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Jonathan H Chen
Jonathan H Chen
Massachusetts General Hospital
Verified email at mgh.harvard.edu
Title
Cited by
Cited by
Year
Defining T cell states associated with response to checkpoint immunotherapy in melanoma
M Sade-Feldman, K Yizhak, SL Bjorgaard, JP Ray, CG de Boer, ...
Cell 175 (4), 998-1013. e20, 2018
13412018
Resistance to checkpoint blockade therapy through inactivation of antigen presentation
M Sade-Feldman, YJ Jiao, JH Chen, MS Rooney, M Barzily-Rokni, ...
Nature communications 8 (1), 1-11, 2017
7982017
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets
TM Delorey, CGK Ziegler, G Heimberg, R Normand, Y Yang, ...
Nature 595 (7865), 107-113, 2021
5862021
Lineage tracing in humans enabled by mitochondrial mutations and single-cell genomics
LS Ludwig, CA Lareau, JC Ulirsch, E Christian, C Muus, LH Li, K Pelka, ...
Cell 176 (6), 1325-1339. e22, 2019
3882019
The transcription factor FoxO1 sustains expression of the inhibitory receptor PD-1 and survival of antiviral CD8+ T cells during chronic infection
MM Staron, SM Gray, HD Marshall, IA Parish, JH Chen, CJ Perry, G Cui, ...
Immunity 41 (5), 802-814, 2014
3632014
Spatially organized multicellular immune hubs in human colorectal cancer
K Pelka, M Hofree, JH Chen, S Sarkizova, JD Pirl, V Jorgji, A Bejnood, ...
Cell 184 (18), 4734-4752. e20, 2021
2852021
Costimulatory molecule-targeted antibody therapy of a spontaneous autoimmune disease
Y Sun, HM Chen, SK Subudhi, J Chen, R Koka, L Chen, YX Fu
Nature medicine 8 (12), 1405-1413, 2002
2432002
Temporal and spatial heterogeneity of host response to SARS-CoV-2 pulmonary infection
N Desai, A Neyaz, A Szabolcs, AR Shih, JH Chen, V Thapar, LT Nieman, ...
Nature communications 11 (1), 1-15, 2020
2212020
Histopathologic features of colitis due to immunotherapy with anti-PD-1 antibodies
JH Chen, MK Pezhouh, GY Lauwers, R Masia
The American journal of surgical pathology 41 (5), 643-654, 2017
1652017
Prostaglandin E2 and programmed cell death 1 signaling coordinately impair CTL function and survival during chronic viral infection
JH Chen, CJ Perry, YC Tsui, MM Staron, IA Parish, CX Dominguez, ...
Nature medicine 21 (4), 327-334, 2015
1512015
Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps
B Chen, S Cherie’R, ET McKinley, AJ Simmons, MA Ramirez-Solano, ...
Cell 184 (26), 6262-6280. e26, 2021
1392021
Large-scale topological changes restrain malignant progression in colorectal cancer
SE Johnstone, A Reyes, Y Qi, C Adriaens, E Hegazi, K Pelka, JH Chen, ...
Cell 182 (6), 1474-1489. e23, 2020
1362020
Increased numbers of preexisting memory CD8 T cells and decreased T-bet expression can restrain terminal differentiation of secondary effector and memory CD8 T cells
NS Joshi, W Cui, CX Dominguez, JH Chen, TW Hand, SM Kaech
The Journal of Immunology 187 (8), 4068-4076, 2011
1252011
Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment
WL Hwang, KA Jagadeesh, JA Guo, HI Hoffman, P Yadollahpour, ...
Nature Genetics, 1-14, 2022
1222022
Chronic viral infection promotes sustained Th1-derived immunoregulatory IL-10 via BLIMP-1
IA Parish, HD Marshall, MM Staron, PA Lang, A Brüstle, JH Chen, W Cui, ...
The Journal of clinical investigation 124 (8), 3455-3468, 2014
1082014
Immune‐related adverse events in the gastrointestinal tract: diagnostic utility of upper gastrointestinal biopsies
ML Zhang, A Neyaz, D Patil, J Chen, M Dougan, V Deshpande
Histopathology 76 (2), 233-243, 2020
742020
Viperin is highly induced in neutrophils and macrophages during acute and chronic lymphocytic choriomeningitis virus infection
ER Hinson, NS Joshi, JH Chen, C Rahner, YW Jung, X Wang, SM Kaech, ...
The Journal of Immunology 184 (10), 5723-5731, 2010
672010
SO-26 Clinical efficacy of combined BRAF, MEK, and PD-1 inhibition in BRAFV600E colorectal cancer patients
R Corcoran, M Giannakis, J Allen, J Chen, K Pelka, S Chao, J Meyerhardt, ...
Annals of Oncology 31, S226-S227, 2020
482020
Immunotherapy with agonistic anti-CD137: two sides of a coin
Y Sun, JH Chen, Y Fu
Cell Mol Immunol 1 (1), 31-36, 2004
452004
Regulation of follicular dendritic cell networks by activated T cells: the role of CD137 signaling
Y Sun, SE Blink, JH Chen, YX Fu
The Journal of Immunology 175 (2), 884-890, 2005
392005
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Articles 1–20