Calmodulin controls the rod photoreceptor CNG channel through an unconventional binding site in the N‐terminus of the β‐subunit D Weitz, M Zoche, F Müller, M Beyermann, HG Körschen, UB Kaupp, ... The EMBO Journal, 1998 | 132 | 1998 |
Harmonization and standardization of panel-based tumor mutational burden measurement: real-world results and recommendations of the quality in pathology study A Stenzinger, V Endris, J Budczies, S Merkelbach-Bruse, D Kazdal, ... Journal of Thoracic Oncology 15 (7), 1177-1189, 2020 | 99 | 2020 |
The Tumor Profiler Study: integrated, multi-omic, functional tumor profiling for clinical decision support A Irmisch, X Bonilla, S Chevrier, KV Lehmann, F Singer, NC Toussaint, ... Cancer Cell 39 (3), 288-293, 2021 | 89 | 2021 |
Distinct molecular recognition of calmodulin-binding sites in the neuronal and macrophage nitric oxide synthases: a surface plasmon resonance study M Zoche, M Bienert, M Beyermann, KW Koch Biochemistry 35 (26), 8742-8747, 1996 | 56 | 1996 |
STRN-ALK rearranged malignant peritoneal mesothelioma with dramatic response following ceritinib treatment JH Rüschoff, E Gradhand, A Kahraman, H Rees, JL Ferguson, ... JCO precision oncology 3, 2019 | 48 | 2019 |
Trithiocarbonates—Exploration of a new head group for HDAC inhibitors F Dehmel, T Ciossek, T Maier, S Weinbrenner, B Schmidt, M Zoche, ... Bioorganic & medicinal chemistry letters 17 (17), 4746-4752, 2007 | 46 | 2007 |
Ligand sensitivity of the α2 subunit from the bovine cone cGMP-gated channel is modulated by protein kinase C but not by calmodulin F Müller, M Vantler, D Weitz, E Eismann, M Zoche, KW Koch, UB Kaupp The Journal of Physiology 532 (Pt 2), 399, 2001 | 40 | 2001 |
Genomic landscape of pleural and peritoneal mesothelioma tumours S Hiltbrunner, Z Fleischmann, ES Sokol, M Zoche, E Felley-Bosco, ... British Journal of Cancer 127 (11), 1997-2005, 2022 | 37 | 2022 |
Clonal hematopoiesis in hospitalized elderly patients with COVID-19 E Hameister, SM Stolz, Y Fuhrer, F Thienemann, DJ Schaer, J Nemeth, ... Hemasphere 4 (4), e453, 2020 | 24 | 2020 |
Purified retinal nitric oxide synthase enhances ADP‐ribosylation of rod outer segment proteins M Zoche, KW Koch FEBS letters 357 (2), 178-182, 1995 | 23 | 1995 |
Introduction of a Phosphate at Serine741 of the Calmodulin-Binding Domain of the Neuronal Nitric Oxide Synthase (NOS-I) Prevents Binding of Calmodulin M Zoche, M Beyermann, KW Koch Walter de Gruyter, Berlin/New York 378 (8), 851-858, 1997 | 20 | 1997 |
Benzofuran derivatives C Schmeck, U Müller, G Schmidt, J Pernerstorfer, H Bischoff, ... US Patent 7,015,246, 2006 | 12 | 2006 |
Clinicopathological and genomic profiles of atypical fibroxanthoma and pleomorphic dermal sarcoma identify overlapping signatures with a high mutational burden M Ak, A Kahraman, FM Arnold, P Turko, MP Levesque, M Zoche, ... Genes 12 (7), 974, 2021 | 11 | 2021 |
Comparison of calling pipelines for whole genome sequencing: an empirical study demonstrating the importance of mapping and alignment RO Betschart, A Thiéry, D Aguilera-Garcia, M Zoche, H Moch, ... Scientific Reports 12 (1), 21502, 2022 | 10 | 2022 |
Targeting Secondary and Tertiary Resistance to BRAF Inhibition in BRAF V600E-Mutated Metastatic Colorectal Cancer. D Akhoundova Sanoyan, H Pietge, S Hussung, M Kiessling, C Britschgi, ... JCO precision oncology 5, 1082-1087, 2021 | 10 | 2021 |
Acquired resistance to anti-PD1 therapy in patients with NSCLC associates with immunosuppressive T cell phenotype S Hiltbrunner, L Cords, S Kasser, SN Freiberger, S Kreutzer, ... Nature Communications 14 (1), 5154, 2023 | 7 | 2023 |
ROS1 genomic rearrangements are rare actionable drivers in microsatellite stable colorectal cancer D Akhoundova, S Hussung, S Sivakumar, A Töpfer, M Rechsteiner, ... International journal of cancer 151 (12), 2161-2171, 2022 | 7 | 2022 |
Molecular and immunophenotypic characterization of SMARCB1 (INI1)-deficient intrathoracic Neoplasms M Haberecker, MM Bühler, AP Mendieta, R Guggenberger, F Arnold, ... Modern Pathology 35 (12), 1860-1869, 2022 | 7 | 2022 |
Unravelling homologous recombination repair deficiency and therapeutic opportunities in soft tissue and bone sarcoma L Planas‐Paz, A Pliego‐Mendieta, C Hagedorn, D Aguilera‐Garcia, ... EMBO molecular medicine 15 (4), e16863, 2023 | 4 | 2023 |
Prognostic impact of tumour mutational burden in resected stage I and II lung adenocarcinomas from a European Thoracic Oncology Platform Lungscape cohort L Bubendorf, M Zoche, U Dafni, JH Rüschoff, SS Prince, N Marti, ... Lung Cancer 174, 27-35, 2022 | 4 | 2022 |