| Deep learning automates the quantitative analysis of individual cells in live-cell imaging experiments DA Van Valen, T Kudo, KM Lane, DN Macklin, NT Quach, MM DeFelice, ... PLoS computational biology 12 (11), e1005177, 2016 | 563 | 2016 |
| Dicer1 functions as a haploinsufficient tumor suppressor MS Kumar, RE Pester, CY Chen, K Lane, C Chin, J Lu, DG Kirsch, ... Genes & development 23 (23), 2700-2704, 2009 | 551 | 2009 |
| Fusion of FIG to the receptor tyrosine kinase ROS in a glioblastoma with an interstitial del (6)(q21q21) A Charest, K Lane, K McMahon, J Park, E Preisinger, H Conroy, ... Genes, Chromosomes and Cancer 37 (1), 58-71, 2003 | 275 | 2003 |
| ROS fusion tyrosine kinase activates a SH2 domain–containing phosphatase-2/phosphatidylinositol 3-Kinase/mammalian target of rapamycin signaling axis to form glioblastoma in mice A Charest, EW Wilker, ME McLaughlin, K Lane, R Gowda, S Coven, ... Cancer research 66 (15), 7473-7481, 2006 | 203 | 2006 |
| Measuring signaling and RNA-seq in the same cell links gene expression to dynamic patterns of NF-κB activation K Lane, D Van Valen, MM DeFelice, DN Macklin, T Kudo, A Jaimovich, ... Cell systems 4 (4), 458-469. e5, 2017 | 161 | 2017 |
| Simultaneous cross-evaluation of heterogeneous E. coli datasets via mechanistic simulation DN Macklin, TA Ahn-Horst, H Choi, NA Ruggero, J Carrera, JC Mason, ... Science 369 (6502), eaav3751, 2020 | 128 | 2020 |
| Oncogenic targeting of an activated tyrosine kinase to the Golgi apparatus in a glioblastoma A Charest, V Kheifets, J Park, K Lane, K McMahon, CL Nutt, D Housman Proceedings of the National Academy of Sciences 100 (3), 916-921, 2003 | 119 | 2003 |
| Association of a novel PDZ domain-containing peripheral Golgi protein with the Q-SNARE (Q-solubleN-ethylmaleimide-sensitive fusion protein (NSF) attachment protein receptor … A Charest, K Lane, K McMahon, DE Housman Journal of Biological Chemistry 276 (31), 29456-29465, 2001 | 114 | 2001 |
| Impaired SHP2-mediated extracellular signal-regulated kinase activation contributes to gefitinib sensitivity of lung cancer cells with epidermal growth factor receptor … MJ Lazzara, K Lane, R Chan, PJ Jasper, MB Yaffe, PK Sorger, T Jacks, ... Cancer research 70 (9), 3843-3850, 2010 | 75 | 2010 |
| Mouse models of human non-small-cell lung cancer: raising the bar CFB Kim, EL Jackson, DG Kirsch, J Grimm, AT Shaw, K Lane, J Kissil, ... Cold Spring Harbor symposia on quantitative biology 70, 241-250, 2005 | 74 | 2005 |
| Mechanically resolved imaging of bacteria using expansion microscopy Y Lim, AL Shiver, M Khariton, KM Lane, KM Ng, SR Bray, J Qin, ... PLoS biology 17 (10), e3000268, 2019 | 54 | 2019 |
| Epigenetic regulation of c-ROS receptor tyrosine kinase expression in malignant gliomas HJ Jun, S Woolfenden, S Coven, K Lane, R Bronson, D Housman, ... Cancer research 69 (6), 2180-2184, 2009 | 53 | 2009 |
| ROS1 signaling regulates epithelial differentiation in the epididymis HJ Jun, J Roy, TB Smith, LB Wood, K Lane, S Woolfenden, D Punko, ... Endocrinology 155 (9), 3661-3673, 2014 | 35 | 2014 |
| Escalating threat levels of bacterial infection can be discriminated by distinct MAPK and NF-κB signaling dynamics in single host cells K Lane, M Andres-Terre, T Kudo, DM Monack, MW Covert Cell Systems 8 (3), 183-196. e4, 2019 | 28 | 2019 |
| Navigating environmental transitions: the role of phenotypic variation in bacterial responses MR Spratt, K Lane Mbio 13 (6), e02212-22, 2022 | 16 | 2022 |
| Combinatorial processing of bacterial and host-derived innate immune stimuli at the single-cell level MV Gutschow, JC Mason, KM Lane, I Maayan, JJ Hughey, BT Bajar, ... Molecular biology of the cell 30 (2), 282-292, 2019 | 13 | 2019 |
| Physical mapping of the mouse tilted locus identifies an association between human deafness loci DFNA6/14 and vestibular system development B Hurle, K Lane, J Kenney, LM Tarantino, M Bucan, BH Brownstein, ... Genomics 77 (3), 189-199, 2001 | 11 | 2001 |
| Measuring Signaling and RNA-Seq in the Same Cell Links Gene Expression to Dynamic Patterns of NF-κB Activation. Cell Syst. 4, 458-469. e5 K Lane, D Van Valen, MM DeFelice, DN Macklin, T Kudo, A Jaimovich, ... | 7 | 2017 |
| A multiplexed epitope barcoding strategy that enables dynamic cellular phenotypic screens T Kudo, K Lane, MW Covert Cell Systems 13 (5), 376-387. e8, 2022 | 6 | 2022 |
| Negative feedback regulation as a means to constrain the oncogenic potential of mutant Egfr in NSCLC KM Lane Massachusetts Institute of Technology, 2011 | 1 | 2011 |
