| If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells IB Roninson, EV Broude, BD Chang Drug Resistance Updates 4 (5), 303-313, 2001 | 964 | 2001 |
| A senescence-like phenotype distinguishes tumor cells that undergo terminal proliferation arrest after exposure to anticancer agents BD Chang, EV Broude, M Dokmanovic, H Zhu, A Ruth, Y Xuan, ... Cancer research 59 (15), 3761-3767, 1999 | 732 | 1999 |
| Effects of p21Waf1/Cip1/Sdi1 on cellular gene expression: Implications for carcinogenesis, senescence, and age-related diseases BD Chang, K Watanabe, EV Broude, J Fang, JC Poole, TV Kalinichenko, ... Proceedings of the National Academy of Sciences 97 (8), 4291-4296, 2000 | 581 | 2000 |
| Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs BD Chang, Y Xuan, EV Broude, H Zhu, B Schott, J Fang, IB Roninson Oncogene 18 (34), 4808-4818, 1999 | 481 | 1999 |
| Molecular determinants of terminal growth arrest induced in tumor cells by a chemotherapeutic agent BD Chang, ME Swift, M Shen, J Fang, EV Broude, IB Roninson Proceedings of the National Academy of Sciences 99 (1), 389-394, 2002 | 424 | 2002 |
| Structural insight into substrate and inhibitor discrimination by human P-glycoprotein A Alam, J Kowal, E Broude, I Roninson, KP Locher Science 363 (6428), 753-756, 2019 | 366 | 2019 |
| p21Waf1/Cip1/Sdi1-induced growth arrest is associated with depletion of mitosis-control proteins and leads to abnormal mitosis and endoreduplication in recovering cells BD Chang, EV Broude, J Fang, TV Kalinichenko, R Abdryashitov, ... Oncogene 19 (17), 2165-2170, 2000 | 218 | 2000 |
| Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities DC Porter, E Farmaki, S Altilia, GP Schools, DK West, M Chen, BD Chang, ... Proceedings of the National Academy of Sciences 109 (34), 13799-13804, 2012 | 211 | 2012 |
| Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1 A Alam, R Küng, J Kowal, RA McLeod, N Tremp, EV Broude, IB Roninson, ... Proceedings of the National Academy of Sciences 115 (9), E1973-E1982, 2018 | 170 | 2018 |
| Inhibition of CDK8 mediator kinase suppresses estrogen dependent transcription and the growth of estrogen receptor positive breast cancer MSJ McDermott, AA Chumanevich, C Lim, J Liang, M Chen, S Altilia, ... Oncotarget 8 (8), 12558, 2017 | 126 | 2017 |
| Mechanism of G1-like arrest by low concentrations of paclitaxel: next cell cycle p53-dependent arrest with sub G1 DNA content mediated by prolonged mitosis ZN Demidenko, S Kalurupalle, C Hanko, CU Lim, E Broude, ... Oncogene 27 (32), 4402-4410, 2008 | 121 | 2008 |
| CDK8/19 Mediator kinases potentiate induction of transcription by NFκB M Chen, J Liang, H Ji, Z Yang, S Altilia, B Hu, A Schronce, ... Proceedings of the National Academy of Sciences 114 (38), 10208-10213, 2017 | 120 | 2017 |
| p21Waf1/Cip1/Sdi1 mediates retinoblastoma protein degradation EV Broude, ME Swift, C Vivo, BD Chang, BM Davis, S Kalurupalle, ... Oncogene 26 (48), 6954-6958, 2007 | 105 | 2007 |
| Expression of CDK8 and CDK8-interacting genes as potential biomarkers in breast cancer E V Broude, B Gyorffy, A A Chumanevich, M Chen, M SJ McDermott, ... Current cancer drug targets 15 (8), 739-749, 2015 | 97 | 2015 |
| Pharmacological induction of Hsp70 protects apoptosis-prone cells from doxorubicin: comparison with caspase-inhibitor-and cycle-arrest-mediated cytoprotection ZN Demidenko, C Vivo, HD Halicka, CJ Li, K Bhalla, EV Broude, ... Cell Death & Differentiation 13 (9), 1434-1441, 2006 | 92 | 2006 |
| CDK8 selectively promotes the growth of colon cancer metastases in the liver by regulating gene expression of TIMP3 and matrix metalloproteinases J Liang, M Chen, D Hughes, AA Chumanevich, S Altilia, V Kaza, CU Lim, ... Cancer research 78 (23), 6594-6606, 2018 | 84 | 2018 |
| Tumor-specific silencing of COPZ2 gene encoding coatomer protein complex subunit ζ2 renders tumor cells dependent on its paralogous gene COPZ1 M Shtutman, M Baig, E Levina, G Hurteau, C Lim, E Broude, M Nikiforov, ... Proceedings of the National Academy of Sciences 108 (30), 12449-12454, 2011 | 80 | 2011 |
| p21 (CDKN1A) is a negative regulator of p53 stability EV Broude, ZN Demidenko, C Vivo, ME Swift, BM Davis, ... Cell Cycle 6 (12), 1467-1470, 2007 | 78 | 2007 |
| Cellular model of p21-induced senescence M Shtutman, BD Chang, GP Schools, EV Broude Oncogene-Induced Senescence: Methods and Protocols, 31-39, 2017 | 59 | 2017 |
| Mediator kinase CDK8/CDK19 drives YAP1-dependent BMP4-induced EMT in cancer A Serrao, LM Jenkins, AA Chumanevich, B Horst, J Liang, ML Gatza, ... Oncogene 37 (35), 4792-4808, 2018 | 57 | 2018 |
