| The medicinal chemistry in the era of machines and automation: recent advances in continuous flow technology A Gioiello, A Piccinno, AM Lozza, B Cerra Journal of medicinal chemistry 63 (13), 6624-6647, 2020 | 115 | 2020 |
| Steroids interfere with human carbonic anhydrase activity by using alternative binding mechanisms A Nocentini, A Bonardi, P Gratteri, B Cerra, A Gioiello, CT Supuran Journal of Enzyme Inhibition and Medicinal Chemistry 33 (1), 1453-1459, 2018 | 79 | 2018 |
| Beyond bile acids: targeting Farnesoid X Receptor (FXR) with natural and synthetic ligands A Carotti, M Marinozzi, C Custodi, B Cerra, R Pellicciari, A Gioiello, ... Current topics in medicinal chemistry 14 (19), 2129-2142, 2014 | 52 | 2014 |
| Bile acid derivatives as ligands of the farnesoid x receptor: molecular determinants for bile acid binding and receptor modulation A Gioiello, B Cerra, S Mostarda, C Guercini, R Pellicciari, A Macchiarulo Current topics in medicinal chemistry 14 (19), 2159-2174, 2014 | 51 | 2014 |
| Concepts and optimization strategies of experimental design in continuous-flow processing A Gioiello, V Mancino, P Filipponi, S Mostarda, B Cerra Journal of Flow Chemistry 6 (3), 167-180, 2016 | 40 | 2016 |
| Garcinoic acid is a natural and selective agonist of pregnane X receptor D Bartolini, F De Franco, P Torquato, R Marinelli, B Cerra, R Ronchetti, ... Journal of Medicinal Chemistry 63 (7), 3701-3712, 2020 | 36 | 2020 |
| Identification and quantification of oxo-bile acids in human faeces with liquid chromatography–mass spectrometry: A potent tool for human gut acidic sterolbiome studies P Franco, E Porru, J Fiori, A Gioiello, B Cerra, G Roda, C Caliceti, ... Journal of Chromatography a 1585, 70-81, 2019 | 35 | 2019 |
| Integrating multicomponent flow synthesis and computational approaches for the generation of a tetrahydroquinoline compound based library B Cerra, S Mostarda, C Custodi, A Macchiarulo, A Gioiello MedChemComm 7 (3), 439-446, 2016 | 27 | 2016 |
| Binding Mode and Structure-Activity Relationships of ITE as Aryl Hydrocarbon Receptor (AhR) Agonist D Dolciami, M Gargaro, B Cerra, G Scalisi, L Bagnoli, G Servillo, ... ChemMedChem 13 (3), 270-279, 2017 | 26 | 2017 |
| Exploiting Chemical Toolboxes for the Expedited Generation of Tetracyclic Quinolines as a Novel Class of PXR Agonists B Cerra, A Carotti, D Passeri, R Sardella, G Moroni, A Di Michele, ... ACS Medicinal Chemistry Letters 10 (4), 677-681, 2018 | 25 | 2018 |
| Synthesis, physicochemical properties, and biological activity of bile acids 3-glucuronides: Novel insights into bile acid signalling and detoxification AG Serena Mostarda, Daniela Passeri, Andrea Carotti, Bruno Cerra, Carolina ... European Journal of Medicinal Chemistry 144 (DOI: 10.1016/j.ejmech.2017.12 …, 2017 | 23* | 2017 |
| Selective Continuous Flow Synthesis of Hydroxy Lactones from Alkenoic Acids AG Bruno Cerra, Francesca Mangiavacchi, Claudio Santi, Anna Maria Lozza Reaction Chemistry & Engineering 2, 467-471, 2017 | 21 | 2017 |
| Continuous Flow Synthesis of 16-Dehydropregnenolone Acetate (16-DPA), a Key Synthon for Natural Steroids and Drugs AG Valentina Mancino, Bruno Cerra, Alessandro Piccinno Organic Process Research and Development 22 (5), 600-607, 2018 | 16 | 2018 |
| Synthesis of atypical bile acids for use as investigative tools for the genetic defect of 3β-hydroxy-Δ5-C27-steroid oxidoreductase deficiency A Gioiello, B Cerra, W Zhang, GP Vallerini, G Costantino, F De Franco, ... The Journal of Steroid Biochemistry and Molecular Biology 144, 348-360, 2014 | 14 | 2014 |
| Enantioselective HPLC Analysis to Assist the Chemical Exploration of Chiral Imidazolines RSAG Bruno Cerra, Antonio Macchiarulo, Andrea Carotti, Emidio Camaioni, Ina ... Molecules 25, 640, 2020 | 9 | 2020 |
| Selected cholesterol biosynthesis inhibitors produce accumulation of the intermediate FF-MAS that targets nucleus and activates LXRα in HepG2 cells RR Leonardo Gatticchi, Bruno Cerra, Paolo Scarpelli, Lara Macchioni ... Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids …, 2017 | 9 | 2017 |
| First Total Synthesis of Piperenol B and Configuration Revision of the Enantiomers Piperenol B and Uvarirufol A MDM Thomas C. Fischer, Bruno Cerra, Michael J. Fink, Florian Rudroff, Ernst ... European Journal of Organic Chemistry 2015 (7), 1464-1471, 2015 | 9 | 2015 |
| The Stone Guest: How Does pH Affect Binding Properties of PD‐1/PD‐L1 Inhibitors ? A Riccio, A Coletti, D Dolciami, A Mammoli, B Cerra, S Moretti, A Gioiello, ... ChemMedChem, 2020 | 8 | 2020 |
| Optimisation by Design of Experiment of Benzimidazol-2-One Synthesis under Flow Conditions S Mostarda, TG Maz, A Piccinno, B Cerra, E Banoglu Molecules 24, 2447, 2019 | 8 | 2019 |
| Integrating experimental and computational techniques to study chromatographic enantioresolutions of chiral tetrahydroindazole derivatives F Ianni, B Cerra, ST Shandiz, A Di Michele, G Saluti, R Galarini, A Gioiello, ... Journal of Chromatography A 1625, 461310, 2020 | 5 | 2020 |
Antimo GioielloDept. Pharmaceutical Sciences, University of PerugiaVerificeret mail på chimfarm.unipg.it
