R. John MacLeod
R. John MacLeod
Associate Professor, Queen's University
Verified email at queensu.ca
TitleCited byYear
Extracellular calcium sensing and extracellular calcium signaling
EM Brown, RJ MacLeod
Physiological reviews 81 (1), 239-297, 2001
13782001
Regulation of MAP kinase by calcium-sensing receptor in bovine parathyroid and CaR-transfected HEK293 cells
O Kifor, RJ MacLeod, R Diaz, M Bai, T Yamaguchi, T Yao, I Kifor, ...
American Journal of Physiology-Renal Physiology 280 (2), F291-F302, 2001
2842001
Filamin-A binds to the carboxyl-terminal tail of the calcium-sensing receptor, an interaction that participates in CaR-mediated activation of mitogen-activated protein kinase
G Hjälm, RJ MacLeod, O Kifor, N Chattopadhyay, EM Brown
Journal of Biological Chemistry 276 (37), 34880-34887, 2001
1932001
Wnt5a secretion stimulated by the extracellular calcium-sensing receptor inhibits defective Wnt signaling in colon cancer cells
RJ MacLeod, M Hayes, I Pacheco
American Journal of Physiology-Gastrointestinal and Liver Physiology 293 (1 …, 2007
1522007
Stimulation of human neutrophils by 5-oxo-6, 8, 11, 14-eicosatetraenoic acid by a mechanism independent of the leukotriene B4 receptor.
WS Powell, S Gravel, RJ MacLeod, E Mills, M Hashefi
Journal of Biological Chemistry 268 (13), 9280-9286, 1993
1351993
Calcium-sensing receptor stimulates PTHrP release by pathways dependent on PKC, p38 MAPK, JNK, and ERK1/2 in H-500 cells
J Tfelt-Hansen, RJ MacLeod, N Chattopadhyay, S Yano, S Quinn, X Ren, ...
American Journal of Physiology-Endocrinology and Metabolism 285 (2), E329-E337, 2003
1242003
Calcium-sensing receptor activation stimulates parathyroid hormone-related protein secretion in prostate cancer cells: role of epidermal growth factor receptor transactivation
S Yano, RJ Macleod, N Chattopadhyay, J Tfelt-Hansen, O Kifor, ...
Bone 35 (3), 664-672, 2004
1132004
Cl-secretion in a model intestinal epithelium induced by a neutrophil-derived secretagogue.
JL Madara, C Parkos, S Colgan, RJ MacLeod, S Nash, J Matthews, ...
The Journal of clinical investigation 89 (6), 1938-1944, 1992
1001992
FGF9-induced proliferative response to eosinophilic inflammation in oesophagitis
DJ Mulder, I Pacheco, DJ Hurlbut, N Mak, GT Furuta, RJ MacLeod, ...
Gut 58 (2), 166-173, 2009
772009
PTHrP stimulated by the calcium-sensing receptor requires MAP kinase activation
RJ MacLeod, N Chattopadhyay, EM Brown
American Journal of Physiology-Endocrinology and Metabolism 284 (2), E435-E442, 2003
752003
Metabolism and biologic effects of 5-oxoeicosanoids on human neutrophils.
WS Powell, RJ MacLeod, S Gravel, F Gravelle, A Bhakar
The Journal of Immunology 156 (1), 336-342, 1996
611996
CaSR stimulates secretion of Wnt5a from colonic myofibroblasts to stimulate CDX2 and sucrase-isomaltase using Ror2 on intestinal epithelia
II Pacheco, RJ MacLeod
American Journal of Physiology-Gastrointestinal and Liver Physiology 295 (4 …, 2008
592008
Corticostatic peptides cause nifedipine-sensitive volume reduction in jejunal villus enterocytes
RJ MacLeod, JR Hamilton, A Bateman, D Belcourt, J Hu, HP Bennett, ...
Proceedings of the National Academy of Sciences 88 (2), 552-556, 1991
591991
The isolation and characterization of a novel corticostatin/defensin-like peptide from the kidney
A Bateman, RJ MacLeod, P Lembessis, J Hu, F Esch, S Solomon
Journal of Biological Chemistry 271 (18), 10654-10659, 1996
581996
The extracellular calcium-sensing receptor reciprocally regulates the secretion of BMP-2 and the BMP antagonist Noggin in colonic myofibroblasts
D Peiris, I Pacheco, C Spencer, RJ MacLeod
American Journal of Physiology-Gastrointestinal and Liver Physiology 292 (3 …, 2007
562007
Characterization of the inhibitory effect of boiled rice on intestinal chloride secretion in guinea pig crypt cells
CJ Mathews, RJ MacLeod, SX Zheng, JW Hanrahan, HPJ Bennett, ...
Gastroenterology 116 (6), 1342-1347, 1999
551999
Volume regulation initiated by Na (+)-nutrient cotransport in isolated mammalian villus enterocytes
RJ MAcLEOD, JR Hamilton
American Journal of Physiology-Gastrointestinal and Liver Physiology 260 (1 …, 1991
531991
Extracellular calcium-sensing receptor transactivates the epidermal growth factor receptor by a triple-membrane-spanning signaling mechanism
RJ MacLeod, S Yano, N Chattopadhyay, EM Brown
Biochemical and biophysical research communications 320 (2), 455-460, 2004
492004
Regulatory volume increase in mammalian jejunal villus cells is due to bumetanide-sensitive NaKCl2 cotransport
RJ MAcLEOD, JR Hamilton
American Journal of Physiology-Gastrointestinal and Liver Physiology 258 (5 …, 1990
491990
Physiological significance of L-amino acid sensing by extracellular Ca2+-sensing receptors
AD Conigrave, HC Mun, SC Brennan, AD Conigrave, SJ Quinn, ...
Biochemical Society Transactions 35 (5), 1195-1198, 2007
482007
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