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Stephen Edwards
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An integrative genomics approach to infer causal associations between gene expression and disease
EE Schadt, J Lamb, X Yang, J Zhu, S Edwards, D GuhaThakurta, ...
Nature genetics 37 (7), 710-717, 2005
12162005
Variations in DNA elucidate molecular networks that cause disease
Y Chen, J Zhu, PY Lum, X Yang, S Pinto, DJ MacNeil, C Zhang, J Lamb, ...
Nature 452 (7186), 429-435, 2008
10622008
Experimental annotation of the human genome using microarray technology
DD Shoemaker, EE Schadt, CD Armour, YD He, P Garrett-Engele, ...
Nature 409 (6822), 922-927, 2001
6192001
Genetic inheritance of gene expression in human cell lines
SA Monks, A Leonardson, H Zhu, P Cundiff, P Pietrusiak, S Edwards, ...
The American Journal of Human Genetics 75 (6), 1094-1105, 2004
4712004
Dark matter in the genome: evidence of widespread transcription detected by microarray tiling experiments
JM Johnson, S Edwards, D Shoemaker, EE Schadt
TRENDS in Genetics 21 (2), 93-102, 2005
4462005
A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility
MP Keller, YJ Choi, P Wang, DB Davis, ME Rabaglia, AT Oler, ...
Genome research 18 (5), 706-716, 2008
3982008
Applying adverse outcome pathways (AOPs) to support integrated approaches to testing and assessment (IATA)
KE Tollefsen, S Scholz, MT Cronin, SW Edwards, J de Knecht, K Crofton, ...
Regulatory Toxicology and Pharmacology 70 (3), 629-640, 2014
3452014
Endocrine disrupting chemicals in fish: developing exposure indicators and predictive models of effects based on mechanism of action
GT Ankley, DC Bencic, MS Breen, TW Collette, RB Conolly, ND Denslow, ...
Aquatic Toxicology 92 (3), 168-178, 2009
3142009
An integrative genomics approach to the reconstruction of gene networks in segregating populations
J Zhu, PY Lum, J Lamb, D GuhaThakurta, SW Edwards, R Thieringer, ...
Cytogenetic and genome research 105 (2-4), 363-374, 2004
2832004
Genes, themes and microarrays
H Shatkay, S Edwards, WJ Wilbur, M Boguski
Proc. Int. Conf. Intell. Syst. Mol. Biol 8, 317-327, 2000
2502000
Increasing scientific confidence in adverse outcome pathways: application of tailored Bradford-Hill considerations for evaluating weight of evidence
RA Becker, GT Ankley, SW Edwards, SW Kennedy, I Linkov, B Meek, ...
Regulatory Toxicology and Pharmacology 72 (3), 514-537, 2015
2452015
Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits
M Mehrabian, H Allayee, J Stockton, PY Lum, TA Drake, LW Castellani, ...
Nature genetics 37 (11), 1224-1233, 2005
2422005
Synthesis of redox derivatives of lysine and related peptides containing phenothiazine or tris (2, 2′‐bipyridine) ruthenium (II)
BM PEEK, GT ROSS, SW EDWARDS, GJ MEYER, TJ MEYER, ...
International journal of peptide and protein research 38 (2), 114-123, 1991
2121991
Adverse outcome pathways—organizing toxicological information to improve decision making
SW Edwards, YM Tan, DL Villeneuve, ME Meek, CA McQueen
Journal of Pharmacology and Experimental Therapeutics 356 (1), 170-181, 2016
1992016
Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels
AC Cervino, G Li, S Edwards, J Zhu, C Laurie, G Tokiwa, PY Lum, S Wang, ...
Genomics 86 (5), 505-517, 2005
1592005
A comprehensive transcript index of the human genome generated using microarrays and computational approaches
EE Schadt, SW Edwards, D GuhaThakurta, D Holder, L Ying, V Svetnik, ...
Genome biology 5, 1-17, 2004
1462004
Completing the link between exposure science and toxicology for improved environmental health decision making: the aggregate exposure pathway framework
JG Teeguarden, YM Tan, SW Edwards, JA Leonard, KA Anderson, ...
Environmental Science & Technology 50 (9), 4579-4586, 2016
1252016
Systems biology and mode of action based risk assessment
SW Edwards, RJ Preston
Toxicological Sciences 106 (2), 312-318, 2008
1222008
Localization of G-protein-coupled receptors in health and disease
SW Edwards, CM Tan, LE Limbird
Trends in Pharmacological Sciences 21 (8), 304-308, 2000
1082000
Microarray standard data set and figures of merit for comparing data processing methods and experiment designs
YD He, H Dai, EE Schadt, G Cavet, SW Edwards, SB Stepaniants, ...
Bioinformatics 19 (8), 956-965, 2003
1062003
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