Mauro Alini
Mauro Alini
AO Research Institute Davos
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The human lumbar intervertebral disc: evidence for changes in the biosynthesis and denaturation of the extracellular matrix with growth, maturation, ageing, and degeneration.
J Antoniou, T Steffen, F Nelson, N Winterbottom, AP Hollander, RA Poole, ...
The Journal of clinical investigation 98 (4), 996-1003, 1996
Are animal models useful for studying human disc disorders/degeneration?
M Alini, SM Eisenstein, K Ito, C Little, AA Kettler, K Masuda, J Melrose, ...
European Spine Journal 17 (1), 2-19, 2008
Tissue engineering for articular cartilage repair—the state of the art
B Johnstone, M Alini, M Cucchiarini, GR Dodge, D Eglin, F Guilak, ...
Eur Cell Mater 25 (248), e67, 2013
Compression-induced changes in intervertebral disc properties in a rat tail model
JC Iatridis, PL Mente, IAF Stokes, DD Aronsson, M Alini
Spine 24 (10), 996-1002, 1999
2004 Young Investigator Award Winner: vertebral endplate marrow contact channel occlusions and intervertebral disc degeneration
LM Benneker, PF Heini, M Alini, SE Anderson, K Ito
Spine 30 (2), 167-173, 2005
The potential and limitations of a cell-seeded collagen/hyaluronan scaffold to engineer an intervertebral disc-like matrix
M Alini, W Li, P Markovic, M Aebi, RC Spiro, PJ Roughley
Spine 28 (5), 446-453, 2003
The use of biodegradable polyurethane scaffolds for cartilage tissue engineering: potential and limitations
S Grad, L Kupcsik, K Gorna, S Gogolewski, M Alini
Biomaterials 24 (28), 5163-5171, 2003
Correlation of radiographic and MRI parameters to morphological and biochemical assessment of intervertebral disc degeneration
LM Benneker, PF Heini, SE Anderson, M Alini, K Ito
European spine journal 14 (1), 27-35, 2005
Role and regulation of RUNX2 in osteogenesis
M Bruderer, RG Richards, M Alini, MJ Stoddart
Eur Cell Mater 28 (28), 269-86, 2014
Concise review: Bone marrow‐derived mesenchymal stem cells change phenotype following in vitro culture: implications for basic research and the clinic
JJ Bara, RG Richards, M Alini, MJ Stoddart
Stem cells 32 (7), 1713-1723, 2014
Cartilage and bone metabolism in rheumatoid arthritis. Differences between rapid and slow progression of disease identified by serum markers of cartilage metabolism.
B Månsson, D Carey, M Alini, M Ionescu, LC Rosenberg, AR Poole, ...
The Journal of clinical investigation 95 (3), 1071-1077, 1995
Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc
D Sakai, Y Nakamura, T Nakai, T Mishima, S Kato, S Grad, M Alini, ...
Nature communications 3 (1), 1-11, 2012
Aggrecan degradation in human intervertebral disc and articular cartilage
Biochemical Journal 326 (1), 235-241, 1997
The potential of chitosan-based gels containing intervertebral disc cells for nucleus pulposus supplementation
P Roughley, C Hoemann, E DesRosiers, F Mwale, J Antoniou, M Alini
Biomaterials 27 (3), 388-396, 2006
Diversity of intervertebral disc cells: phenotype and function
G Pattappa, Z Li, M Peroglio, N Wismer, M Alini, S Grad
Journal of anatomy 221 (6), 480-496, 2012
The role of proteoglycans in aging, degeneration and repair of the intervertebral disc
PJ Roughley, M Alini, J Antoniou
Biochemical Society Transactions 30 (6), 869-874, 2002
A phenotypic comparison of intervertebral disc and articular cartilage cells in the rat
CR Lee, D Sakai, T Nakai, K Toyama, J Mochida, M Alini, S Grad
European Spine Journal 16 (12), 2174-2185, 2007
A biological approach to treating disc degeneration: not for today, but maybe for tomorrow
M Alini, PJ Roughley, J Antoniou, T Stoll, M Aebi
Arthroplasty of the Spine, 159-164, 2004
Anabolic and catabolic mRNA levels of the intervertebral disc vary with the magnitude and frequency of in vivo dynamic compression
JJ MacLean, CR Lee, M Alini, JC Iatridis
Journal of Orthopaedic Research 22 (6), 1193-1200, 2004
Effects of immobilization and dynamic compression on intervertebral disc cell gene expression in vivo
JJ MacLean, CR Lee, S Grad, K Ito, M Alini, JC Iatridis
Spine 28 (10), 973-981, 2003
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