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Timothy D. Knab
Timothy D. Knab
Metrum Research Group
Verified email at pitt.edu
Title
Cited by
Cited by
Year
Positive charge of “sticky” peptides and proteins impedes release from negatively charged PLGA matrices
SC Balmert, AC Zmolek, AJ Glowacki, TD Knab, SN Rothstein, ...
Journal of materials chemistry B 3 (23), 4723-4734, 2015
412015
A quantitative modeling and simulation framework to support candidate and dose selection of anti‐SARS‐CoV‐2 monoclonal antibodies to advance bamlanivimab into a first‐in‐human …
E Chigutsa, E Jordie, M Riggs, A Nirula, A Elmokadem, T Knab, JY Chien
Clinical Pharmacology & Therapeutics 111 (3), 595-604, 2022
192022
A systems approach to modeling drug release from polymer microspheres to accelerate in vitro to in vivo translation
TD Knab, SR Little, RS Parker
Journal of controlled release 211, 74-84, 2015
192015
Zone model predictive control and moving horizon estimation for the regulation of blood glucose in critical care patients
TD Knab, G Clermont, RS Parker
IFAC-PapersOnLine 48 (8), 1002-1007, 2015
172015
A “virtual patient” cohort and mathematical model of glucose dynamics in critical care
TD Knab, G Clermont, RS Parker
IFAC-PapersOnLine 49 (26), 1-7, 2016
112016
Modeling glucose and subcutaneous insulin dynamics in critical care
A Pritchard-Bell, G Clermont, TD Knab, J Maalouf, M Vilkhovoy, RS Parker
Control Engineering Practice 58, 268-275, 2017
92017
CD19 expression by IHC alone is not a predictor of response to loncastuximab tesirine: results from the LOTIS-2 clinical trial and quantitative systems pharmacology modeling
PF Caimi, M Hamadani, C Carlo-Stella, M Nickaeen, E Jordie, K Utsey, ...
Blood 140 (Supplement 1), 9548-9550, 2022
62022
Bayesian pbpk modeling using r/stan/torsten and julia/sciml/turing. jl
A Elmokadem, Y Zhang, T Knab, E Jordie, WR Gillespie
CPT: Pharmacometrics & Systems Pharmacology 12 (3), 300-310, 2023
52023
Landscape analysis for a neonatal disease progression model of bronchopulmonary dysplasia: Leveraging clinical trial experience and real-world data
JS Barrett, M Cala Pane, T Knab, W Roddy, J Beusmans, E Jordie, ...
Frontiers in Pharmacology 13, 988974, 2022
32022
Toxicity-centric cancer chemotherapy treatment design
JT Liparulo, TD Knab, RS Parker
IFAC-PapersOnLine 53 (2), 16353-16358, 2020
32020
The impact of a responsive endogenous pancreas in critical care glucose control
RS Parker, TD Knab, G Clermont
2018 Annual American Control Conference (ACC), 3595-3601, 2018
32018
Quantitative systems pharmacology modeling of loncastuximab tesirine combined with mosunetuzumab and glofitamab helps guide dosing for patients with DLBCL
Y Li, AK Wilkins, T Knab, JP Boni
Cancer Research 84 (6_Supplement), 875-875, 2024
2024
In relapsed or refractory diffuse large B‐cell lymphoma, CD19 expression by immunohistochemistry alone is not a predictor of response to loncastuximab tesirine
PF Caimi, M Hamadani, C Carlo‐Stella, M Nickaeen, E Jordie, K Utsey, ...
Ejhaem 5 (1), 76-83, 2024
2024
Dosing regimen optimisation for oseltamivir in immunocompromised paediatric patients with influenza: Extrapolation of efficacy
EB Jordie, L Gibiansky, T Knab, A Lemenuel‐Diot, P Ravva, E Zwanziger, ...
British Journal of Clinical Pharmacology 88 (3), 1189-1201, 2022
2022
Model-Based Closed-Loop Glucose Control in Critical Illness
TD Knab
University of Pittsburgh, 2017
2017
AnOpenSourcePackageSuiteinJuliatoFacilitateQSPModelingandSimulation
T Knab, E Jordie, M Riggs, A Elmokadem
Exploring the Influence of Bispecific Antibody Mechanisms on In Vitro Dose Response: Insights from an Open-Science Quantitative Systems Pharmacology Model in Julia
K Utsey, E Jordie, T Knab, E Sobie, AK Wilkins
A multi-organ integrated QSP model for hematopoietic stem cell differentiation to predict the immune cell reconstitution in ex-vivo gene therapy
Y Li, E Jordie, T Knab
Deep QSP Modeling: Leveraging Machine Learning for QSP Model Development and Evaluation
A Elmokadem, T Knab, E Jordie, Y Li
A Clinical Quantitative Systems Pharmacology Framework Describing Loncastuximab Tesirine Distribution and the Exploration of Patient Outcomes From the LOTIS-2 Clinical Trial in …
K Utsey, E Jordie, T Knab, K Wilkins, M Nickaeen, S Pantano, ...
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Articles 1–20