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Patrick M. Dougherty
Patrick M. Dougherty
Professor, The University of Texas M.D. Anderson Cancer Center
Verificeret mail på mdanderson.org
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The cancer chemotherapeutic paclitaxel increases human and rodent sensory neuron responses to TRPV1 by activation of TLR4
Y Li, P Adamek, H Zhang, CE Tatsui, LD Rhines, P Mrozkova, Q Li, ...
Journal of Neuroscience 35 (39), 13487-13500, 2015
2252015
Mechanisms involved in the development of chemotherapy-induced neuropathy
JA Boyette-Davis, ET Walters, PM Dougherty
Pain management 5 (4), 285-296, 2015
1752015
Enhanced excitability of primary sensory neurons and altered gene expression of neuronal ion channels in dorsal root ganglion in paclitaxel-induced peripheral neuropathy
H Zhang, PM Dougherty
Anesthesiology 120 (6), 1463-1475, 2014
1592014
Astrocytes, but not microglia, are activated in oxaliplatin and bortezomib-induced peripheral neuropathy in the rat
CR Robinson, H Zhang, PM Dougherty
Neuroscience 274, 308-317, 2014
1422014
A p38 mitogen-activated protein kinase-dependent mechanism of disinhibition in spinal synaptic transmission induced by tumor necrosis factor-α
H Zhang, H Nei, PM Dougherty
Journal of Neuroscience 30 (38), 12844-12855, 2010
1332010
MAPK signaling downstream to TLR4 contributes to paclitaxel-induced peripheral neuropathy
Y Li, H Zhang, AK Kosturakis, RM Cassidy, H Zhang, ...
Brain, behavior, and immunity 49, 255-266, 2015
1262015
Basic science and clinical management of painful and non-painful chemotherapy-related neuropathy
JH Kim, PM Dougherty, S Abdi
Gynecologic oncology 136 (3), 453-459, 2015
972015
Subclinical peripheral neuropathy is a common finding in colorectal cancer patients prior to chemotherapy
JA Boyette-Davis, C Eng, XS Wang, CS Cleeland, ...
Clinical Cancer Research 18 (11), 3180-3187, 2012
712012
A quantitative sensory analysis of peripheral neuropathy in colorectal cancer and its exacerbation by oxaliplatin chemotherapy
M de Carvalho Barbosa, AK Kosturakis, C Eng, G Wendelschafer-Crabb, ...
Cancer research 74 (21), 5955-5962, 2014
702014
Dynamic effects of TNF-α on synaptic transmission in mice over time following sciatic nerve chronic constriction injury
H Zhang, H Zhang, PM Dougherty
Journal of neurophysiology 110 (7), 1663-1671, 2013
472013
Subclinical peripheral neuropathy in patients with multiple myeloma before chemotherapy is correlated with decreased fingertip innervation density
AK Kosturakis, Z He, Y Li, JA Boyette-Davis, N Shah, SK Thomas, ...
Journal of Clinical Oncology 32 (28), 3156, 2014
452014
Spinal astrocyte gap junction and glutamate transporter expression contributes to a rat model of bortezomib-induced peripheral neuropathy
CR Robinson, PM Dougherty
Neuroscience 285, 1-10, 2015
442015
Acute inhibition of signalling phenotype of spinal GABAergic neurons by tumour necrosis factor‐α
H Zhang, PM Dougherty
The Journal of physiology 589 (18), 4511-4526, 2011
342011
Measuring therapy-induced peripheral neuropathy: preliminary development and validation of the treatment-induced neuropathy assessment scale
TR Mendoza, XS Wang, LA Williams, Q Shi, EG Vichaya, PM Dougherty, ...
The Journal of Pain 16 (10), 1032-1043, 2015
312015
Anatomy and physiology of somatosensory and pain processing
SN Raja, PM Dougherty
Essentials of pain medicine, 1-6, 2004
282004
Peripheral neuropathic pain: signs, symptoms, mechanisms, and causes: are they linked?
LA Colvin, PM Dougherty
British Journal of Anaesthesia 114 (3), 361-363, 2015
232015
Altered discharges of spinal neurons parallel the behavioral phenotype shown by rats with bortezomib related chemotherapy induced peripheral neuropathy
CR Robinson, H Zhang, PM Dougherty
Brain research 1574, 6-13, 2014
232014
Response properties of dorsal root reflexes in cutaneous C fibers before and after intradermal capsaicin injection in rats
HR Weng, PM Dougherty
Neuroscience 132 (3), 823-831, 2005
232005
Distribution of cardiovascular related cells within the human thalamus
SM Oppenheimer, N Kulshreshtha, FA Lenz, Z Zhang, LH Rowland, ...
Clinical Autonomic Research 8, 173-179, 1998
231998
Subclinical pretreatment sensory deficits appear to predict the development of pain and numbness in patients with multiple myeloma undergoing chemotherapy
EG Vichaya, XS Wang, JA Boyette-Davis, TR Mendoza, Z He, SK Thomas, ...
Cancer chemotherapy and pharmacology 71, 1531-1540, 2013
222013
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Artikler 1–20