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Yun Chen
Yun Chen
[current] Lundbeck, [previous] University of Copenhagen
Verificeret mail på lundbeck.com
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An atlas of active enhancers across human cell types and tissues
R Andersson, C Gebhard, I Miguel-Escalada, I Hoof, J Bornholdt, M Boyd, ...
Nature 507 (7493), 455-461, 2014
25912014
A promoter-level mammalian expression atlas
Nature 507 (7493), 462-470, 2014
16902014
Polyadenylation site–induced decay of upstream transcripts enforces promoter directionality
E Ntini, AI Järvelin, J Bornholdt, Y Chen, M Boyd, M Jørgensen, ...
Nature structural & molecular biology 20 (8), 923-928, 2013
3002013
Identification of a nuclear exosome decay pathway for processed transcripts
N Meola, M Domanski, E Karadoulama, Y Chen, C Gentil, D Pultz, ...
Molecular cell 64 (3), 520-533, 2016
2282016
Human nonsense-mediated RNA decay initiates widely by endonucleolysis and targets snoRNA host genes
S Lykke-Andersen, Y Chen, BR Ardal, B Lilje, J Waage, A Sandelin, ...
Genes & development 28 (22), 2498-2517, 2014
1892014
Biogenic mechanisms and utilization of small RNAs derived from human protein-coding genes
E Valen, P Preker, PR Andersen, X Zhao, Y Chen, C Ender, A Dueck, ...
Nature structural & molecular biology 18 (9), 1075-1082, 2011
1282011
Cross species comparison of C/EBPα and PPARγ profiles in mouse and human adipocytes reveals interdependent retention of binding sites
SF Schmidt, M Jørgensen, Y Chen, R Nielsen, A Sandelin, S Mandrup
BMC genomics 12, 1-16, 2011
1082011
Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies
M Boyd, M Thodberg, M Vitezic, J Bornholdt, K Vitting-Seerup, Y Chen, ...
Nature communications 9 (1), 1661, 2018
872018
Principles for RNA metabolism and alternative transcription initiation within closely spaced promoters
Y Chen, AA Pai, J Herudek, M Lubas, N Meola, AI Järvelin, R Andersson, ...
Nature genetics 48 (9), 984-994, 2016
782016
Human gene promoters are intrinsically bidirectional
R Andersson, Y Chen, L Core, JT Lis, A Sandelin, TH Jensen
Molecular cell 60 (3), 346-347, 2015
682015
Prediction of RNA Polymerase II recruitment, elongation and stalling from histone modification data
Y Chen, M Jørgensen, R Kolde, X Zhao, B Parker, E Valen, J Wen, ...
BMC genomics 12, 1-16, 2011
452011
The RNA exosome contributes to gene expression regulation during stem cell differentiation
M Lloret-Llinares, E Karadoulama, Y Chen, LA Wojenski, GJ Villafano, ...
Nucleic Acids Research 46 (21), 11502-11513, 2018
442018
Comprehensive profiling of the fission yeast transcription start site activity during stress and media response
M Thodberg, A Thieffry, J Bornholdt, M Boyd, C Holmberg, A Azad, ...
Nucleic acids research 47 (4), 1671-1691, 2019
342019
On-the-fly selection of cell-specific enhancers, genes, miRNAs and proteins across the human body using SlideBase
H Ienasescu, K Li, R Andersson, M Vitezic, S Rennie, Y Chen, ...
Database 2016, baw144, 2016
252016
Lactobacillus rhamnosus GG genomic and phenotypic stability in an industrial production process
M Stage, A Wichmann, M Jørgensen, NI Vera-Jimenéz, M Wielje, ...
Applied and environmental microbiology 86 (6), e02780-19, 2020
192020
Dietary control of skin lipid composition and microbiome
KS Moestrup, Y Chen, T Schepeler, PJ Schweiger, KB Jensen
The Journal of investigative dermatology 138 (5), 1225-1228, 2018
192018
Relation between NOD2 genotype and changes in innate signaling in Crohn’s disease on mRNA and miRNA levels
Y Chen, M Salem, M Boyd, J Bornholdt, Y Li, M Coskun, JB Seidelin, ...
NPJ Genomic Medicine 2 (1), 3, 2017
112017
Personalized B cell response to the Lactobacillus rhamnosus GG probiotic in healthy human subjects: a randomized trial
J Bornholdt, C Broholm, Y Chen, A Rago, S Sloth, J Hendel, C Melsæther, ...
Gut Microbes 12 (1), 1854639, 2020
62020
Identification of promoters and enhancers induced by carbon nanotube exposure
J Bornholdt, B Lilje, AT Saber, M Boyd, M Jørgensen, Y Chen, M Vitezic, ...
First Annual Danish Bioinformatics Conference, 2015
2015
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Artikler 1–19