
172020
Rv2607 from Mycobacterium tuberculosis is a pyridoxine 5′-phosphate oxidase with unusual substrate specificity
EH Mashalidis, T Mukherjee, P Śledź, D Matak-Vinković, H Boshoff, ...
PLoS One 6 (11), e27643, 2011
152011
High-resolution identification of human adiponectin oligomers and regulation by pioglitazone in type 2 diabetic patients
EH Mashalidis, DB Briggs, M Zhou, AM Vergara, JJ Chhun, RK Ellsworth, ...
Analytical biochemistry 437 (2), 150-160, 2013
142013
Biofragments: An Approach towards Predicting Protein Function Using Biologically Related Fragments and its Application to Mycobacterium tuberculosis CYP126
SA Hudson, EH Mashalidis, A Bender, KJ McLean, AW Munro, C Abell
Chembiochem 15 (4), 549-555, 2014
122014
Synthesis of macrocyclic nucleoside antibacterials and their interactions with MraY
T Nakaya, M Yabe, EH Mashalidis, T Sato, K Yamamoto, Y Hikiji, ...
Nature communications 13 (1), 7575, 2022
102022
Synthesis and evaluation of cyclopentane-based muraymycin analogs targeting MraY
SH Kwak, WY Lim, A Hao, EH Mashalidis, DY Kwon, P Jeong, MJ Kim, ...
European journal of medicinal chemistry 215, 113272, 2021
42021
Profound Treg perturbations correlate with COVID-19 severity (preprint)
S Galvan-Pena, J Leon, K Chowdhary, DA Michelson, B Vijaykumar, ...
12020
Discovery of SARS-CoV-2 papain-like protease (PLpro) inhibitors with efficacy in a murine infection model
MR Garnsey, MC Robinson, LT Nguyen, R Cardin, J Tillotson, ...
bioRxiv, 2024.01. 26.577395, 2024
2024
Discovery of orally active SARS-CoV-2 papain-like protease (PLpro) inhibitors
MR Garnsey, MC Robinson, LT Nguyen, R Cardin, J Tillotson, ...
2024
Discovery of orally active SARS-CoV-2 papain-like protease (PLpro) inhibitors (preprint)
MR Garnsey, MC Robinson, LT Nguyen, R Cardin, J Tillotson, ...
2024
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