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Morten Skøtt Thomsen
Morten Skøtt Thomsen
Principal Scientist, H. Lundbeck A/S
Verified email at lundbeck.com
Title
Cited by
Cited by
Year
Cognitive improvement by activation of α7 nicotinic acetylcholine receptors: from animal models to human pathophysiology
MS Thomsen, HH Hansen, MB Timmerman, JD Mikkelsen
Current pharmaceutical design 16 (3), 323-343, 2010
2662010
The α7 nicotinic acetylcholine receptor ligands methyllycaconitine, NS6740 and GTS-21 reduce lipopolysaccharide-induced TNF-α release from microglia
MS Thomsen, JD Mikkelsen
Journal of neuroimmunology 251 (1-2), 65-72, 2012
1422012
Human secreted Ly-6/uPAR related protein-1 (SLURP-1) is a selective allosteric antagonist of α7 nicotinic acetylcholine receptor
EN Lyukmanova, MA Shulepko, D Kudryavtsev, ML Bychkov, ...
PLoS One 11 (2), e0149733, 2016
872016
α7 Nicotinic acetylcholine receptor activation prevents behavioral and molecular changes induced by repeated phencyclidine treatment
MS Thomsen, DZ Christensen, HH Hansen, JP Redrobe, JD Mikkelsen
Neuropharmacology 56 (6-7), 1001-1009, 2009
872009
Differential immediate and sustained memory enhancing effects of alpha7 nicotinic receptor agonists and allosteric modulators in rats
MS Thomsen, M El-Sayed, JD Mikkelsen
PloS one 6 (11), e27014, 2011
562011
Hippocampal α7 nicotinic acetylcholine receptor levels in patients with schizophrenia, bipolar disorder, or major depressive disorder
MS Thomsen, A Weyn, JD Mikkelsen
Bipolar disorders 13 (7‐8), 701-707, 2011
542011
Functional characterization of α7 nicotinic acetylcholine and NMDA receptor signaling in SH-SY5Y neuroblastoma cells in an ERK phosphorylation assay
MR Elnagar, AB Walls, GK Helal, FM Hamada, MS Thomsen, AA Jensen
European journal of pharmacology 826, 106-113, 2018
532018
α7 and β2 nicotinic acetylcholine receptor subunits form heteromeric receptor complexes that are expressed in the human cortex and display distinct pharmacological properties
MS Thomsen, R Zwart, D Ursu, MM Jensen, LH Pinborg, G Gilmour, J Wu, ...
PloS one 10 (6), e0130572, 2015
512015
Transient inactivation of the neonatal ventral hippocampus impairs attentional set-shifting behavior: reversal with an α7 nicotinic agonist
JM Brooks, ML Pershing, MS Thomsen, JD Mikkelsen, M Sarter, JP Bruno
Neuropsychopharmacology 37 (11), 2476-2486, 2012
502012
Repeated administration of α7 nicotinic acetylcholine receptor (nAChR) agonists, but not positive allosteric modulators, increases α7 nAChR levels in the brain
DZ Christensen, JD Mikkelsen, HH Hansen, MS Thomsen
Journal of neurochemistry 114 (4), 1205-1216, 2010
482010
Functional interaction between Lypd6 and nicotinic acetylcholine receptors
M Arvaniti, MM Jensen, N Soni, H Wang, AB Klein, N Thiriet, LH Pinborg, ...
Journal of neurochemistry 138 (6), 806-820, 2016
402016
Therapeutic improvements expected in the near future for schizophrenia and schizoaffective disorder: an appraisal of phase III clinical trials of schizophrenia-targeted …
RP Garay, L Citrome, L Samalin, CC Liu, MS Thomsen, CU Correll, ...
Expert opinion on pharmacotherapy 17 (7), 921-936, 2016
402016
Type I and II positive allosteric modulators differentially modulate agonist‐induced up‐regulation of α7 nicotinic acetylcholine receptors
MS Thomsen, JD Mikkelsen
Journal of neurochemistry 123 (1), 73-83, 2012
402012
Prostate stem cell antigen interacts with nicotinic acetylcholine receptors and is affected in Alzheimer's disease
MM Jensen, M Arvaniti, JD Mikkelsen, D Michalski, LH Pinborg, W Härtig, ...
Neurobiology of aging 36 (4), 1629-1638, 2015
392015
Secreted isoform of human Lynx1 (SLURP-2): spatial structure and pharmacology of interactions with different types of acetylcholine receptors
EN Lyukmanova, MA Shulepko, ZO Shenkarev, ML Bychkov, ...
Scientific Reports 6 (1), 30698, 2016
362016
Lynx1 and Aβ1–42 bind competitively to multiple nicotinic acetylcholine receptor subtypes
MS Thomsen, M Arvaniti, MM Jensen, MA Shulepko, DA Dolgikh, ...
Neurobiology of aging 46, 13-21, 2016
352016
The 7 Nicotinic Acetylcholine Receptor Complex: One, Two or Multiple Drug Targets?
M S Thomsen, J D Mikkelsen
Current Drug Targets 13 (5), 707-720, 2012
352012
Expression of the Ly-6 family proteins Lynx1 and Ly6H in the rat brain is compartmentalized, cell-type specific, and developmentally regulated
MS Thomsen, B Cinar, MM Jensen, EN Lyukmanova, MA Shulepko, ...
Brain Structure and Function, 1-12, 2013
342013
BDNF downregulates 5-HT2A receptor protein levels in hippocampal cultures
V Trajkovska, MA Santini, AB Marcussen, MS Thomsen, HH Hansen, ...
Neurochemistry international 55 (7), 697-702, 2009
342009
Activation of glucocorticoid receptors increases 5-HT2A receptor levels
V Trajkovska, L Kirkegaard, G Krey, AB Marcussen, MS Thomsen, ...
Experimental neurology 218 (1), 83-91, 2009
332009
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