| International multisite study of human-induced pluripotent stem cell-derived cardiomyocytes for drug proarrhythmic potential assessment K Blinova, Q Dang, D Millard, G Smith, J Pierson, L Guo, M Brock, HR Lu, ... Cell reports 24 (13), 3582-3592, 2018 | 286 | 2018 |
| Comprehensive translational assessment of human-induced pluripotent stem cell derived cardiomyocytes for evaluating drug-induced arrhythmias K Blinova, J Stohlman, J Vicente, D Chan, L Johannesen, ... Toxicological Sciences 155 (1), 234-247, 2017 | 243 | 2017 |
| Distribution of mitochondrial NADH fluorescence lifetimes: steady-state kinetics of matrix NADH interactions K Blinova, S Carroll, S Bose, AV Smirnov, JJ Harvey, JR Knutson, ... Biochemistry 44 (7), 2585-2594, 2005 | 196 | 2005 |
| Late sodium current block for drug‐induced long QT syndrome: results from a prospective clinical trial L Johannesen, J Vicente, JW Mason, C Erato, C Sanabria, K Waite‐Labott, ... Clinical Pharmacology & Therapeutics 99 (2), 214-223, 2016 | 134 | 2016 |
| Common genetic variant risk score is associated with drug-induced QT prolongation and torsade de pointes risk: a pilot study DG Strauss, J Vicente, L Johannesen, K Blinova, JW Mason, P Weeke, ... Circulation 135 (14), 1300-1310, 2017 | 116 | 2017 |
| Mitochondrial NADH fluorescence is enhanced by complex I binding K Blinova, RL Levine, ES Boja, GL Griffiths, ZD Shi, B Ruddy, RS Balaban Biochemistry 47 (36), 9636-9645, 2008 | 107 | 2008 |
| Comprehensive in vitro proarrhythmia assay (CiPA) update from a cardiac safety research consortium/health and environmental sciences institute/FDA meeting DG Strauss, G Gintant, Z Li, W Wu, K Blinova, J Vicente, JR Turner, ... Therapeutic Innovation & Regulatory Science 53 (4), 519-525, 2019 | 82 | 2019 |
| Use of human MonoMac6 cells for development of in vitro assay predictive of adjuvant safety in vivo M Zaitseva, T Romantseva, K Blinova, J Beren, L Sirota, D Drane, ... Vaccine 30 (32), 4859-4865, 2012 | 59 | 2012 |
| 32P labeling of protein phosphorylation and metabolite association in the mitochondria matrix AM Aponte, D Phillips, RA Harris, K Blinova, S French, DT Johnson, ... Methods in enzymology 457, 63-80, 2009 | 51 | 2009 |
| Use of 32P To Study Dynamics of the Mitochondrial Phosphoproteome AM Aponte, D Phillips, RK Hopper, DT Johnson, RA Harris, K Blinova, ... Journal of proteome research 8 (6), 2679-2695, 2009 | 50 | 2009 |
| Clinical trials in a dish DG Strauss, K Blinova Trends in pharmacological sciences 38 (1), 4-7, 2017 | 46 | 2017 |
| Clinical Trial in a Dish: Personalized Stem Cell–Derived Cardiomyocyte Assay Compared With Clinical Trial Results for Two QT‐Prolonging Drugs K Blinova, D Schocken, D Patel, C Daluwatte, J Vicente, JC Wu, ... Clinical and translational science 12 (6), 687-697, 2019 | 41 | 2019 |
| Differences in PGE2 Production between Primary Human Monocytes and Differentiated Macrophages: Role of IL-1β and TRIF/IRF3 Y Endo, K Blinova, T Romantseva, H Golding, M Zaitseva PloS one 9 (5), e98517, 2014 | 35 | 2014 |
| Repolarization studies using human stem cell-derived cardiomyocytes: Validation studies and best practice recommendations G Gintant, EP Kaushik, T Feaster, S Stoelzle-Feix, Y Kanda, T Osada, ... Regulatory toxicology and pharmacology 117, 104756, 2020 | 34 | 2020 |
| Assessment of proarrhythmic potential of drugs in optogenetically paced induced pluripotent stem cell-derived cardiomyocytes D Patel, J Stohlman, Q Dang, DG Strauss, K Blinova Toxicological sciences 170 (1), 167-179, 2019 | 28 | 2019 |
| Fluctuation analysis of mitochondrial NADH fluorescence signals in confocal and two‐photon microscopy images of living cardiac myocytes K Blinova, C Combs, P Kellman, RS Balaban Journal of microscopy 213 (1), 70-75, 2004 | 28 | 2004 |
| Comparative analysis of media effects on human induced pluripotent stem cell-derived cardiomyocytes in proarrhythmia risk assessment D Schocken, J Stohlman, J Vicente, D Chan, D Patel, MK Matta, V Patel, ... Journal of pharmacological and toxicological methods 90, 39-47, 2018 | 27 | 2018 |
| Mechanisms of QT prolongation by buprenorphine cannot be explained by direct hERG channel block PN Tran, J Sheng, AL Randolph, CA Baron, N Thiebaud, M Ren, M Wu, ... PLoS One 15 (11), e0241362, 2020 | 21 | 2020 |
| Chronic cardiotoxicity assays using human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) A Narkar, JM Willard, K Blinova International Journal of Molecular Sciences 23 (6), 3199, 2022 | 16 | 2022 |
| Acute effects of cardiac contractility modulation on human induced pluripotent stem cell–derived cardiomyocytes TK Feaster, M Casciola, A Narkar, K Blinova Physiological reports 9 (21), e15085, 2021 | 14 | 2021 |
David G StraussFDAVerificeret mail på fda.hhs.gov
