Christopher R. Jacobs
Christopher R. Jacobs
Professor of Biomedical Engineering, Columbia University
Bekræftet mail på columbia.edu
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A finite element model of the human knee joint for the study of tibio-femoral contact
TLH Donahue, ML Hull, MM Rashid, CR Jacobs
Journal of biomechanical engineering 124 (3), 273-280, 2002
5522002
Differential effect of steady versus oscillating flow on bone cells
CR Jacobs, CE Yellowley, BR Davis, Z Zhou, JM Cimbala, HJ Donahue
Journal of biomechanics 31 (11), 969-976, 1998
5431998
Molecular pathways mediating mechanical signaling in bone
J Rubin, C Rubin, CR Jacobs
Gene 367, 1-16, 2006
5082006
Osteopontin gene regulation by oscillatory fluid flow via intracellular calcium mobilization and activation of mitogen-activated protein kinase in MC3T3–E1 osteoblasts
J You, GC Reilly, X Zhen, CE Yellowley, Q Chen, HJ Donahue, ...
Journal of Biological Chemistry 276 (16), 13365-13371, 2001
4592001
Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism
AMD Malone, CT Anderson, P Tummala, RY Kwon, TR Johnston, ...
Proceedings of the National Academy of Sciences 104 (33), 13325-13330, 2007
4362007
Buffered platelet-rich plasma enhances mesenchymal stem cell proliferation and chondrogenic differentiation
A Mishra, P Tummala, A King, B Lee, M Kraus, V Tse, CR Jacobs
Tissue Engineering Part C: Methods 15 (3), 431-435, 2009
3902009
Substrate deformation levels associated with routine physical activity are less stimulatory to bone cells relative to loading-induced oscillatory fluid flow
J You, CE Yellowley, HJ Donahue, Y Zhang, Q Chen, CR Jacobs
Journal of biomechanical engineering 122 (4), 387-393, 2000
3592000
Osteocytes as mechanosensors in the inhibition of bone resorption due to mechanical loading
L You, S Temiyasathit, P Lee, CH Kim, P Tummala, W Yao, W Kingery, ...
Bone 42 (1), 172-179, 2008
3562008
Mechanically induced osteogenic differentiation–the role of RhoA, ROCKII and cytoskeletal dynamics
EJ Arnsdorf, P Tummala, RY Kwon, CR Jacobs
Journal of cell science 122 (4), 546-553, 2009
3502009
Oscillatory fluid flow affects human marrow stromal cell proliferation and differentiation
YJ Li, NN Batra, L You, SC Meier, IA Coe, CE Yellowley, CR Jacobs
Journal of Orthopaedic Research 22 (6), 1283-1289, 2004
2882004
Adaptive bone remodeling incorporating simultaneous density and anisotropy considerations
CR Jacobs, JC Simo, GS Beaupre, DR Carter
Journal of biomechanics 30 (6), 603-613, 1997
2711997
Functional gap junctions between osteocytic and osteoblastic cells
CE Yellowley, Z Li, Z Zhou, CR Jacobs, HJ Donahue
Journal of bone and mineral research 15 (2), 209-217, 2000
2662000
How the stiffness of meniscal attachments and meniscal material properties affect tibio-femoral contact pressure computed using a validated finite element model of the human …
TLH Donahue, ML Hull, MM Rashid, CR Jacobs
Journal of biomechanics 36 (1), 19-34, 2003
2542003
The role of mechanical signals in regulating chondrogenesis and osteogenesis of mesenchymal stem cells
DJ Kelly, CR Jacobs
Birth Defects Research Part C: Embryo Today: Reviews 90 (1), 75-85, 2010
2292010
Substance P signaling contributes to the vascular and nociceptive abnormalities observed in a tibial fracture rat model of complex regional pain syndrome type I
TZ Guo, SC Offley, EA Boyd, CR Jacobs, WS Kingery
Pain 108 (1-2), 95-107, 2004
1902004
Numerical instabilities in bone remodeling simulations: the advantages of a node-based finite element approach
CR Jacobs, ME Levenston, GS Beaupré, JC Simo, DR Carter
Journal of biomechanics 28 (4), 449-451, 1995
1891995
The consequences of anterior femoral notching in total knee arthroplasty: a biomechanical study
ML Lesh, DJ Schneider, G Deol, B Davis, CR Jacobs, VD Pelligrini Jr
JBJS 82 (8), 1096, 2000
1872000
Non-canonical Wnt signaling and N-cadherin related β-catenin signaling play a role in mechanically induced osteogenic cell fate
EJ Arnsdorf, P Tummala, CR Jacobs
PloS one 4 (4), e5388, 2009
1782009
Oscillatory fluid flow-induced shear stress decreases osteoclastogenesis through RANKL and OPG signaling
CH Kim, L You, CE Yellowley, CR Jacobs
Bone 39 (5), 1043-1047, 2006
1742006
Osteocyte mechanobiology and pericellular mechanics
CR Jacobs, S Temiyasathit, AB Castillo
Annual review of biomedical engineering 12, 369-400, 2010
1722010
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Artikler 1–20