Gertrud Hjortø
Gertrud Hjortø
Associate Professor
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Tissue factor-factor VIIa–specific up-regulation of IL-8 expression in MDA-MB-231 cells is mediated by PAR-2 and results in increased cell migration
GM Hjortoe, LC Petersen, T Albrektsen, BB Sorensen, PL Norby, ...
Blood 103 (8), 3029-3037, 2004
Transcriptional program induced by factor VIIa‐tissue factor, PAR1 and PAR2 in MDA‐MB‐231 cells
T Albrektsen, BB Sørensen, GM Hjortø, J Fleckner, LVM Rao, LC Petersen
Journal of thrombosis and haemostasis 5 (8), 1588-1597, 2007
In-chip fabrication of free-form 3D constructs for directed cell migration analysis
MH Olsen, GM Hjortø, M Hansen, Ö Met, IM Svane, NB Larsen
Lab on a Chip 13 (24), 4800-4809, 2013
Differential CCR7 targeting in dendritic cells by three naturally occurring CC-chemokines
GM Hjortø, O Larsen, A Steen, V Daugvilaite, C Berg, S Fares, M Hansen, ...
Frontiers in immunology 7, 568, 2016
Rationally designed chemokine-based toxin targeting the viral G protein-coupled receptor US28 potently inhibits cytomegalovirus infection in vivo
K Spiess, MG Jeppesen, M Malmgaard-Clausen, K Krzywkowski, K Dulal, ...
Proceedings of the National Academy of Sciences 112 (27), 8427-8432, 2015
Comparison of clinical grade type 1 polarized and standard matured dendritic cells for cancer immunotherapy
M Hansen, GM Hjortø, M Donia, Ö Met, NB Larsen, MH Andersen, ...
Vaccine 31 (4), 639-646, 2013
Biased signaling of G protein-coupled receptors–From a chemokine receptor CCR7 perspective
AS Jørgensen, MM Rosenkilde, GM Hjortø
General and comparative endocrinology 258, 4-14, 2018
Functional identification and monitoring of individual α and β cells in cultured mouse islets of Langerhans
GM Hjortø, GM Hagel, BR Terry, O Thastrup, POG Arkhammar
Acta diabetologica 41 (4), 185-193, 2004
Factor VIIa binding and internalization in hepatocytes
G Hjortoe, BB Sorensen, LC Petersen, LVM Rao
Journal of Thrombosis and Haemostasis 3 (10), 2264-2273, 2005
Probing biased signaling in chemokine receptors
RM Amarandi, GM Hjortø, MM Rosenkilde, S Karlshøj
Methods in enzymology 570, 155-186, 2016
Human cytomegalovirus chemokine receptor US28 induces migration of cells on a CX3CL1-presenting surface
GM Hjortø, K Kiilerich-Pedersen, D Selmeczi, TN Kledal, NB Larsen
Journal of General Virology 94 (5), 1111-1120, 2013
Factor VIIa/tissue factor-dependent gene regulation and pro-coagulant activity: effect of factor VIIa concentration
LC Petersen, T Albrektsen, GM Hjortø, M Kjalke, SE Bjørn, BB Sørensen
Thrombosis and haemostasis 98 (10), 909-911, 2007
Signaling via G proteins mediates tumorigenic effects of GPR87
KN Arfelt, S Fares, AH Sparre-Ulrich, GM Hjortø, LS Gasbjerg, ...
Cellular Signalling 30, 9-18, 2017
Generating substrate bound functional chemokine gradients in vitro
GM Hjortø, M Hansen, NB Larsen, TN Kledal
Biomaterials 30 (29), 5305-5311, 2009
Autocrine CCL19 blocks dendritic cell migration toward weak gradients of CCL21
M Hansen, Ö Met, NB Larsen, MM Rosenkilde, MH Andersen, IM Svane, ...
Cytotherapy 18 (9), 1187-1196, 2016
Discovery and characterization of biased allosteric agonists of the chemokine receptor CXCR3
L Milanos, R Brox, T Frank, G Poklukar, R Palmisano, R Waibel, ...
Journal of Medicinal Chemistry 59 (5), 2222-2243, 2016
CCL19 with CCL21‐tail displays enhanced glycosaminoglycan binding with retained chemotactic potency in dendritic cells
AS Jørgensen, PE Adogamhe, JM Laufer, DF Legler, CT Veldkamp, ...
Journal of leukocyte biology 104 (2), 401-411, 2018
Arrestin‐independent constitutive endocytosis of GPR125/ADGRA3
K Spiess, SO Bagger, LJ Torz, KHR Jensen, AL Walser, JM Kvam, ...
Annals of the New York Academy of Sciences 1456 (1), 186-199, 2019
Biased signaling of CCL21 and CCL19 does not rely on N-terminal differences, but markedly on the chemokine core domains and extracellular loop 2 of CCR7
AS Jørgensen, O Larsen, E Uetz-von Allmen, M Lückmann, DF Legler, ...
Frontiers in immunology 10, 2156, 2019
GLP-1 Val8: A biased GLP-1R agonist with altered binding kinetics and impaired release of pancreatic hormones in rats
WJC van der Velden, FX Smit, CB Christiansen, TC Møller, GM Hjortø, ...
ACS pharmacology & translational science 4 (1), 296-313, 2021
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