The human lumbar intervertebral disc: evidence for changes in the biosynthesis and denaturation of the extracellular matrix with growth, maturation, ageing, and degeneration. J Antoniou, T Steffen, F Nelson, N Winterbottom, AP Hollander, RA Poole, ... The Journal of clinical investigation 98 (4), 996-1003, 1996 | 1048 | 1996 |
Are animal models useful for studying human disc disorders/degeneration? M Alini, SM Eisenstein, K Ito, C Little, AA Kettler, K Masuda, J Melrose, ... European Spine Journal 17 (1), 2-19, 2008 | 657 | 2008 |
Tissue engineering for articular cartilage repair—the state of the art B Johnstone, M Alini, M Cucchiarini, GR Dodge, D Eglin, F Guilak, ... Eur Cell Mater 25 (248), e67, 2013 | 391 | 2013 |
Compression-induced changes in intervertebral disc properties in a rat tail model JC Iatridis, PL Mente, IAF Stokes, DD Aronsson, M Alini Spine 24 (10), 996-1002, 1999 | 330 | 1999 |
2004 Young Investigator Award Winner: vertebral endplate marrow contact channel occlusions and intervertebral disc degeneration LM Benneker, PF Heini, M Alini, SE Anderson, K Ito Spine 30 (2), 167-173, 2005 | 318 | 2005 |
The potential and limitations of a cell-seeded collagen/hyaluronan scaffold to engineer an intervertebral disc-like matrix M Alini, W Li, P Markovic, M Aebi, RC Spiro, PJ Roughley Spine 28 (5), 446-453, 2003 | 316 | 2003 |
The use of biodegradable polyurethane scaffolds for cartilage tissue engineering: potential and limitations S Grad, L Kupcsik, K Gorna, S Gogolewski, M Alini Biomaterials 24 (28), 5163-5171, 2003 | 312 | 2003 |
Correlation of radiographic and MRI parameters to morphological and biochemical assessment of intervertebral disc degeneration LM Benneker, PF Heini, SE Anderson, M Alini, K Ito European spine journal 14 (1), 27-35, 2005 | 309 | 2005 |
Role and regulation of RUNX2 in osteogenesis M Bruderer, RG Richards, M Alini, MJ Stoddart Eur Cell Mater 28 (28), 269-86, 2014 | 303 | 2014 |
Concise review: Bone marrow‐derived mesenchymal stem cells change phenotype following in vitro culture: implications for basic research and the clinic JJ Bara, RG Richards, M Alini, MJ Stoddart Stem cells 32 (7), 1713-1723, 2014 | 299 | 2014 |
Cartilage and bone metabolism in rheumatoid arthritis. Differences between rapid and slow progression of disease identified by serum markers of cartilage metabolism. B Månsson, D Carey, M Alini, M Ionescu, LC Rosenberg, AR Poole, ... The Journal of clinical investigation 95 (3), 1071-1077, 1995 | 283 | 1995 |
Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc D Sakai, Y Nakamura, T Nakai, T Mishima, S Kato, S Grad, M Alini, ... Nature communications 3 (1), 1-11, 2012 | 279 | 2012 |
Aggrecan degradation in human intervertebral disc and articular cartilage R SZTROLOVICS, M ALINI, PJ ROUGHLEY, JS MORT Biochemical Journal 326 (1), 235-241, 1997 | 279 | 1997 |
The potential of chitosan-based gels containing intervertebral disc cells for nucleus pulposus supplementation P Roughley, C Hoemann, E DesRosiers, F Mwale, J Antoniou, M Alini Biomaterials 27 (3), 388-396, 2006 | 275 | 2006 |
Diversity of intervertebral disc cells: phenotype and function G Pattappa, Z Li, M Peroglio, N Wismer, M Alini, S Grad Journal of anatomy 221 (6), 480-496, 2012 | 229 | 2012 |
The role of proteoglycans in aging, degeneration and repair of the intervertebral disc PJ Roughley, M Alini, J Antoniou Biochemical Society Transactions 30 (6), 869-874, 2002 | 229 | 2002 |
A phenotypic comparison of intervertebral disc and articular cartilage cells in the rat CR Lee, D Sakai, T Nakai, K Toyama, J Mochida, M Alini, S Grad European Spine Journal 16 (12), 2174-2185, 2007 | 220 | 2007 |
A biological approach to treating disc degeneration: not for today, but maybe for tomorrow M Alini, PJ Roughley, J Antoniou, T Stoll, M Aebi Arthroplasty of the Spine, 159-164, 2004 | 207 | 2004 |
Anabolic and catabolic mRNA levels of the intervertebral disc vary with the magnitude and frequency of in vivo dynamic compression JJ MacLean, CR Lee, M Alini, JC Iatridis Journal of Orthopaedic Research 22 (6), 1193-1200, 2004 | 202 | 2004 |
Effects of immobilization and dynamic compression on intervertebral disc cell gene expression in vivo JJ MacLean, CR Lee, S Grad, K Ito, M Alini, JC Iatridis Spine 28 (10), 973-981, 2003 | 199 | 2003 |