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Holger Heyn
Holger Heyn
CNAG-CRG
Verified email at cnag.crg.eu - Homepage
Title
Cited by
Cited by
Year
Global epigenomic reconfiguration during mammalian brain development
R Lister, EA Mukamel, JR Nery, M Urich, CA Puddifoot, ND Johnson, ...
Science 341 (6146), 1237905, 2013
18992013
A landscape of pharmacogenomic interactions in cancer
F Iorio, TA Knijnenburg, DJ Vis, GR Bignell, MP Menden, M Schubert, ...
Cell 166 (3), 740-754, 2016
16792016
Machine learning identifies stemness features associated with oncogenic dedifferentiation
TM Malta, A Sokolov, AJ Gentles, T Burzykowski, L Poisson, JN Weinstein, ...
Cell 173 (2), 338-354. e15, 2018
15272018
Comparative analysis of single-cell RNA sequencing methods
C Ziegenhain, B Vieth, S Parekh, B Reinius, A Guillaumet-Adkins, ...
Molecular cell 65 (4), 631-643. e4, 2017
13772017
Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome
J Sandoval, H Heyn, S Moran, J Serra-Musach, MA Pujana, M Bibikova, ...
Epigenetics 6 (6), 692-702, 2011
11632011
Distinct DNA methylomes of newborns and centenarians
H Heyn, N Li, HJ Ferreira, S Moran, DG Pisano, A Gomez, J Diez, ...
Proceedings of the National Academy of Sciences 109 (26), 10522-10527, 2012
8752012
DNA methylation profiling in the clinic: applications and challenges
H Heyn, M Esteller
Nature Reviews Genetics 13 (10), 679-692, 2012
8582012
Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis
S Moran, A Martínez-Cardús, S Sayols, E Musulén, C Balañá, ...
The Lancet Oncology 17 (10), 1386-1395, 2016
4312016
DNA methylation contributes to natural human variation
H Heyn, S Moran, I Hernando-Herraez, S Sayols, A Gomez, J Sandoval, ...
Genome research 23 (9), 1363-1372, 2013
4292013
SPOTlight: seeded NMF regression to deconvolute spatial transcriptomics spots with single-cell transcriptomes
M Elosua-Bayes, P Nieto, E Mereu, I Gut, H Heyn
Nucleic acids research 49 (9), e50-e50, 2021
3352021
Benchmarking single-cell RNA-sequencing protocols for cell atlas projects
E Mereu, A Lafzi, C Moutinho, C Ziegenhain, DJ McCarthy, ...
Nature biotechnology 38 (6), 747-755, 2020
3332020
A prognostic DNA methylation signature for stage I non-small-cell lung cancer
J Sandoval, J Méndez González, E Nadal, G Chen, FJ Carmona, S Sayols, ...
Journal of clinical oncology 31, 4140-4147, 2013
3092013
DNA methylation map of human atherosclerosis
S Zaina, H Heyn, FJ Carmona, N Varol, S Sayols, E Condom, ...
Circulation: Cardiovascular Genetics 7 (5), 692-700, 2014
2542014
Mutations in neutrophil elastase causing congenital neutropenia lead to cytoplasmic protein accumulation and induction of the unfolded protein response
I Köllner, B Sodeik, S Schreek, H Heyn, N von Neuhoff, ...
Blood 108 (2), 493-500, 2006
2212006
Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data
CH Holland, J Tanevski, J Perales-Patón, J Gleixner, MP Kumar, E Mereu, ...
Genome biology 21, 1-19, 2020
2202020
Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer
H Heyn, E Vidal, HJ Ferreira, M Vizoso, S Sayols, A Gomez, S Moran, ...
Genome biology 17, 1-16, 2016
2092016
DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker
H Heyn, FJ Carmona, A Gomez, HJ Ferreira, JT Bell, S Sayols, K Ward, ...
Carcinogenesis 34 (1), 102-108, 2013
1922013
Identity noise and adipogenic traits characterize dermal fibroblast aging
MC Salzer, A Lafzi, A Berenguer-Llergo, C Youssif, A Castellanos, ...
Cell 175 (6), 1575-1590. e22, 2018
1872018
Tutorial: guidelines for the experimental design of single-cell RNA sequencing studies
A Lafzi, C Moutinho, S Picelli, H Heyn
Nature protocols 13 (12), 2742-2757, 2018
1832018
Mex3a marks a slowly dividing subpopulation of Lgr5+ intestinal stem cells
FM Barriga, E Montagni, M Mana, M Mendez-Lago, ...
Cell stem cell 20 (6), 801-816. e7, 2017
1792017
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