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| Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire DA Ostrov, BJ Grant, YA Pompeu, J Sidney, M Harndahl, S Southwood, ... Proceedings of the National Academy of Sciences 109 (25), 9959-9964, 2012 | 478 | 2012 |
| Computational Drug Repositioning: From Data to Therapeutics MR Hurle, L Yang, Q Xie, DK Rajpal, P Sanseau, P Agarwal Clinical Pharmacology & Therapeutics, 2013 | 411 | 2013 |
| Systematic drug repositioning based on clinical side-effects L Yang, P Agarwal PloS one 6 (12), e28025, 2011 | 292 | 2011 |
| Drug repositioning for orphan diseases D Sardana, C Zhu, M Zhang, RC Gudivada, L Yang, AG Jegga Briefings in bioinformatics 12 (4), 346-356, 2011 | 270 | 2011 |
| DRAR-CPI: a server for identifying drug repositioning potential and adverse drug reactions via the chemical–protein interactome H Luo, J Chen, L Shi, M Mikailov, H Zhu, K Wang, L He, L Yang Nucleic acids research 39 (suppl_2), W492-W498, 2011 | 249 | 2011 |
| Systematic Prediction of Pharmacodynamic Drug-Drug Interactions through Protein-Protein-Interaction Network J Huang, C Niu, CD Green, L Yang, H Mei, JDJ Han PLOS Computational Biology 9 (3), e1002998, 2013 | 178 | 2013 |
| Metabolomic profiling to identify potential serum biomarkers for schizophrenia and risperidone action J Xuan, G Pan, Y Qiu, L Yang, M Su, Y Liu, J Chen, G Feng, Y Fang, W Jia, ... Journal of proteome research 10 (12), 5433-5443, 2011 | 177 | 2011 |
| Discovery of molecular mechanisms of traditional Chinese medicinal formula Si-Wu-Tang using gene expression microarray and connectivity map Z Wen, Z Wang, S Wang, R Ravula, L Yang, J Xu, C Wang, Z Zuo, ... PloS one 6 (3), e18278, 2011 | 162 | 2011 |
| Systematic evaluation of connectivity map for disease indications J Cheng, L Yang, V Kumar, P Agarwal Genome medicine 6, 1-8, 2014 | 131 | 2014 |
| HLA-B*58:01 allele is associated with augmented risk for both mild and severe cutaneous adverse reactions induced by allopurinol in Han Chinese. LXQ Cao ZH, Wei ZY, Zhu QY, Zhang JY, Yang L, Qin SY Pharmacogenomics.Jul;(10):1193-201 13 (10), 1193-201, 2012 | 130* | 2012 |
| Genetic Polymorphism Analysis of CYP2C19 in Chinese Han Populations from Different Geographic Areas of Mainland China L Chen, S Qin, J Xie, J Tang, L Yang, W Shen, X Zhao, J Du, G He, ... Pharmacogenomics 9 (6), 691-702, 2008 | 124 | 2008 |
| Exploring off-targets and off-systems for adverse drug reactions via chemical-protein interactome—clozapine-induced agranulocytosis as a case study L Yang, K Wang, J Chen, AG Jegga, H Luo, L Shi, C Wan, X Guo, S Qin, ... PLoS computational biology 7 (3), e1002016, 2011 | 119 | 2011 |
| Sex Differences in the Expression of Drug-Metabolizing and Transporter Genes in Human Liver S Leming, N Baitang Journal of Drug Metabolism & Toxicology, 2012 | 117 | 2012 |
| Harvesting candidate genes responsible for serious adverse drug reactions from a chemical-protein interactome L Yang, J Chen, L He PLoS computational biology 5 (7), e1000441, 2009 | 108 | 2009 |
| Prediction of drug-target interactions for drug repositioning only based on genomic expression similarity K Wang, J Sun, S Zhou, C Wan, S Qin, C Li, L He, L Yang PLoS computational biology 9 (11), e1003315, 2013 | 98 | 2013 |
| Amorphous nickel/cobalt tungsten sulfide electrocatalysts for high-efficiency hydrogen evolution reaction L Yang, X Wu, X Zhu, C He, M Meng, Z Gan, PK Chu Applied Surface Science 341, 149-156, 2015 | 83 | 2015 |
| DDI-CPI, a server that predicts drug–drug interactions through implementing the chemical–protein interactome H Luo, P Zhang, H Huang, J Huang, E Kao, L Shi, L He, L Yang Nucleic acids research 42 (W1), W46-W52, 2014 | 81 | 2014 |
| Molecular docking to identify associations between drugs and class I human leukocyte antigens for predicting idiosyncratic drug reactions H Luo, T Du, P Zhou, L Yang, H Mei, H Ng, W Zhang, M Shu, W Tong, ... Combinatorial chemistry & high throughput screening 18 (3), 296-304, 2015 | 76 | 2015 |
| Label-free quantitative proteomic analysis reveals dysfunction of complement pathway in peripheral blood of schizophrenia patients: evidence for the immune hypothesis of … Y Li, K Zhou, Z Zhang, L Sun, J Yang, M Zhang, B Ji, K Tang, Z Wei, G He, ... Molecular bioSystems, 2012 | 75 | 2012 |
Anil JeggaProfessor of Biomedical Informatics, Cincinnati Children's Hospital Medical CenterVerified email at cchmc.org
