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Dr. Eric Lechman
Dr. Eric Lechman
University of Pittsburgh
Verificeret mail på uhnres.utoronto.ca
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Stem cell gene expression programs influence clinical outcome in human leukemia
K Eppert, K Takenaka, ER Lechman, L Waldron, B Nilsson, P Van Galen, ...
Nature medicine 17 (9), 1086-1093, 2011
11542011
Exosomes derived from IL-10-treated dendritic cells can suppress inflammation and collagen-induced arthritis
SH Kim, ER Lechman, N Bianco, R Menon, A Keravala, J Nash, Z Mi, ...
The Journal of Immunology 174 (10), 6440-6448, 2005
4392005
Comparison of human cord blood engraftment between immunocompromised mouse strains
SP McDermott, K Eppert, ER Lechman, M Doedens, JE Dick
Blood, The Journal of the American Society of Hematology 116 (2), 193-200, 2010
3612010
Direct adenovirus-mediated gene transfer of interleukin 1 and tumor necrosis factor α soluble receptors to rabbit knees with experimental arthritis has local and distal anti …
SC Ghivizzani, ER Lechman, R Kang, C Tio, J Kolls, CH Evans, ...
Proceedings of the National Academy of Sciences 95 (8), 4613-4618, 1998
3471998
A distinctive DNA damage response in human hematopoietic stem cells reveals an apoptosis-independent role for p53 in self-renewal
M Milyavsky, OI Gan, M Trottier, M Komosa, O Tabach, F Notta, ...
Cell stem cell 7 (2), 186-197, 2010
3232010
miR-126 regulates distinct self-renewal outcomes in normal and malignant hematopoietic stem cells
ER Lechman, B Gentner, SWK Ng, EM Schoof, P van Galen, JA Kennedy, ...
Cancer cell 29 (2), 214-228, 2016
2872016
Adenoviral transfer of the viral IL-10 gene periarticularly to mouse paws suppresses development of collagen-induced arthritis in both injected and uninjected paws
JD Whalen, EL Lechman, CA Carlos, K Weiss, I Kovesdi, JC Glorioso, ...
The journal of immunology 162 (6), 3625-3632, 1999
2611999
Exosomes derived from genetically modified DC expressing FasL are anti-inflammatory and immunosuppressive
SH Kim, N Bianco, R Menon, ER Lechman, WJ Shufesky, AE Morelli, ...
Molecular therapy 13 (2), 289-300, 2006
2602006
Attenuation of miR-126 activity expands HSC in vivo without exhaustion
ER Lechman, B Gentner, P van Galen, A Giustacchini, M Saini, ...
Cell stem cell 11 (6), 799-811, 2012
2322012
Quantitative single-cell proteomics as a tool to characterize cellular hierarchies
EM Schoof, B Furtwängler, N Üresin, N Rapin, S Savickas, C Gentil, ...
Nature communications 12 (1), 3341, 2021
2262021
Identification of hematopoietic stem cell–specific miRNAs enables gene therapy of globoid cell leukodystrophy
B Gentner, I Visigalli, H Hiramatsu, E Lechman, S Ungari, A Giustacchini, ...
Science translational medicine 2 (58), 58ra84-58ra84, 2010
2242010
Direct adenoviral gene transfer of viral IL-10 to rabbit knees with experimental arthritis ameliorates disease in both injected and contralateral control knees
ER Lechman, D Jaffurs, SC Ghivizzani, A Gambotto, I Kovesdi, Z Mi, ...
The Journal of Immunology 163 (4), 2202-2208, 1999
1851999
Constitutive intra-articular expression of human IL-1 beta following gene transfer to rabbit synovium produces all major pathologies of human rheumatoid arthritis.
SC Ghivizzani, R Kang, HI Georgescu, ER Lechman, D Jaffurs, JM Engle, ...
Journal of immunology (Baltimore, Md.: 1950) 159 (7), 3604-3612, 1997
1781997
Adenovirus‐mediated gene transfer of insulin‐like growth factor 1 stimulates proteoglycan synthesis in rabbit joints
Z Mi, SC Ghivizzani, ER Lechman, D Jaffurs, JC Glorioso, CH Evans, ...
Arthritis & Rheumatism: Official Journal of the American College of …, 2000
1482000
Intra-articular delivery of a herpes simplex virus IL-1Ra gene vector reduces inflammation in a rabbit model of arthritis
T Oligino, SC Ghivizzani, D Wolfe, ER Lechman, D Krisky, Z Mi, CH Evans, ...
Gene therapy 6 (10), 1713-1720, 1999
1441999
Adverse effects of adenovirus-mediated gene transfer of human transforming growth factor beta 1 into rabbit knees
Z Mi, SC Ghivizzani, E Lechman, JC Glorioso, CH Evans, PD Robbins
Arthritis Res Ther 5, 1-8, 2003
1432003
Ex vivo gene delivery of IL-1Ra and soluble TNF receptor confers a distal synergistic therapeutic effect in antigen-induced arthritis
SH Kim, ER Lechman, S Kim, J Nash, TJ Oligino, PD Robbins
Molecular Therapy 6 (5), 591-600, 2002
1142002
Direct retrovirus-mediated gene transfer to the synovium of the rabbit knee: implications for arthritis gene therapy
SC Ghivizzani, ER Lechman, C Tio, KM Mule, S Chada, JE McCormack, ...
Gene Therapy 4 (9), 977-982, 1997
1131997
Identification of a synovial fibroblast-specific protein transduction domain for delivery of apoptotic agents to hyperplastic synovium
Z Mi, X Lu, JC Mai, BG Ng, G Wang, ER Lechman, SC Watkins, ...
Molecular Therapy 8 (2), 295-305, 2003
942003
Reduced lymphoid lineage priming promotes human hematopoietic stem cell expansion
P van Galen, A Kreso, E Wienholds, E Laurenti, K Eppert, ER Lechman, ...
Cell stem cell 14 (1), 94-106, 2014
932014
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Artikler 1–20