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Hartmuth C. Kolb
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Click chemistry: diverse chemical function from a few good reactions
HC Kolb, MG Finn, KB Sharpless
Angewandte Chemie International Edition 40 (11), 2004-2021, 2001
172402001
Catalytic asymmetric dihydroxylation
HC Kolb, MS VanNieuwenhze, KB Sharpless
Chemical Reviews 94 (8), 2483-2547, 1994
47671994
The growing impact of click chemistry on drug discovery
HC Kolb, KB Sharpless
Drug discovery today 8 (24), 1128-1137, 2003
41272003
“On water”: unique reactivity of organic compounds in aqueous suspension
S Narayan, J Muldoon, MG Finn, VV Fokin, HC Kolb, KB Sharpless
Angewandte Chemie 117 (21), 3339-3343, 2005
18882005
Click‐Chemie: diverse chemische Funktionalität mit einer Handvoll guter Reaktionen
HC Kolb, MG Finn, KB Sharpless
Angewandte Chemie 113 (11), 2056-2075, 2001
16422001
Early clinical PET imaging results with the novel PHF-tau radioligand [F-18]-T807
DT Chien, S Bahri, AK Szardenings, JC Walsh, F Mu, MY Su, WR Shankle, ...
Journal of Alzheimer's Disease 34 (2), 457-468, 2013
7312013
Multistep synthesis of a radiolabeled imaging probe using integrated microfluidics
CC Lee, G Sui, A Elizarov, CJ Shu, YS Shin, AN Dooley, J Huang, ...
Science 310 (5755), 1793-1796, 2005
6632005
Inhibitors of HIV-1 protease by using in situ click chemistry
M Whiting, J Muldoon, YC Lin, SM Silverman, W Lindstrom, AJ Olson, ...
Angewandte Chemie (International Ed. in English) 45 (9), 1435-1439, 2006
6512006
In situ click chemistry: enzyme inhibitors made to their own specifications
R Manetsch, A Krasiński, Z Radić, J Raushel, P Taylor, KB Sharpless, ...
Journal of the American Chemical Society 126 (40), 12809-12818, 2004
5972004
[18F] T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease
CF Xia, J Arteaga, G Chen, U Gangadharmath, LF Gomez, D Kasi, C Lam, ...
Alzheimer's & Dementia 9 (6), 666-676, 2013
5282013
In situ selection of lead compounds by click chemistry: target-guided optimization of acetylcholinesterase inhibitors
A Krasiński, Z Radić, R Manetsch, J Raushel, P Taylor, KB Sharpless, ...
Journal of the American Chemical Society 127 (18), 6686-6692, 2005
4642005
The clinical importance of assessing tumor hypoxia: relationship of tumor hypoxia to prognosis and therapeutic opportunities
JC Walsh, A Lebedev, E Aten, K Madsen, L Marciano, HC Kolb
Antioxidants & redox signaling 21 (10), 1516-1554, 2014
4322014
A simplified procedure for the stereospecific transformation of 1, 2-diols into epoxides
HC Kolb, KB Sharpless
Tetrahedron 48 (48), 10515-10530, 1992
3961992
Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation
Y Bourne, HC Kolb, Z Radić, KB Sharpless, P Taylor, P Marchot
Proceedings of the National Academy of Sciences 101 (6), 1449-1454, 2004
3952004
In situ click chemistry: enzyme‐generated inhibitors of carbonic anhydrase II
VP Mocharla, B Colasson, LV Lee, S Röper, KB Sharpless, CH Wong, ...
Angewandte Chemie 117 (1), 118-122, 2005
3362005
Improved enantioselectivity in asymmetric dihydroxylations of terminal olefins using pyrimidine ligands
GA Crispino, KS Jeong, HC Kolb, ZM Wang, D Xu, KB Sharpless
The Journal of Organic Chemistry 58 (15), 3785-3786, 1993
3251993
Toward an understanding of the high enantioselectivity in the osmium-catalyzed asymmetric dihydroxylation (AD). 1. Kinetics
HC Kolb, PG Andersson, KB Sharpless
Journal of the American Chemical Society 116 (4), 1278-1291, 1994
3181994
Cerebrospinal fluid p-tau217 performs better than p-tau181 as a biomarker of Alzheimer’s disease
S Janelidze, E Stomrud, R Smith, S Palmqvist, N Mattsson, DC Airey, ...
Nature communications 11 (1), 1683, 2020
3062020
Early clinical PET imaging results with the novel PHF-tau radioligand [F18]-T808
DT Chien, AK Szardenings, S Bahri, JC Walsh, F Mu, C Xia, WR Shankle, ...
Journal of Alzheimer's Disease 38 (1), 171-184, 2014
3042014
A highly selective and specific PET tracer for imaging of tau pathologies
W Zhang, J Arteaga, DK Cashion, G Chen, U Gangadharmath, LF Gomez, ...
Journal of Alzheimer's Disease 31 (3), 601-612, 2012
2312012
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Articles 1–20