| Deubiquitinase inhibition by small-molecule WP1130 triggers aggresome formation and tumor cell apoptosis V Kapuria, LF Peterson, D Fang, WG Bornmann, M Talpaz, NJ Donato Cancer research 70 (22), 9265-9276, 2010 | 412 | 2010 |
| HCF-1 is cleaved in the active site of O-GlcNAc transferase MB Lazarus, J Jiang, V Kapuria, T Bhuiyan, J Janetzko, WF Zandberg, ... Science 342 (6163), 1235-1239, 2013 | 206 | 2013 |
| Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis H Sun, V Kapuria, LF Peterson, D Fang, WG Bornmann, G Bartholomeusz, ... Blood, The Journal of the American Society of Hematology 117 (11), 3151-3162, 2011 | 149 | 2011 |
| Activation of a novel Bcr/Abl destruction pathway by WP1130 induces apoptosis of chronic myelogenous leukemia cells GA Bartholomeusz, M Talpaz, V Kapuria, LY Kong, S Wang, Z Estrov, ... Blood 109 (8), 3470-3478, 2007 | 113 | 2007 |
| Recognition of a glycosylation substrate by the O-GlcNAc transferase TPR repeats K Rafie, O Raimi, AT Ferenbach, VS Borodkin, V Kapuria, DMF van Aalten Open biology 7 (6), 170078, 2017 | 58 | 2017 |
| A novel small molecule deubiquitinase inhibitor blocks Jak2 signaling through Jak2 ubiquitination V Kapuria, A Levitzki, WG Bornmann, D Maxwell, W Priebe, RJ Sorenson, ... Cellular signalling 23 (12), 2076-2085, 2011 | 47 | 2011 |
| Protein cross-linking as a novel mechanism of action of a ubiquitin-activating enzyme inhibitor with anti-tumor activity V Kapuria, LF Peterson, HDH Showalter, PD Kirchhoff, M Talpaz, ... Biochemical pharmacology 82 (4), 341-349, 2011 | 46 | 2011 |
| Association of-308 TNF-alpha promoter polymorphism with type 1 diabetes in North Indians SN Das, V Baniasadi, V Kapuria Int J Immunogenet 33 (6), 411-416, 2006 | 35 | 2006 |
| Proteolysis of HCF-1 by Ser/Thr glycosylation-incompetent O-GlcNAc transferase: UDP-GlcNAc complexes V Kapuria, UF Röhrig, T Bhuiyan, VS Borodkin, DMF van Aalten, V Zoete, ... Genes & development 30 (8), 960-972, 2016 | 27 | 2016 |
| Distinct OGT-binding sites promote HCF-1 cleavage T Bhuiyan, P Waridel, V Kapuria, V Zoete, W Herr PLoS One 10 (8), e0136636, 2015 | 19 | 2015 |
| Single nucleotide polymorphisms in TNF-α, TNFR2 gene and TNF-α production in Asian Indians R Gupta, V Kapuria, SN Das Immunological investigations 38 (3-4), 240-254, 2009 | 19 | 2009 |
| A small molecule deubiquitinase inhibitor increases localization of inducible nitric oxide synthase to the macrophage phagosome and enhances bacterial killing KM Burkholder, JW Perry, CE Wobus, NJ Donato, HD Showalter, ... Infection and immunity 79 (12), 4850-4857, 2011 | 18 | 2011 |
| Degrasyn-like symmetrical compounds: possible therapeutic agents for multiple myeloma (MM-I) Z Peng, DS Maxwell, D Sun, BAB Prasad, PT Schuber Jr, A Pal, Y Ying, ... Bioorganic & medicinal chemistry 22 (4), 1450-1458, 2014 | 16 | 2014 |
| The conserved threonine-rich region of the HCF-1PRO repeat activates promiscuous OGT: UDP-GlcNAc glycosylation and proteolysis activities V Kapuria, UF Röhrig, P Waridel, F Lammers, VS Borodkin, ... Journal of Biological Chemistry 293 (46), 17754-17768, 2018 | 7 | 2018 |
| Antitumor Activity and Mechanism of Action of a Novel Stat3 Inhibitor, WP1066, Against Human B-Cell Non-Hodgkin’s Lymphoma and Multiple Myeloma. LY Kong, V Kapuria, G Bartholomeusz, M Talpaz, W Priebe, NJ Donato Blood, The Journal of the American Society of Hematology 106 (11), 1489-1489, 2005 | 7 | 2005 |
| Inhibition of Usp9x deubiquitinase activity by WP1130 reduces Mcl-1 levels and induces apoptosis in cells from patients with plasma cell dyscrasia and drug-refractory multiple … H Sun, V Kapuria, LF Peterson, D Giannola, K Malathi, M Talpaz, ... Blood 116 (21), 3005, 2010 | 5 | 2010 |
| Tryphostin-analogs for the treatment of cell proliferative diseases NJ Donato, D Maxwell, M Talpaz, W Bornmann, Z Peng, A Pal, D Han, ... US Patent App. 12/307,088, 2010 | 4 | 2010 |
| A Novel Small-Molecule Approach To Inhibit Jak2 Tyrosine Kinase Signaling. V Kapuria, G Bartholomeusz, LY Kong, W Bornmann, Z Peng, A Pal, ... Blood, The Journal of the American Society of Hematology 110 (11), 1556-1556, 2007 | 2 | 2007 |
| Deubiquitinase Usp9X regulates cell survival and metabolic signal transduction in multiple myeloma cells LF Peterson, H Sun, V Kapuria, M Kandarpa, M Talpaz, AJ Jakubowiak, ... Blood 118 (21), 1835, 2011 | 1 | 2011 |
| WP1130 Inhibits Signaling through BCR-ABL Ubiquitination and Cytoplasmic to Aggresome Trafficking to Induce Apoptosis of CML Cells. NJ Donato, H Sun, V Kapuria, LF Peterson, G Bartholomeusz, ... Blood, The Journal of the American Society of Hematology 114 (22), 3303-3303, 2009 | 1 | 2009 |
Winship HerrUniversity of LausanneVerified email at unil.ch
