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George E. Johnson, PhD
George E. Johnson, PhD
Swansea University Medical School, Swansea University.
Verificeret mail på swansea.ac.uk - Startside
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Mechanistic influences for mutation induction curves after exposure to DNA-reactive carcinogens
SH Doak, GJS Jenkins, GE Johnson, E Quick, EM Parry, JM Parry
Cancer research 67 (8), 3904-3911, 2007
2102007
Detection and characterization of mechanisms of action of aneugenic chemicals
EM Parry, JM Parry, C Corso, A Doherty, F Haddad, TF Hermine, ...
Mutagenesis 17 (6), 509-521, 2002
1832002
Radiation-induced transgenerational alterations in genome stability and DNA damage
RC Barber, P Hickenbotham, T Hatch, D Kelly, N Topchiy, GM Almeida, ...
Oncogene 25 (56), 7336-7342, 2006
1672006
Do dose response thresholds exist for genotoxic alkylating agents?
GJS Jenkins, SH Doak, GE Johnson, E Quick, EM Waters, JM Parry
Mutagenesis 20 (6), 389-398, 2005
1412005
Derivation of point of departure (PoD) estimates in genetic toxicology studies and their potential applications in risk assessment
GE Johnson, LG Soeteman‐Hernández, BB Gollapudi, OG Bodger, ...
Environmental and molecular mutagenesis 55 (8), 609-623, 2014
1342014
Quantitative approaches for assessing dose–response relationships in genetic toxicology studies
BB Gollapudi, GE Johnson, LG Hernandez, LH Pottenger, KL Dearfield, ...
Environmental and molecular mutagenesis 54 (1), 8-18, 2013
1322013
A review: the current in vivo models for the discovery and utility of new anti-leishmanial drugs targeting cutaneous leishmaniasis
ER Mears, F Modabber, R Don, GE Johnson
PLoS neglected tropical diseases 9 (9), e0003889, 2015
1232015
IWGT report on quantitative approaches to genotoxicity risk assessment II. Use of point-of-departure (PoD) metrics in defining acceptable exposure limits and assessing human risk
JT MacGregor, R Frötschl, PA White, KS Crump, DA Eastmond, ...
Mutation Research/Genetic Toxicology and Environmental Mutagenesis 783, 66-78, 2015
1202015
IWGT report on quantitative approaches to genotoxicity risk assessment I. Methods and metrics for defining exposure–response relationships and points of departure (PoDs)
JT MacGregor, R Frötschl, PA White, KS Crump, DA Eastmond, ...
Mutation Research/Genetic Toxicology and Environmental Mutagenesis 783, 55-65, 2015
1152015
Mammalian Cell HPRT Gene Mutation Assay: Test Methods
GE Johnson
Genetic Toxicology: Principles and Methods, 55-67, 2012
1152012
Mechanistic investigations of low dose exposures to the genotoxic compounds bisphenol-A and rotenone
GE Johnson, EM Parry
Mutation Research/Genetic Toxicology and Environmental Mutagenesis 651 (1-2 …, 2008
772008
Next generation testing strategy for assessment of genomic damage: A conceptual framework and considerations
KL Dearfield, BB Gollapudi, JC Bemis, RD Benz, GR Douglas, ...
Environmental and Molecular Mutagenesis 58 (5), 264-283, 2017
702017
Non-linear dose–response of DNA-reactive genotoxins: Recommendations for data analysis
GE Johnson, SH Doak, SM Griffiths, EL Quick, DOF Skibinski, ZM Zaïr, ...
Mutation Research/Genetic Toxicology and Environmental Mutagenesis 678 (2 …, 2009
702009
Empirical analysis of BMD metrics in genetic toxicology part I: in vitro analyses to provide robust potency rankings and support MOA determinations
JW Wills, GE Johnson, SH Doak, LG Soeteman-Hernández, W Slob, ...
Mutagenesis 31 (3), 255-263, 2016
662016
The Influence of DNA Repair on Non-Linear Dose Responses for Mutation
AD Thomas, GJS Jenkins, B Kaina, OG Bodger, T Karl-Heinz, PD Lewis, ...
Toxicological Sciences, 2013
652013
Estimating the carcinogenic potency of chemicals from the in vivo micronucleus test
LG Soeteman-Hernández, GE Johnson, W Slob
Mutagenesis 31 (3), 347-358, 2016
602016
A mode-of-action approach for the identification of genotoxic carcinogens
LG Hernández, J Van Benthem, GE Johnson
PLoS One 8 (5), e64532, 2013
542013
Genotoxic thresholds, DNA repair, and susceptibility in human populations
GJS Jenkins, Z Zaïr, GE Johnson, SH Doak
Toxicology 278 (3), 305-310, 2010
512010
Quantitative interpretation of genetic toxicity dose‐response data for risk assessment and regulatory decision‐making: current status and emerging priorities
PA White, AS Long, GE Johnson
Environmental and Molecular Mutagenesis 61 (1), 66-83, 2020
502020
Mutation as a toxicological endpoint for regulatory decision‐making
RH Heflich, GE Johnson, A Zeller, F Marchetti, GR Douglas, KL Witt, ...
Environmental and Molecular Mutagenesis 61 (1), 34-41, 2020
472020
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