|Distinct Wnt signaling pathways have opposing roles in appendage regeneration|
CL Stoick-Cooper, G Weidinger, KJ Riehle, C Hubbert, MB Major, ...
Development 134 (3), 479-489, 2007
|Wilms tumor suppressor WTX negatively regulates WNT/ß-catenin signaling|
MB Major, ND Camp, JD Berndt, XH Yi, SJ Goldenberg, C Hubbert, ...
science 316 (5827), 1043-1046, 2007
|Activated Wnt/ß-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model|
AJ Chien, EC Moore, AS Lonsdorf, RM Kulikauskas, BG Rothberg, ...
Proceedings of the National Academy of Sciences 106 (4), 1193-1198, 2009
Principles and practice of oncology, 1993
|Common genetic variation within the low-density lipoprotein receptor-related protein 6 and late-onset Alzheimer's disease|
GV De Ferrari, A Papassotiropoulos, T Biechele, FW De-Vrieze, ME Avila, ...
Proceedings of the National Academy of Sciences 104 (22), 9434-9439, 2007
|The Kindler syndrome protein is regulated by transforming growth factor-β and involved in integrin-mediated adhesion|
S Kloeker, MB Major, DA Calderwood, MH Ginsberg, DA Jones, ...
Journal of Biological Chemistry 279 (8), 6824-6833, 2004
|Proteomic analysis of ubiquitin ligase KEAP1 reveals associated proteins that inhibit NRF2 ubiquitination|
BE Hast, D Goldfarb, KM Mulvaney, MA Hast, PF Siesser, F Yan, ...
Cancer research 73 (7), 2199-2210, 2013
|New regulators of Wnt/β-catenin signaling revealed by integrative molecular screening|
MB Major, BS Roberts, JD Berndt, S Marine, J Anastas, N Chung, ...
Science signaling 1 (45), ra12-ra12, 2008
|Small-molecule synergist of the Wnt/β-catenin signaling pathway|
Q Zhang, MB Major, S Takanashi, ND Camp, N Nishiya, EC Peters, ...
Proceedings of the National Academy of Sciences 104 (18), 7444-7448, 2007
|Cancer-derived mutations in KEAP1 impair NRF2 degradation but not ubiquitination|
BE Hast, EW Cloer, D Goldfarb, H Li, PF Siesser, F Yan, V Walter, ...
Cancer research 74 (3), 808-817, 2014
|Wilms tumor gene on X chromosome (WTX) inhibits degradation of NRF2 protein through competitive binding to KEAP1 protein|
ND Camp, RG James, DW Dawson, F Yan, JM Davison, SA Houck, ...
Journal of Biological Chemistry 287 (9), 6539-6550, 2012
|WNT7B mediates autocrine Wnt/β-catenin signaling and anchorage-independent growth in pancreatic adenocarcinoma|
MD Arensman, AN Kovochich, RM Kulikauskas, AR Lay, PT Yang, X Li, ...
Oncogene 33 (7), 899-908, 2014
|BRG1/SMARCA4 inactivation promotes non–small cell lung cancer aggressiveness by altering chromatin organization|
T Orvis, A Hepperla, V Walter, S Song, J Simon, J Parker, MD Wilkerson, ...
Cancer research 74 (22), 6486-6498, 2014
|WIKI4, a novel inhibitor of tankyrase and Wnt/ss-catenin signaling|
RG James, KC Davidson, KA Bosch, TL Biechele, NC Robin, RJ Taylor, ...
PloS one 7 (12), e50457, 2012
|Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1|
JS Harrison, EM Cornett, D Goldfarb, PA DaRosa, ZM Li, F Yan, ...
Elife 5, e17101, 2016
|Bruton’s Tyrosine Kinase Revealed as a Negative Regulator of Wnt–β-Catenin Signaling|
RG James, TL Biechele, WH Conrad, ND Camp, DM Fass, MB Major, ...
Science signaling 2 (72), ra25-ra25, 2009
|Identification of a gadd45β 3′ enhancer that mediates SMAD3-and SMAD4-dependent transcriptional induction by transforming growth factor β|
MB Major, DA Jones
Journal of Biological Chemistry 279 (7), 5278-5287, 2004
|USP6 oncogene promotes Wnt signaling by deubiquitylating Frizzleds|
B Madan, MP Walker, R Young, L Quick, KA Orgel, M Ryan, P Gupta, ...
Proceedings of the National Academy of Sciences 113 (21), E2945-E2954, 2016
|Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase|
TY Kim, PF Siesser, KL Rossman, D Goldfarb, K Mackinnon, F Yan, XH Yi, ...
Molecular and cellular biology 35 (1), 167-181, 2015
|NRF2 activation in cancer: from DNA to protein|
EW Cloer, D Goldfarb, TP Schrank, BE Weissman, MB Major
Cancer research 79 (5), 889-898, 2019