A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae A Hammond, R Galizi, K Kyrou, A Simoni, C Siniscalchi, D Katsanos, ... Nature biotechnology 34 (1), 78-83, 2016 | 1438 | 2016 |
A CRISPR–Cas9 gene drive targeting doublesex causes complete population suppression in caged Anopheles gambiae mosquitoes K Kyrou, AM Hammond, R Galizi, N Kranjc, A Burt, AK Beaghton, T Nolan, ... Nature biotechnology 36 (11), 1062-1066, 2018 | 862 | 2018 |
Highly evolvable malaria vectors: The genomes of 16 Anopheles mosquitoes DE Neafsey, RM Waterhouse, MR Abai, SS Aganezov, MA Alekseyev, ... Science 347 (6217), 1258522, 2015 | 621 | 2015 |
Stable germline transformation of the malaria mosquito Anopheles stephensi F Catteruccia, T Nolan, TG Loukeris, C Blass, C Savakis, FC Kafatos, ... Nature 405 (6789), 959-962, 2000 | 508 | 2000 |
Bee venom phospholipase inhibits malaria parasite development in transgenic mosquitoes LA Moreira, J Ito, A Ghosh, M Devenport, H Zieler, EG Abraham, ... Journal of Biological Chemistry 277 (43), 40839-40843, 2002 | 347 | 2002 |
The creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito AM Hammond, K Kyrou, M Bruttini, A North, R Galizi, X Karlsson, N Kranjc, ... PLoS genetics 13 (10), e1007039, 2017 | 304 | 2017 |
piggyBac-mediated germline transformation of the malaria mosquito Anopheles stephensi using the red fluorescent protein dsRED as a selectable marker T Nolan, TM Bower, AE Brown, A Crisanti, F Catteruccia Journal of Biological Chemistry 277 (11), 8759-8762, 2002 | 216 | 2002 |
A male-biased sex-distorter gene drive for the human malaria vector Anopheles gambiae A Simoni, AM Hammond, AK Beaghton, R Galizi, C Taxiarchi, K Kyrou, ... Nature biotechnology 38 (9), 1054-1060, 2020 | 209 | 2020 |
A CRISPR-Cas9 sex-ratio distortion system for genetic control R Galizi, A Hammond, K Kyrou, C Taxiarchi, F Bernardini, SM O’Loughlin, ... Scientific reports 6 (1), 31139, 2016 | 209 | 2016 |
A comprehensive gene expression atlas of sex- and tissue-specificity in the malaria vector, Anopheles gambiae DA Baker, T Nolan, B Fischer, A Pinder, A Crisanti, S Russell BMC genomics 12, 1-12, 2011 | 207 | 2011 |
Toward Anopheles transformation: Minos element activity in anopheline cells and embryos F Catteruccia, T Nolan, C Blass, HM Müller, A Crisanti, FC Kafatos, ... Proceedings of the National Academy of Sciences 97 (5), 2157-2162, 2000 | 180 | 2000 |
Regulating the expression of gene drives is key to increasing their invasive potential and the mitigation of resistance A Hammond, X Karlsson, I Morianou, K Kyrou, A Beaghton, M Gribble, ... PLoS genetics 17 (1), e1009321, 2021 | 141* | 2021 |
The post-transcriptional gene silencing machinery functions independently of DNA methylation to repress a LINE1-like retrotransposon in Neurospora crassa T Nolan, L Braccini, G Azzalin, A De Toni, G Macino, C Cogoni Nucleic acids research 33 (5), 1564-1573, 2005 | 128 | 2005 |
Gene-drive suppression of mosquito populations in large cages as a bridge between lab and field A Hammond, P Pollegioni, T Persampieri, A North, R Minuz, A Trusso, ... Nature Communications 12 (1), 4589, 2021 | 110 | 2021 |
Radical remodeling of the Y chromosome in a recent radiation of malaria mosquitoes AB Hall, PA Papathanos, A Sharma, C Cheng, OS Akbari, L Assour, ... Proceedings of the National Academy of Sciences 113 (15), E2114-E2123, 2016 | 107 | 2016 |
Tools for Anopheles gambiae Transgenesis G Volohonsky, O Terenzi, J Soichot, DA Naujoks, T Nolan, N Windbichler, ... G3: Genes, Genomes, Genetics 5 (6), 1151-1163, 2015 | 106 | 2015 |
Transcription regulation of sex-biased genes during ontogeny in the malaria vector Anopheles gambiae K Magnusson, AM Mendes, N Windbichler, PA Papathanos, T Nolan, ... PloS one 6 (6), e21572, 2011 | 90 | 2011 |
Developing transgenic Anopheles mosquitoes for the sterile insect technique T Nolan, P Papathanos, N Windbichler, K Magnusson, J Benton, ... Genetica 139, 33-39, 2011 | 89 | 2011 |
Phenylalanine metabolism regulates reproduction and parasite melanization in the malaria mosquito S Fuchs, V Behrends, JG Bundy, A Crisanti, T Nolan PloS one 9 (1), e84865, 2014 | 88 | 2014 |
Toward the definition of efficacy and safety criteria for advancing gene drive-modified mosquitoes to field testing SL James, JM Marshall, GK Christophides, FO Okumu, T Nolan Vector-Borne and Zoonotic Diseases 20 (4), 237-251, 2020 | 78 | 2020 |