Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen J Pallesen, N Wang, KS Corbett, D Wrapp, RN Kirchdoerfer, HL Turner, ... Proceedings of the National Academy of Sciences 114 (35), E7348-E7357, 2017 | 1123 | 2017 |
Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors RN Kirchdoerfer, AB Ward Nature communications 10 (1), 2342, 2019 | 959 | 2019 |
Pre-fusion structure of a human coronavirus spike protein RN Kirchdoerfer, CA Cottrell, N Wang, J Pallesen, HM Yassine, HL Turner, ... Nature 531 (7592), 118-121, 2016 | 851 | 2016 |
Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis RN Kirchdoerfer, N Wang, J Pallesen, D Wrapp, HL Turner, CA Cottrell, ... Scientific reports 8 (1), 15701, 2018 | 536 | 2018 |
Organization of the influenza virus replication machinery A Moeller, RN Kirchdoerfer, CS Potter, B Carragher, IA Wilson Science 338 (6114), 1631-1634, 2012 | 321 | 2012 |
Nucleotide analogues as inhibitors of SARS-CoV-2 polymerase, a key drug target for COVID-19 M Chien, TK Anderson, S Jockusch, C Tao, X Li, S Kumar, JJ Russo, ... Journal of proteome research 19 (11), 4690-4697, 2020 | 294 | 2020 |
Assembly of the Ebola virus nucleoprotein from a chaperoned VP35 complex RN Kirchdoerfer, DM Abelson, S Li, MR Wood, EO Saphire Cell reports 12 (1), 140-149, 2015 | 145* | 2015 |
A library of nucleotide analogues terminate RNA synthesis catalyzed by polymerases of coronaviruses that cause SARS and COVID-19 S Jockusch, C Tao, X Li, TK Anderson, M Chien, S Kumar, JJ Russo, ... Antiviral research 180, 104857, 2020 | 137 | 2020 |
Nucleotide analogues as inhibitors of SARS‐CoV polymerase J Ju, X Li, S Kumar, S Jockusch, M Chien, C Tao, I Morozova, ... Pharmacology Research & Perspectives 8 (6), e00674, 2020 | 97 | 2020 |
Mapping polyclonal antibody responses in non-human primates vaccinated with HIV Env trimer subunit vaccines B Nogal, M Bianchi, CA Cottrell, RN Kirchdoerfer, LM Sewall, HL Turner, ... Cell reports 30 (11), 3755-3765. e7, 2020 | 86 | 2020 |
Structural definition of a neutralization-sensitive epitope on the MERS-CoV S1-NTD N Wang, O Rosen, L Wang, HL Turner, LJ Stevens, KS Corbett, ... Cell reports 28 (13), 3395-3405. e6, 2019 | 82 | 2019 |
Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA. 1 attenuation DY Chen, CV Chin, D Kenney, AH Tavares, N Khan, HL Conway, GQ Liu, ... Nature 615 (7950), 143-150, 2023 | 81 | 2023 |
The Ebola virus VP30-NP interaction is a regulator of viral RNA synthesis RN Kirchdoerfer, CL Moyer, DM Abelson, EO Saphire PLoS Pathogens 12 (10), e1005937, 2016 | 81 | 2016 |
Chain dynamics of nascent polypeptides emerging from the ribosome JP Ellis, CK Bakke, RN Kirchdoerfer, LM Jungbauer, S Cavagnero ACS chemical biology 3 (9), 555-566, 2008 | 73 | 2008 |
Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective M Seifert, SC Bera, P Van Nies, RN Kirchdoerfer, A Shannon, TTN Le, ... Elife 10, e70968, 2021 | 66 | 2021 |
Structural basis for ligand recognition and discrimination of a quorum-quenching antibody RN Kirchdoerfer, AL Garner, CE Flack, JM Mee, AR Horswill, KD Janda, ... Journal of biological chemistry 286 (19), 17351-17358, 2011 | 65 | 2011 |
The marburgvirus-neutralizing human monoclonal antibody MR191 targets a conserved site to block virus receptor binding LB King, ML Fusco, AI Flyak, PA Ilinykh, K Huang, B Gunn, ... Cell host & microbe 23 (1), 101-109. e4, 2018 | 58 | 2018 |
Variable lymphocyte receptor recognition of the immunodominant glycoprotein of Bacillus anthracis spores RN Kirchdoerfer, BR Herrin, BW Han, CL Turnbough, MD Cooper, ... Structure 20 (3), 479-486, 2012 | 56 | 2012 |
Structure and immune recognition of the porcine epidemic diarrhea virus spike protein RN Kirchdoerfer, M Bhandari, O Martini, LM Sewall, S Bangaru, KJ Yoon, ... Structure 29 (4), 385-392. e5, 2021 | 55 | 2021 |
Crystal structure of the Marburg virus VP35 oligomerization domain JF Bruhn, RN Kirchdoerfer, SM Urata, S Li, IJ Tickle, G Bricogne, ... Journal of virology 91 (2), 10.1128/jvi. 01085-16, 2017 | 51 | 2017 |