Joanna McGouran
Joanna McGouran
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Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
EL Mills, DG Ryan, HA Prag, D Dikovskaya, D Menon, Z Zaslona, ...
Nature 556 (7699), 113-117, 2018
Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation
NP Blackledge, AM Farcas, T Kondo, HW King, JF McGouran, ...
Cell 157 (6), 1445-1459, 2014
KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands
AM Farcas, NP Blackledge, I Sudbery, HK Long, JF McGouran, NR Rose, ...
elife 1, e00205, 2012
Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes
M Altun, HB Kramer, LI Willems, JL McDermott, CA Leach, SJ Goldenberg, ...
Chemistry & biology 18 (11), 1401-1412, 2011
Molecular basis of USP7 inhibition by selective small-molecule inhibitors
AP Turnbull, S Ioannidis, WW Krajewski, A Pinto-Fernandez, C Heride, ...
Nature 550 (7677), 481-486, 2017
Arginine methylation controls growth regulation by E2F‐1
EC Cho, S Zheng, S Munro, G Liu, SM Carr, J Moehlenbrink, YC Lu, ...
The EMBO journal 31 (7), 1785-1797, 2012
Arginine methylation-dependent reader-writer interplay governs growth control by E2F-1
S Zheng, J Moehlenbrink, YC Lu, LP Zalmas, CA Sagum, S Carr, ...
Molecular cell 52 (1), 37-51, 2013
Autophagy limits proliferation and glycolytic metabolism in acute myeloid leukemia
AS Watson, T Riffelmacher, A Stranks, O Williams, J De Boer, K Cain, ...
Cell death discovery 1 (1), 1-10, 2015
DNA modification under mild conditions by Suzuki–Miyaura cross‐coupling for the generation of functional probes
L Lercher, JF McGouran, BM Kessler, CJ Schofield, BG Davis
Angewandte Chemie International Edition 52 (40), 10553-10558, 2013
Deubiquitinating enzyme specificity for ubiquitin chain topology profiled by di-ubiquitin activity probes
JF McGouran, SR Gaertner, M Altun, HB Kramer, BM Kessler
Chemistry & biology 20 (12), 1447-1455, 2013
Functional analysis of AEBP2, a PRC2 Polycomb protein, reveals a Trithorax phenotype in embryonic development and in ESCs
A Grijzenhout, J Godwin, H Koseki, MR Gdula, D Szumska, JF McGouran, ...
Development 143 (15), 2716-2723, 2016
DNA-PKcs and PARP1 bind to unresected stalled DNA replication forks where they recruit XRCC1 to mediate repair
S Ying, Z Chen, AL Medhurst, JA Neal, Z Bao, O Mortusewicz, ...
Cancer research 76 (5), 1078-1088, 2016
Citrullination-acetylation interplay guides E2F-1 activity during the inflammatory response
F Ghari, AM Quirke, S Munro, J Kawalkowska, S Picaud, J McGouran, ...
Science advances 2 (2), e1501257, 2016
RPA activates the XPF‐ERCC 1 endonuclease to initiate processing of DNA interstrand crosslinks
UB Abdullah, JF McGouran, S Brolih, D Ptchelkine, AH El‐Sagheer, ...
The EMBO journal 36 (14), 2047-2060, 2017
A regulatory circuit that involves HR23B and HDAC6 governs the biological response to HDAC inhibitors
M New, H Olzscha, G Liu, O Khan, L Stimson, J McGouran, D Kerr, ...
Cell Death & Differentiation 20 (10), 1306-1316, 2013
The Ugi four-component reaction enables expedient synthesis and comparison of photoaffinity probes
JT Bush, LJ Walport, JF McGouran, IKH Leung, G Berridge, SS van Berkel, ...
Chemical Science 4 (11), 4115-4120, 2013
The PR/SET domain zinc finger protein Prdm4 regulates gene expression in embryonic stem cells but plays a nonessential role in the developing mouse embryo
D Bogani, MAJ Morgan, AC Nelson, I Costello, JF McGouran, BM Kessler, ...
Molecular and cellular biology 33 (19), 3936-3950, 2013
Methods for detection of cytosine and thymine modifications in DNA
M Berney, JF McGouran
Nature Reviews Chemistry 2 (11), 332-348, 2018
Accessible sugars as asymmetric olefin epoxidation organocatalysts: glucosaminide ketones in the synthesis of terminal epoxides
O Boutureira, JF McGouran, RL Stafford, DPG Emmerson, BG Davis
Organic & biomolecular chemistry 7 (20), 4285-4288, 2009
Human platelet protein ubiquitylation and changes following GPVI activation
AJ Unsworth, I Bombik, A Pinto-Fernandez, JF McGouran, R Konietzny, ...
Thrombosis and haemostasis 119 (01), 104-116, 2019
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