| Transcriptome and genome sequencing uncovers functional variation in humans T Lappalainen, M Sammeth, MR Friedländer, PAC ‘t Hoen, J Monlong, ... Nature 501 (7468), 506-511, 2013 | 2040 | 2013 |
| The genetic architecture of type 2 diabetes C Fuchsberger, J Flannick, TM Teslovich, A Mahajan, V Agarwala, ... Nature 536 (7614), 41-47, 2016 | 1236 | 2016 |
| Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: an exome sequencing study A Rauch, D Wieczorek, E Graf, T Wieland, S Endele, T Schwarzmayr, ... The Lancet 380 (9854), 1674-1682, 2012 | 1215 | 2012 |
| Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia A Freischmidt, T Wieland, B Richter, W Ruf, V Schaeffer, K Müller, ... Nature neuroscience 18 (5), 631-636, 2015 | 819 | 2015 |
| Enhanced Sarcoplasmic Reticulum Ca2+ Leak and Increased Na+-Ca2+ Exchanger Function Underlie Delayed Afterdepolarizations in Patients With Chronic … N Voigt, N Li, Q Wang, W Wang, AW Trafford, I Abu-Taha, Q Sun, ... Circulation 125 (17), 2059-2070, 2012 | 653 | 2012 |
| A deep proteome and transcriptome abundance atlas of 29 healthy human tissues D Wang, B Eraslan, T Wieland, B Hallström, T Hopf, DP Zolg, J Zecha, ... Molecular systems biology 15 (2), e8503, 2019 | 587 | 2019 |
| ADP receptors of platelets and their inhibition C Gachet Thrombosis and haemostasis 86 (07), 222-232, 2001 | 574 | 2001 |
| Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension F Beuschlein, S Boulkroun, A Osswald, T Wieland, HN Nielsen, ... Nature genetics 45 (4), 440-444, 2013 | 565 | 2013 |
| Mutations in the deubiquitinase gene USP8 cause Cushing's disease M Reincke, S Sbiera, A Hayakawa, M Theodoropoulou, A Osswald, ... Nature genetics 47 (1), 31-38, 2015 | 536 | 2015 |
| Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling M Felcht, R Luck, A Schering, P Seidel, K Srivastava, J Hu, A Bartol, ... The Journal of clinical investigation 122 (6), 1991-2005, 2012 | 497 | 2012 |
| Calmodulin mutations associated with recurrent cardiac arrest in infants L Crotti, CN Johnson, E Graf, GM De Ferrari, BF Cuneo, M Ovadia, ... Circulation 127 (9), 1009-1017, 2013 | 413 | 2013 |
| Constitutive activation of PKA catalytic subunit in adrenal Cushing's syndrome F Beuschlein, M Fassnacht, G Assié, D Calebiro, CA Stratakis, A Osswald, ... New England Journal of Medicine 370 (11), 1019-1028, 2014 | 411 | 2014 |
| How reliable are G-protein-coupled receptor antibodies? MC Michel, T Wieland, G Tsujimoto Naunyn-Schmiedeberg's archives of pharmacology 379, 385-388, 2009 | 368 | 2009 |
| Exome sequencing reveals de novo WDR45 mutations causing a phenotypically distinct, X-linked dominant form of NBIA TB Haack, P Hogarth, MC Kruer, A Gregory, T Wieland, T Schwarzmayr, ... The American journal of human genetics 91 (6), 1144-1149, 2012 | 350 | 2012 |
| Effect of predicted protein-truncating genetic variants on the human transcriptome MA Rivas, M Pirinen, DF Conrad, M Lek, EK Tsang, KJ Karczewski, ... Science 348 (6235), 666-669, 2015 | 341 | 2015 |
| Structure of Gαq-p63RhoGEF-RhoA complex reveals a pathway for the activation of RhoA by GPCRs S Lutz, A Shankaranarayanan, C Coco, M Ridilla, MR Nance, C Vettel, ... Science 318 (5858), 1923-1927, 2007 | 269 | 2007 |
| Reproducibility of high-throughput mRNA and small RNA sequencing across laboratories PAC 't Hoen, MR Friedländer, J Almlöf, M Sammeth, I Pulyakhina, ... Nature biotechnology 31 (11), 1015-1022, 2013 | 268 | 2013 |
| Mutations in DNMT1 cause autosomal dominant cerebellar ataxia, deafness and narcolepsy J Winkelmann, L Lin, B Schormair, BR Kornum, J Faraco, G Plazzi, ... Human molecular genetics 21 (10), 2205-2210, 2012 | 263 | 2012 |
| The guanine nucleotide exchange factor p63RhoGEF, a specific link between Gq/11-coupled receptor signaling and RhoA S Lutz, A Freichel-Blomquist, Y Yang, U Rumenapp, KH Jakobs, ... Journal of Biological Chemistry 280 (12), 11134-11139, 2005 | 261 | 2005 |
| Loss-of-function mutations in MGME1 impair mtDNA replication and cause multisystemic mitochondrial disease C Kornblum, TJ Nicholls, TB Haack, S Schöler, V Peeva, K Danhauser, ... Nature genetics 45 (2), 214-219, 2013 | 259 | 2013 |
