| A comparative encyclopedia of DNA elements in the mouse genome F Yue, Y Cheng, A Breschi, J Vierstra, W Wu, T Ryba, R Sandstrom, Z Ma, ... Nature 515 (7527), 355-364, 2014 | 2028 | 2014 |
| Design of a synthetic yeast genome SM Richardson, LA Mitchell, G Stracquadanio, K Yang, JS Dymond, ... Science 355 (6329), 1040-1044, 2017 | 633 | 2017 |
| Enhanced regulatory sequence prediction using gapped k-mer features M Ghandi, D Lee, M Mohammad-Noori, MA Beer PLoS computational biology 10 (7), e1003711, 2014 | 556 | 2014 |
| A method to predict the impact of regulatory variants from DNA sequence D Lee, DU Gorkin, M Baker, BJ Strober, AL Asoni, AS McCallion, MA Beer Nature genetics 47 (8), 955-961, 2015 | 501 | 2015 |
| Discriminative prediction of mammalian enhancers from DNA sequence D Lee, R Karchin, MA Beer Genome Research, 2011 | 292 | 2011 |
| gkmSVM: an R package for gapped-kmer SVM M Ghandi, M Mohammad-Noori, N Ghareghani, D Lee, L Garraway, ... Bioinformatics 32 (14), 2205-2207, 2016 | 176 | 2016 |
| kmer-SVM: a web server for identifying predictive regulatory sequence features in genomic data sets C Fletez-Brant, D Lee, AS McCallion, MA Beer Nucleic acids research 41 (W1), W544-W556, 2013 | 147 | 2013 |
| LS-GKM: a new gkm-SVM for large-scale datasets D Lee Bioinformatics 32 (14), 2196-2198, 2016 | 139 | 2016 |
| Enhancer Variants Synergistically Drive Dysfunction of a Gene Regulatory Network In Hirschsprung Disease S Chatterjee, A Kapoor, JA Akiyama, DR Auer, D Lee, S Gabriel, ... Cell 167 (2), 355-368. e10, 2016 | 134 | 2016 |
| Divergent functions of hematopoietic transcription factors in lineage priming and differentiation during erythro-megakaryopoiesis M Pimkin, AV Kossenkov, T Mishra, CS Morrissey, W Wu, CA Keller, ... Genome research 24 (12), 1932-1944, 2014 | 118 | 2014 |
| Integration of ChIP-seq and machine learning reveals enhancers and a predictive regulatory sequence vocabulary in melanocytes DU Gorkin, D Lee, X Reed, C Fletez-Brant, SL Bessling, SK Loftus, ... Genome Research, 2012 | 83 | 2012 |
| Common risk variants in NPHS1 and TNFSF15 are associated with childhood steroid-sensitive nephrotic syndrome X Jia, T Yamamura, R Gbadegesin, MT McNulty, K Song, Y Hitomi, D Lee, ... Kidney international 98 (5), 1308-1322, 2020 | 54 | 2020 |
| Multiple SCN5A variant enhancers modulate its cardiac gene expression and the QT interval A Kapoor, D Lee, L Zhu, EZ Soliman, ML Grove, E Boerwinkle, DE Arking, ... Proceedings of the National Academy of Sciences 116 (22), 10636-10645, 2019 | 30 | 2019 |
| Human cardiac cis-regulatory elements, their cognate transcription factors, and regulatory DNA sequence variants D Lee, A Kapoor, A Safi, L Song, MK Halushka, GE Crawford, ... Genome research 28 (10), 1577-1588, 2018 | 27 | 2018 |
| Multi-population genome-wide association study implicates immune and non-immune factors in pediatric steroid-sensitive nephrotic syndrome A Barry, MT McNulty, X Jia, Y Gupta, H Debiec, Y Luo, C Nagano, ... Nature communications 14 (1), 2481, 2023 | 26 | 2023 |
| Rare coding variants associated with blood pressure variation in 15 914 individuals of African ancestry P Nandakumar, D Lee, MA Richard, F Tekola-Ayele, BO Tayo, E Ware, ... Journal of hypertension 35 (7), 1381-1389, 2017 | 25 | 2017 |
| Mapping genomic regulation of kidney disease and traits through high-resolution and interpretable eQTLs SK Han, MT McNulty, CJ Benway, P Wen, A Greenberg, ... Nature Communications 14 (1), 2229, 2023 | 19 | 2023 |
| Methods, Systems and Devices Comprising Support Vector Machine for Regulatory Sequence Features M Beer, D Lee US Patent App. 14/013,920, 2014 | 18 | 2014 |
| Cardiomyocytes have mosaic patterns of protein expression TY Wang, D Lee, K Fox-Talbot, DE Arking, A Chakravarti, MK Halushka Cardiovascular Pathology 34, 50-57, 2018 | 16 | 2018 |
| Quality assessment and refinement of chromatin accessibility data using a sequence-based predictive model SK Han, Y Muto, PC Wilson, BD Humphreys, MG Sampson, A Chakravarti, ... Proceedings of the National Academy of Sciences 119 (51), e2212810119, 2022 | 9 | 2022 |
Michael A BeerDepts. of Biomedical Engineering, Genetic Medicine, and Oncology, Johns HopkinsVerificeret mail på jhu.edu
