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Ardy van Helvoort
Ardy van Helvoort
Senior Director R&I Nutritional Physiology & Functional Nutrients; Associate Professor Medical
Verificeret mail på danone.com
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MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine
A van Helvoort, AJ Smith, H Sprong, I Fritzsche, AH Schinkel, P Borst, ...
Cell 87 (3), 507-517, 1996
11101996
ABC transporters in lipid transport
P Borst, N Zelcer, A Van Helvoort
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2000
3822000
MDR3 P-glycoprotein, a phosphatidylcholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with nucleotide trapping
AJ Smith, A van Helvoort, G van Meer, K Szabó, E Welker, G Szakács, ...
Journal of Biological Chemistry 275 (31), 23530-23539, 2000
3572000
Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies
GL Scheffer, M Kool, M Heijn, M de Haas, ACLM Pijnenborg, J Wijnholds, ...
Cancer research 60 (18), 5269-5277, 2000
2922000
Muscle protein synthesis in cancer patients can be stimulated with a specially formulated medical food
NEP Deutz, A Safar, S Schutzler, R Memelink, A Ferrando, H Spencer, ...
Clinical nutrition 30 (6), 759-768, 2011
2562011
The human multidrug resistance protein MRP1 translocates sphingolipid analogs across the plasma membrane
RJ Raggers, A Helvoort, R Evers, G Meer
Journal of cell science 112 (3), 415-422, 1999
1821999
Randomized, double-blind, placebo-controlled crossover study in men with prostate cancer and rising PSA: effectiveness of a dietary supplement
FH Schröder, MJ Roobol, ER Boevé, R de Mutsert, ...
European urology 48 (6), 922-931, 2005
1682005
A randomized clinical trial investigating the efficacy of targeted nutrition as adjunct to exercise training in COPD
C Bool, E Rutten, A Helvoort, FME Franssen, EFM Wouters, AMWJ Schols
Journal of Cachexia, Sarcopenia and Muscle 8 (5), 748–758, 2017
1502017
Direct effects of doxorubicin on skeletal muscle contribute to fatigue
K Van Norren, A Van Helvoort, JM Argilés, S Van Tuijl, K Arts, M Gorselink, ...
British journal of cancer 100 (2), 311-314, 2009
1402009
Transport of sphingomyelin to the cell surface is inhibited by brefeldin A and in mitosis, where C6-NBD-sphingomyelin is translocated across the plasma membrane by a multidrug …
A Helvoort, ML Giudici, M Thielemans, G Meer
Journal of Cell Science 110 (1), 75-83, 1997
1361997
Dietary supplementation with a specific combination of high protein, leucine, and fish oil improves muscle function and daily activity in tumour-bearing cachectic mice
K Van Norren, D Kegler, JM Argiles, Y Luiking, M Gorselink, A Laviano, ...
British journal of cancer 100 (5), 713-722, 2009
1272009
Conversion of diacylglycerol to phosphatidylcholine on the basolateral surface of epithelial (Madin-Darby canine kidney) cells. Evidence for the reverse action of a …
A Van Helvoort, W Van't Hof, T Ritsema, A Sandra, G Van Meer
Journal of Biological Chemistry 269 (3), 1763-1769, 1994
1171994
Supplementation with a Fish Oil-Enriched, High-Protein Medical Food Leads to Rapid Incorporation of EPA into White Blood Cells and Modulates Immune Responses within One Week in …
J Faber, M Berkhout, AP Vos, JWC Sijben, PC Calder, J Garssen, ...
The Journal of nutrition 141 (5), 964-970, 2011
1012011
Importance of glycolipid synthesis for butyric acid-induced sensitization to shiga toxin and intracellular sorting of toxin in A431 cells.
K Sandvig, O Garred, A Van Helvoort, G Van Meer, B Van Deurs
Molecular Biology of the Cell 7 (9), 1391-1404, 1996
911996
Mice without phosphatidylcholine transfer protein have no defects in the secretion of phosphatidylcholine into bile or into lung airspaces
A van Helvoort, A de Brouwer, R Ottenhoff, JFHM Brouwers, J Wijnholds, ...
Proceedings of the National Academy of Sciences 96 (20), 11501-11506, 1999
901999
Psychological co-morbidities in COPD: targeting systemic inflammation, a benefit for both?
CE Pelgrim, JD Peterson, HR Gosker, AMWJ Schols, A van Helvoort, ...
European journal of pharmacology 842, 99-110, 2019
722019
Gut microbiota and short‐chain fatty acid alterations in cachectic cancer patients
J Ubachs, J Ziemons, Z Soons, R Aarnoutse, DPJ van Dijk, J Penders, ...
Journal of cachexia, sarcopenia and muscle 12 (6), 2007-2021, 2021
692021
Low levels of branched chain amino acids, eicosapentaenoic acid and micronutrients are associated with low muscle mass, strength and function in community-dwelling older adults
S Ter Borg, YC Luiking, A van Helvoort, Y Boirie, J Schols, C De Groot
The Journal of nutrition, health and aging 23 (1), 27-34, 2019
692019
Fish oil LC-PUFAs do not affect blood coagulation parameters and bleeding manifestations: Analysis of 8 clinical studies with selected patient groups on omega-3-enriched …
S Jeansen, RF Witkamp, JA Garthoff, A van Helvoort, PC Calder
Clinical nutrition 37 (3), 948-957, 2018
592018
Beneficial immune modulatory effects of a specific nutritional combination in a murine model for cancer cachexia
J Faber, P Vos, D Kegler, K Van Norren, JM Argiles, A Laviano, J Garssen, ...
British journal of cancer 99 (12), 2029-2036, 2008
592008
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