| Dynamic and explainable machine learning prediction of mortality in patients in the intensive care unit: a retrospective study of high-frequency data in electronic patient records HC Thorsen-Meyer, AB Nielsen, AP Nielsen, BS Kaas-Hansen, P Toft, ... The Lancet Digital Health 2 (4), e179-e191, 2020 | 259 | 2020 |
| Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios S Besenbacher, S Liu, JMG Izarzugaza, J Grove, K Belling, J Bork-Jensen, ... Nature communications 6 (1), 5969, 2015 | 188 | 2015 |
| Sequencing and de novo assembly of 150 genomes from Denmark as a population reference L Maretty, JM Jensen, B Petersen, JA Sibbesen, S Liu, P Villesen, L Skov, ... Nature 548 (7665), 87-91, 2017 | 162 | 2017 |
| Establishment and characterization of models of chemotherapy resistance in colorectal cancer: Towards a predictive signature of chemoresistance NF Jensen, J Stenvang, MK Beck, B Hanáková, KC Belling, KN Do, B Viuff, ... Molecular oncology 9 (6), 1169-1185, 2015 | 121 | 2015 |
| Survival prediction in intensive-care units based on aggregation of long-term disease history and acute physiology: a retrospective study of the Danish National Patient … AB Nielsen, HC Thorsen-Meyer, K Belling, AP Nielsen, CE Thomas, ... The Lancet Digital Health 1 (2), e78-e89, 2019 | 109 | 2019 |
| MicroRNA expression profiling of carcinoma in situ cells of the testis GW Novotny, KC Belling, JB Bramsen, JE Nielsen, J Bork-Jensen, ... Endocrine-related cancer 19 (3), 365-379, 2012 | 101 | 2012 |
| Klinefelter syndrome comorbidities linked to increased X chromosome gene dosage and altered protein interactome activity K Belling, F Russo, AB Jensen, MD Dalgaard, D Westergaard, ... Human Molecular Genetics 26 (7), 1219-1229, 2017 | 92 | 2017 |
| Androgen receptor signalling in peritubular myoid cells is essential for normal differentiation and function of adult Leydig cells M Welsh, L Moffat, K Belling, LR De Franca, TM Segatelli, PTK Saunders, ... International journal of andrology 35 (1), 25-40, 2012 | 85 | 2012 |
| miRandola 2017: a curated knowledge base of non-invasive biomarkers F Russo, S Di Bella, F Vannini, G Berti, F Scoyni, HV Cook, A Santos, ... Nucleic acids research 46 (D1), D354-D359, 2018 | 78 | 2018 |
| Accurate genotyping across variant classes and lengths using variant graphs KA Sibbesen JA, Maretty L, The Danish Pan-Genome Consortium Nature Genetics 50, 1054-1059, 2018 | 70 | 2018 |
| Detection of serological biomarkers by proximity extension assay for detection of colorectal neoplasias in symptomatic individuals SB Thorsen, M Lundberg, A Villablanca, SLT Christensen, KC Belling, ... Journal of translational medicine 11, 1-13, 2013 | 65 | 2013 |
| Acquisition of docetaxel resistance in breast cancer cells reveals upregulation of ABCB1 expression as a key mediator of resistance accompanied by discrete … SN Hansen, D Westergaard, MBH Thomsen, M Vistesen, KN Do, L Fogh, ... Tumor Biology 36, 4327-4338, 2015 | 47 | 2015 |
| TIMP-1 increases expression and phosphorylation of proteins associated with drug resistance in breast cancer cells O Hekmat, S Munk, L Fogh, R Yadav, C Francavilla, H Horn, SØ Würtz, ... Journal of proteome research 12 (9), 4136-4151, 2013 | 45 | 2013 |
| Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli-and Leydig cells SB Winge, MD Dalgaard, KG Belling, JM Jensen, JE Nielsen, ... Cell Death & Disease 9 (6), 586, 2018 | 44 | 2018 |
| Analysis of 62 hybrid assembled human Y chromosomes exposes rapid structural changes and high rates of gene conversion SMH Skov L, Danish Pan Genome Consortium PLoS Genetics 13 (8), e1006834, 2017 | 39 | 2017 |
| Benchmarking the HLA typing performance of Polysolver and Optitype in 50 Danish parental trios IJMG Matey-Hernandez ML, Danish Pan Genome Consortium, Brunak S BMC Bioinformatics 19, 239, 2018 | 30* | 2018 |
| Discovery, genotyping and characterization of structural variation and novel sequence at single nucleotide resolution from de novo genome assemblies on a population scale WJ Liu S, Huang S, Rao J, Ye W, The Genome Denmark Consortium, Krogh A GigaScience 4, 64, 2015 | 24* | 2015 |
| TIMP1 overexpression mediates resistance of MCF-7 human breast cancer cells to fulvestrant and down-regulates progesterone receptor expression C Bjerre, L Vinther, KC Belling, SØ Würtz, R Yadav, U Lademann, ... Tumor Biology 34, 3839-3851, 2013 | 23 | 2013 |
| Assembly and analysis of 100 full MHC haplotypes from the Danish population JM Jensen, P Villesen, RM Friborg, T Mailund, S Besenbacher, ... Genome research 27 (9), 1597-1607, 2017 | 22 | 2017 |
| Comparison of global gene expression profiles of microdissected human foetal Leydig cells with their normal and hyperplastic adult equivalents G Lottrup, K Belling, H Leffers, JE Nielsen, MD Dalgaard, A Juul, ... MHR: Basic science of reproductive medicine 23 (5), 339-354, 2017 | 20 | 2017 |
Søren BrunakProfessor of Disease Systems Biology, University of CopenhagenVerificeret mail på cpr.ku.dk
