| Complementarity between a docking and a high-throughput screen in discovering new cruzain inhibitors RS Ferreira, A Simeonov, A Jadhav, O Eidam, BT Mott, MJ Keiser, ... Journal of medicinal chemistry 53 (13), 4891-4905, 2010 | 268 | 2010 |
| Covalent docking of large libraries for the discovery of chemical probes N London, RM Miller, S Krishnan, K Uchida, JJ Irwin, O Eidam, L Gibold, ... Nature Chemical Biology 10 (12), 1066–1072, 2014 | 257 | 2014 |
| Structural basis of chaperone–subunit complex recognition by the type 1 pilus assembly platform FimD M Nishiyama, R Horst, O Eidam, T Herrmann, O Ignatov, M Vetsch, ... The EMBO journal 24 (12), 2075-2086, 2005 | 141 | 2005 |
| Anguinomycins and derivatives: total syntheses, modeling, and biological evaluation of the inhibition of nucleocytoplasmic transport S Bonazzi, O Eidam, S Güttinger, JY Wach, I Zemp, U Kutay, ... Journal of the American Chemical Society 132 (4), 1432-1442, 2010 | 126 | 2010 |
| Structural and functional insights into the assembly of type 1 pili from Escherichia coli G Capitani, O Eidam, R Glockshuber, MG Grütter Microbes and infection 8 (8), 2284-2290, 2006 | 98 | 2006 |
| Design, synthesis, crystal structures, and antimicrobial activity of sulfonamide boronic acids as β-lactamase inhibitors O Eidam, C Romagnoli, E Caselli, K Babaoglu, DT Pohlhaus, J Karpiak, ... Journal of medicinal chemistry 53 (21), 7852-7863, 2010 | 91 | 2010 |
| Fragment-guided design of subnanomolar β-lactamase inhibitors active in vivo O Eidam, C Romagnoli, G Dalmasso, S Barelier, E Caselli, R Bonnet, ... Proceedings of the National Academy of Sciences 109 (43), 17448-17453, 2012 | 84 | 2012 |
| Infinite kinetic stability against dissociation of supramolecular protein complexes through donor strand complementation C Puorger, O Eidam, G Capitani, D Erilov, MG Grütter, R Glockshuber Structure 16 (4), 631-642, 2008 | 84 | 2008 |
| Increasing chemical space coverage by combining empirical and computational fragment screens S Barelier, O Eidam, I Fish, J Hollander, F Figaroa, R Nachane, JJ Irwin, ... ACS chemical biology 9 (7), 1528-1535, 2014 | 63 | 2014 |
| Quality control of disulfide bond formation in pilus subunits by the chaperone FimC MD Crespo, C Puorger, MA Schärer, O Eidam, MG Grütter, G Capitani, ... Nature chemical biology 8 (8), 707-713, 2012 | 61 | 2012 |
| Analysis of the productivity of DNA encoded libraries O Eidam, AL Satz MedChemComm 7 (7), 1323-1331, 2016 | 53 | 2016 |
| Crystal structure of the ternary FimC–FimFt–FimDN complex indicates conserved pilus chaperone–subunit complex recognition by the usher FimD O Eidam, FSN Dworkowski, R Glockshuber, MG Grütter, G Capitani FEBS letters 582 (5), 651-655, 2008 | 51 | 2008 |
| Homologous ligands accommodated by discrete conformations of a buried cavity M Merski, M Fischer, TE Balius, O Eidam, BK Shoichet Proceedings of the National Academy of Sciences 112 (16), 5039-5044, 2015 | 50 | 2015 |
| Inducers of the endothelial cell barrier identified through chemogenomic screening in genome-edited hPSC-endothelial cells F Roudnicky, JD Zhang, BK Kim, NJ Pandya, Y Lan, L Sach-Peltason, ... Proceedings of the National Academy of Sciences 117 (33), 19854-19865, 2020 | 42 | 2020 |
| Evidence for a novel domain of bacterial outer membrane ushers G Capitani, O Eidam, MG Grütter Proteins: Structure, Function, and Bioinformatics 65 (4), 816-823, 2006 | 26 | 2006 |
| Development and Binding Mode Assessment of N-[4-[2-Propyn-1-yl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-3H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-l-γ … A Tochowicz, S Dalziel, O Eidam, JD O’Connell III, S Griner, ... Journal of medicinal chemistry 56 (13), 5446-5455, 2013 | 17 | 2013 |
| Abstract LBA004: Identification of GSPT1-directed molecular glue degrader (MGD) for the treatment of Myc-driven breast cancer G Gavory, B Fasching, D Bonenfant, A Sadok, A Singh, M Schillo, ... Molecular Cancer Therapeutics 20 (12_Supplement), LBA004-LBA004, 2021 | 3 | 2021 |
| Erratum: Covalent docking of large libraries for the discovery of chemical probes N London, RM Miller, S Krishnan, K Uchida, JJ Irwin, O Eidam, L Gibold, ... Nature Chemical Biology 11 (3), 235-235, 2015 | 2 | 2015 |
| Isoindolinone compounds A Flohr, O Eidam, B Fasching, M Meniconi, A Sadok, R Chopra, ... US Patent App. 17/716,169, 2022 | | 2022 |
| ISOINDOLINONE COMPOUNDS A FLOHR, O EIDAM, B FASCHING, M MENICONI, A SADOK, R CHOPRA, ... WO Patent WO2,021,069,705, 2021 | | 2021 |
