Følg
Helene Faustrup Kildegaard
Helene Faustrup Kildegaard
Novo Nordisk
Verificeret mail på faustrup.dk
Titel
Citeret af
Citeret af
År
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins
N Mailand, S Bekker-Jensen, H Faustrup, F Melander, J Bartek, C Lukas, ...
Cell 131 (5), 887-900, 2007
13532007
Site-specific integration in CHO cells mediated by CRISPR/Cas9 and homology-directed DNA repair pathway
JS Lee, TB Kallehauge, LE Pedersen, HF Kildegaard
Scientific reports 5, 8572, 2015
2452015
A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism
H Hefzi, KS Ang, M Hanscho, A Bordbar, D Ruckerbauer, M Lakshmanan, ...
Cell Systems 3 (5), 434-443. e8, 2016
2422016
Accelerating genome editing in CHO cells using CRISPR Cas9 and CRISPy, a web‐based target finding tool
C Ronda, LE Pedersen, HG Hansen, TB Kallehauge, MJ Betenbaugh, ...
Biotechnology and bioengineering 111 (8), 1604-1616, 2014
2232014
The emerging CHO systems biology era: harnessing the ‘omics revolution for biotechnology
HF Kildegaard, D Baycin-Hizal, NE Lewis, MJ Betenbaugh
Current opinion in biotechnology 24 (6), 1102-1107, 2013
1972013
Impact of CHO metabolism on cell growth and protein production: an overview of toxic and inhibiting metabolites and nutrients
S Pereira, HF Kildegaard, MR Andersen
Biotechnology journal 13 (3), 1700499, 2018
1762018
USP7 counteracts SCFβTrCP-but not APCCdh1-mediated proteolysis of Claspin
H Faustrup, S Bekker-Jensen, J Bartek, J Lukas, N Mailand
The Journal of cell biology 184 (1), 13-19, 2009
1612009
One‐step generation of triple knockout CHO cell lines using CRISPR/Cas9 and fluorescent enrichment
LM Grav, JS Lee, S Gerling, TB Kallehauge, AH Hansen, S Kol, GM Lee, ...
Biotechnology journal 10 (9), 1446-1456, 2015
1532015
CRISPR/Cas9‐mediated genome engineering of CHO cell factories: Application and perspectives
JS Lee, LM Grav, NE Lewis, H Faustrup Kildegaard
Biotechnology journal 10 (7), 979-994, 2015
1412015
Cell Factory Engineering
AM Davy, HF Kildegaard, MR Andersen
Cell Systems 4 (3), 262-275, 2017
1342017
Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion
JM Gutierrez, A Feizi, S Li, TB Kallehauge, H Hefzi, LM Grav, D Ley, ...
Nature Communications 11 (1), 1-10, 2020
1082020
A Markov chain model for N-linked protein glycosylation–towards a low-parameter tool for model-driven glycoengineering
PN Spahn, AH Hansen, HG Hansen, J Arnsdorf, HF Kildegaard, NE Lewis
Metabolic engineering 33, 52-66, 2016
1052016
Glycoengineering of Chinese hamster ovary cells for enhanced erythropoietin N‐glycan branching and sialylation
B Yin, Y Gao, C Chung, S Yang, E Blake, MC Stuczynski, J Tang, ...
Biotechnology and bioengineering 112 (11), 2343-2351, 2015
972015
Multiplex secretome engineering enhances recombinant protein production and purity
S Kol, D Ley, T Wulff, M Decker, J Arnsdorf, S Schoffelen, AH Hansen, ...
Nature communications 11 (1), 1-10, 2020
902020
Improving the secretory capacity of Chinese hamster ovary cells by ectopic expression of effector genes: Lessons learned and future directions
HG Hansen, N Pristovšek, HF Kildegaard, GM Lee
Biotechnology advances 35 (1), 64-76, 2017
852017
Accelerated homology‐directed targeted integration of transgenes in Chinese hamster ovary cells via CRISPR/Cas9 and fluorescent enrichment
JS Lee, LM Grav, LE Pedersen, GM Lee, HF Kildegaard
Biotechnology and bioengineering 113 (11), 2518-2523, 2016
832016
Minimizing clonal variation during mammalian cell line engineering for improved systems biology data generation
LM Grav, D Sergeeva, JS Lee, I Marin de Mas, NE Lewis, MR Andersen, ...
ACS synthetic biology 7 (9), 2148-2159, 2018
702018
Glycoprofiling effects of media additives on IgG produced by CHO cells in fed‐batch bioreactors
HF Kildegaard, Y Fan, JW Sen, B Larsen, MR Andersen
Biotechnology and bioengineering 113 (2), 359-366, 2016
702016
Ribosome profiling-guided depletion of an mRNA increases cell growth rate and protein secretion
TB Kallehauge, S Li, LE Pedersen, TK Ha, D Ley, MR Andersen, ...
Scientific Reports 7, 40388, 2017
622017
Mitigating Clonal Variation in Recombinant Mammalian Cell Lines
JS Lee, HF Kildegaard, NE Lewis, GM Lee
Trends in biotechnology, 2019
592019
Systemet kan ikke foretage handlingen nu. Prøv igen senere.
Artikler 1–20