Saturation-transfer difference (STD) NMR: a simple and fast method for ligand screening and characterization of protein binding A Viegas, J Manso, FL Nobrega, EJ Cabrita Journal of chemical Education 88 (7), 990-994, 2011 | 410 | 2011 |
Targeting mechanisms of tailed bacteriophages FL Nobrega, M Vlot, PA de Jonge, LL Dreesens, HJE Beaumont, ... Nature Reviews Microbiology, 2018 | 397 | 2018 |
Revisiting phage therapy: new applications for old resources FL Nobrega, AR Costa, LD Kluskens, J Azeredo Trends in microbiology 23 (4), 185-191, 2015 | 339 | 2015 |
Molecular and Evolutionary Determinants of Bacteriophage Host Range PA de Jonge, FL Nobrega, SJJ Brouns, BE Dutilh Trends in Microbiology, 2018 | 336 | 2018 |
Molecular aspects and comparative genomics of bacteriophage endolysins H Oliveira, LDR Melo, SB Santos, FL Nóbrega, EC Ferreira, N Cerca, ... Journal of virology 87 (8), 4558-4570, 2013 | 291 | 2013 |
Global phylogeography and ancient evolution of the widespread human gut virus crAssphage R Edwards, ..., FL Nobrega, ..., BE Dutilh Nature Microbiology, 2019 | 218 | 2019 |
Bowel biofilms: tipping points between a healthy and compromised gut? HLP Tytgat, FL Nobrega, J van der Oost, WM de Vos Trends in microbiology 27 (1), 17-25, 2019 | 132 | 2019 |
Cas4 Facilitates PAM-Compatible Spacer Selection during CRISPR Adaptation SJJB SN Kieper, C Almendros, J Behler, RE McKenzie, FL Nobrega, AC Haagsma ... Cell Reports 22 (13), p3377–3384, 2018 | 120 | 2018 |
Genetically manipulated phages with improved pH resistance for oral administration in veterinary medicine FL Nobrega, AR Costa, JF Santos, MF Siliakus, JWM Van Lent, ... Scientific reports 6 (1), 39235, 2016 | 96 | 2016 |
Identification and classification of antiviral defence systems in bacteria and archaea with PADLOC reveals new system types LJ Payne, TC Todeschini, Y Wu, BJ Perry, CW Ronson, PC Fineran, ... Nucleic Acids Research, 2021 | 95 | 2021 |
Keeping CRISPR in check: diverse mechanisms of phage-encoded anti-CRISPRs D Trasanidou, AS Gerós, P Mohanraju, AC Nieuwenweg, FL Nobrega, ... FEMS Microbiology Letters, 2019 | 83 | 2019 |
Exploiting Bacteriophage Proteomes: The Hidden Biotechnological Potential SB Santos, AR Costa, C Carvalho, FL Nobrega, J Azeredo Trends in Biotechnology, 2018 | 56 | 2018 |
Development of molecularly imprinted co-polymeric devices for controlled delivery of flufenamic acid using supercritical fluid technology MS Da Silva, FL Nobrega, A Aguiar-Ricardo, EJ Cabrita, T Casimiro The Journal of Supercritical Fluids 58 (1), 150-157, 2011 | 49 | 2011 |
Cas4–Cas1 fusions drive efficient PAM selection and control CRISPR adaptation C Almendros, FL Nobrega, RE McKenzie, SJJ Brouns Nucleic Acids Research, 2019 | 44 | 2019 |
Gut virome profiling identifies a widespread bacteriophage family associated with metabolic syndrome PA de Jonge, K Wortelboer, TPM Scheithauer, BJH van den Born, ... Nature communications 13 (1), 3594, 2022 | 41 | 2022 |
Prophages are associated with extensive, tolerated CRISPR-Cas auto-immunity FL Nobrega, H Walinga, BE Dutilh, SJJ Brouns Nucleic Acids Research, 2020 | 41 | 2020 |
Selection of novel peptides homing the 4T1 CELL line: exploring alternative targets for triple negative breast cancer VL Silva, D Ferreira, FL Nobrega, IM Martins, LD Kluskens, LR Rodrigues PloS one 11 (8), e0161290, 2016 | 39 | 2016 |
Building pangenome graphs E Garrison, A Guarracino, S Heumos, F Villani, Z Bao, L Tattini, ... bioRxiv, 2023 | 38 | 2023 |
Rational Identification of a Colorectal Cancer Targeting Peptide through Phage Display D Ferreira, AP Silva, FL Nobrega, IM Martins, C Barbosa-Matos, S Granja, ... Scientific Reports, 2019 | 31 | 2019 |
CRISPR-based DNA and RNA detection with liquid-liquid phase separation WK Spoelstra, JM Jacques, R Gonzalez-Linares, FL Nobrega, ... Biophysical Journal 120 (7), 1198-1209, 2021 | 25 | 2021 |