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David Largaespada
David Largaespada
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Verificeret mail på umn.edu
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Pluripotency of mesenchymal stem cells derived from adult marrow
Y Jiang, BN Jahagirdar, RL Reinhardt, RE Schwartz, CD Keene, ...
Nature 418 (6893), 41-49, 2002
87052002
Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
AV Biankin, N Waddell, KS Kassahn, MC Gingras, LB Muthuswamy, ...
Nature 491 (7424), 399-405, 2012
22012012
Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma
I Varela, P Tarpey, K Raine, D Huang, CK Ong, P Stephens, H Davies, ...
Nature 469 (7331), 539-542, 2011
14042011
Recurrent R-spondin fusions in colon cancer
S Seshagiri, EW Stawiski, S Durinck, Z Modrusan, EE Storm, CB Conboy, ...
Nature 488 (7413), 660-664, 2012
10852012
Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice
DJ Rawlings, DC Saffran, S Tsukada, DA Largaespada, JC Grimaldi, ...
Science 261 (5119), 358-361, 1993
10321993
Lymphotactin: a cytokine that represents a new class of chemokine
GS Kelner, J Kennedy, KB Bacon, S Kleyensteuber, DA Largaespada, ...
Science 266 (5189), 1395-1399, 1994
9001994
PVT1 dependence in cancer with MYC copy-number increase
YY Tseng, BS Moriarity, W Gong, R Akiyama, A Tiwari, H Kawakami, ...
Nature 512 (7512), 82-86, 2014
7422014
Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia
T Nakamura, DA Largaespada, MP Lee, LA Johnson, K Ohyashiki, ...
Nature genetics 12 (2), 154-158, 1996
6011996
Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system
AJ Dupuy, K Akagi, DA Largaespada, NG Copeland, NA Jenkins
Nature 436 (7048), 221-226, 2005
5762005
Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells
P Kebriaei, H Singh, MH Huls, MJ Figliola, R Bassett, S Olivares, B Jena, ...
The Journal of clinical investigation 126 (9), 3363-3376, 2016
5312016
Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: Formation of a functional heteromeric complex requires interleukin 7 receptor
LS Park, U Martin, K Garka, B Gliniak, JP Di Santo, W Muller, ...
The Journal of experimental medicine 192 (5), 659-670, 2000
5242000
Clonal selection drives genetic divergence of metastatic medulloblastoma
X Wu, PA Northcott, A Dubuc, AJ Dupuy, DJH Shih, H Witt, S Croul, ...
Nature 482 (7386), 529-533, 2012
4852012
Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse
LS Collier, CM Carlson, S Ravimohan, AJ Dupuy, DA Largaespada
Nature 436 (7048), 272-276, 2005
4702005
Gene transfer into genomes of human cells by the sleeping beauty transposon system
AM Geurts, Y Yang, KJ Clark, G Liu, Z Cui, AJ Dupuy, JB Bell, ...
Molecular Therapy 8 (1), 108-117, 2003
4412003
A transposon-based genetic screen in mice identifies genes altered in colorectal cancer
TK Starr, R Allaei, KAT Silverstein, RA Staggs, AL Sarver, TL Bergemann, ...
Science 323 (5922), 1747-1750, 2009
3982009
Harnessing a high cargo-capacity transposon for genetic applications in vertebrates
D Balciunas, KJ Wangensteen, A Wilber, J Bell, A Geurts, S Sivasubbu, ...
PLoS genetics 2 (11), e169, 2006
3662006
Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias
T Nakamura, DA Largaespada, JD Shaughnessy Jr, NA Jenkins, ...
Nature genetics 12 (2), 149-153, 1996
3601996
Nf1 deficiency causes Ras-Dediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia
DA Largaespada, CI Brannan, NA Jenkins, NG Copeland
Nature genetics 12 (2), 137-143, 1996
3551996
Divergent clonal selection dominates medulloblastoma at recurrence
AS Morrissy, L Garzia, DJH Shih, S Zuyderduyn, X Huang, P Skowron, ...
Nature 529 (7586), 351-357, 2016
3472016
The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma
PA Pérez-Mancera, AG Rust, L Van Der Weyden, G Kristiansen, A Li, ...
Nature 486 (7402), 266-270, 2012
3412012
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Artikler 1–20